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Montevideo, Uruguay

Penanda S.,Quimica Farmaceutica | Scarone L.,Quimica Farmaceutica | Manta E.,Quimica Farmaceutica | Serra G.,Quimica Farmaceutica
Khimiya Geterotsiklicheskikh Soedinenii | Year: 2011

A rapid and efficient methodology to prepare 2,4'-bi-1,3-azoles as scaffolds for biologically active marine natural products is described. Hantzsch reaction and oxidative cyclodehydration of ß-hydroxyamides or thioamides were used to construct the azole rings. The obtained biheterocycles displayed no citotoxicity on HCT-15 cell line. Source

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