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Santa Monica, CA, United States

Radiabeam Technologies, LLC | Date: 2011-03-08

A method for testing the sensitivity of electronic components and circuits against particle and photon beams using plasma acceleration, in which the flexibility of the multifaceted interaction can produce several types of radiation such as electron, proton, ion, neutron and photon radiation, and combinations of these types of radiation, in a wide range of parameters that are relevant to the use of electronic components in space, such as satellites, at high altitudes or in facilities that work with radioactive substances such as nuclear power plants. Relevant radiation parameter ranges are accessible by this method, which are hardly accessible with conventional accelerator technology. Because of the compactness of the procedure and its versatility, radiation testing can be performed in smaller laboratories at relatively low cost.

Agency: Department of Health and Human Services | Branch: National Institutes of Health | Program: SBIR | Phase: Phase I | Award Amount: 264.74K | Year: 2015

DESCRIPTION provided by applicant Robotic radiotherapy using extensively non coplanar beams has been shown effective to significantly improve radiation therapy dosimetry that leads to improved treatment outcome However current implementation of this technique by CyberKnife is inefficient and not optimal dosimetrically This has severely limited both the number of patients eligible for robotic radiotherapy and the achievable clinical outcome for those who have been treated In order to overcome these limitations we propose to develop a novel robotic radiotherapy system that can efficiently utilize the full potential of the non coplanar delivery space to treat the majority of radiotherapy patients Innovation The proposed system is highly innovative in the following aspect Integrated beam orientation and fluence optimization Significantly more compact linac to allow posterior beams Flexible field sizes and MLC resolution to efficiently treat most target sizes Integrated volumetric imaging system This project is proposed to design a hardware platform materializing such robotic radiotherapy system In order to reduce the gantry size both the linac length and the distance between the source and the MLC need to be significantly reduced We propose to design a new MV source to reduce linac length and provide the required dose rate for treatment The physical MLC leaf thickness cannot be substantially thinner than mm To achieve a high MLC resolution at the treatment distance a spacer is used in CyberKnife between the primary collimator and the MLC increasing the gantry dimension We propose to eliminate the spacer but vary the focus to tumor distances FTD to achieve desired field size and MLC resolution This requires optimization in an enormous solution space a capacity uniquely demonstrated by the p algorithm Volumetric imaging has been an indispensable component of modern radiotherapy but unfortunately missing from existing robotic systems The proposed new linac will be able to deliver kV imaging beams from the same MV linac which in combination with gantry or couch mounted imagers will allow volumetric imaging for more precise tumor targeting Aims Prototypical design of the accelerator to produce MV X rays Design incorporated imaging system Develop a conceptual design for the entire clinical system Impact Success of the Phase I project would lead to the design of the first MV linear accelerator capable of producing a competitively high dose rate of andgt cGy min at cm and kV imaging beams for image guided radiotherapy This paves the technical path to a new robotic radiotherapy system delivering radiation plans with dose conformality surpassing existing X ray platforms More importantly the significantly increased field size throughput and the volumetric imaging capacity would allow the new robotic system to compete for a much larger market including that for conventional linacs than the niche market CyberKnife currently commands PUBLIC HEALTH RELEVANCE Success of the proposed project would lead to the development of a novel radiation therapy device capable of significantly reducing the radiation dose deposited to healthy tissue during cancer treatment The final clinical system to be developed in Phase II would revolutionize the field of radiation therapy by allowing this precise tumor targeting to be achieved with a quick flexible robotic system enabling high patient throughput This system is expected to manage a wide range of diseases and treatment fractions thus having a broad clinical and commercial impact

Agency: Department of Defense | Branch: Missile Defense Agency | Program: SBIR | Phase: Phase I | Award Amount: 99.89K | Year: 2015

RadiaBeam Technologies, LLC (RBT) propose to develop a kilowatt (kW) range Ka band Solid State electronic amplifier klystron replacement. The system is based on highly innovative hybrid architecture with sequentially distributed dividing-combining. The architecture allows more than an order-of-magnitude higher power multiplication factor at enhanced efficiency and eased access for cooling and maintenance of amplifying modules. The proposed design enables elimination of warm-up delays and quiescent power consumption at high reliability and robustness enhanced by graceful degradation factor. (Approved for Public Release 15-MDA-8482 (17 November 15))

Agency: Department of Energy | Branch: | Program: SBIR | Phase: Phase I | Award Amount: 149.82K | Year: 2015

RF Breakdown RFBD) is a serious limitation in the performance of high gradient >200 MV/m) accelerators operating in W-band frequency range ~100 GHz). In order to study this phenomena at such high frequency, a special detector is required. Conventional detection instruments and methods, such as Faraday Cups, that are used to detect RFBD at lower frequencies are not capable of distinguishing the RFBD from the current jitter in the 100 GHz frequency range. In response to this problem, it is proposed to design and build a single-shot narrow-band terahertz spectrometer that will be able to detect the radiation spectrum widening due the RF pulse shortening cause by an RFBD. In Phase I, we will design, build and test at SLAC the 8- channel prototype of such spectrometer to prove the principle of concept, and to prepare for a commercial 32-channel design a prototype fabrication in Phase II. The goal of Phase I is to build an instrument that will be immediately used by SLAC National Accelerator Laboratory in their work on improving the performance of high-gradient 100 GHz accelerating structure for CLIC. The strategic goal of the Phase I and II of this project is to build a commercial prototype of the spectrometer that can become a useful and important instrument for a wide spectrum of applications, which include testing the THz sources and amplifiers, light source beamline diagnostics, general THz instrumentation and accelerator diagnostics.

Agency: Department of Homeland Security | Branch: | Program: SBIR | Phase: Phase II | Award Amount: 749.80K | Year: 2015

Mobile Non-Intrustive Inspection (NII) systems are advantageous as they can be deployed to where the greatest need exists, and they generally have small footprints, which is necessary in many locations. However, the currently deployed mobile NII systems do not offer effective material discrimination and sufficient penetration, which are critical for shielded radiological/nuclear threat identification. This is because the current generation of high-energy interlaced 6/9 MeV X-ray sources needed for good material discrimination are too large and heavy to fit into a compact mobile system. In this project, RadiaBeam will develop an X-Ray source that meets the small size and weight required for a mobile scanner yet can provide the imaging performance required to detect shielded threats. We will build a dual-energy, 6/9 MeV linac that, combined with all support infrastructure (electronics, cooling, shielding), will be half the weight and volume of the dual energy lilacs on the market today. The X-ray source will find immediate application.

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