Devmurari V.P.,Smtrb Patel Mahila Pharmacy College |
Shivanand P.,Smtrb Patel Mahila Pharmacy College |
Goyani M.B.,Smtrb Patel Mahila Pharmacy College |
Jivani N.P.,Smtrb Patel Mahila Pharmacy College
International Journal of Applied Chemistry | Year: 2010
A series of methyl 2-substituted benzimidazole-1-carbodithioates were successfully synthesized. Benzimidazoles was prepare by condensation of o-phenylenediamine with substituted Carboxylic acid and by condensation of substituted benzaldehyde, Sodium metabisulphate and o-phenylenediamine. Methyl Carbodithioate derivative of the benzimidazole were prepared by reaction with carbon disulfide. In vitro antibacterial activity of the synthesized compounds was analyzed against three grampositive bacterial species and gram negative microorganism by agar well-diffusion Method (Cup plate method). © Research India Publications.