ZNA Queen Paola Childrens Hospital

Antwerpen, Belgium

ZNA Queen Paola Childrens Hospital

Antwerpen, Belgium
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Van Den Akker M.,Zna Queen Paola Childrens Hospital | Vervloessem D.,Zna Queen Paola Childrens Hospital | Huybrechs A.,Heilig Hart Hospital | Declercq S.,ZNA Middelheim Hospital | Van der Werff Ten Bosch J.,UZ Brussel
Journal of Medical Case Reports | Year: 2017

Background: Pediatric germ cell tumors account for approximately 3.5 % of all childhood cancers for children under the age of 15 years. Up to one-third are extragonadal neoplasms. Germ cell tumors are a heterogeneous group of malignant tumors with a wide variety of histopathological features. Yolk sac tumor is the predominant variant in newborns and younger children. We report for the first time, the presentation of a primary yolk sac tumor in the abdominal wall of a small child. Case presentation: An 18-month-old white girl underwent resection of a small, round subcutaneous lump (1.5×1.3×0.8 cm) of the abdominal wall in her right hypochondriac region. The histopathology was compatible with yolk sac tumor. Her alpha-fetoprotein was initially elevated but normalized after the resection. Magnetic resonance imaging of her abdomen was normal. The surgeon decided to observe and follow her alpha-fetoprotein level closely. One year after resection a local recurrence appeared and her alpha-fetoprotein rose to 58 ng/mL. The surgeon performed a wide resection of the lesion with normalization of her alpha-fetoprotein. Follow-up consisted of measuring alpha-fetoprotein, clinical evaluation, and abdominal ultrasound. Conclusions: Clinicians should be aware that a yolk sac tumor can present in an unusual extragonadal place, for example in this case it was subcutaneous. In some cases, conservative treatment can be carried out with careful monitoring of the patient and their alpha-fetoprotein. © 2017 The Author(s).


Driesen Y.,University of Antwerp | Driesen Y.,Universitair Ziekenhuis Antwerpen | Verweij M.,University of Antwerp | De Maeseneer M.,Erasmus University Rotterdam | And 4 more authors.
Pediatric Infectious Disease Journal | Year: 2015

Stroke and deep venous thrombosis are rare complications of varicella zoster infection. We report 3 cases of children with a stroke and 1 case of a boy with a deep venous thrombosis after recent chicken pox. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.


PubMed | Sint Augustinus Hospital and ZNA Queen Paola Childrens Hospital
Type: Journal Article | Journal: European journal of pediatric surgery reports | Year: 2016

Intestinal malrotation complicated by the development of midgut volvulus presents a difficult management dilemma because of the risk of short bowel syndrome. Here, we present our experience with a case of severe intestinal ischemia after derotation in a newborn successfully managed using systemic tissue plasminogen activator. The present report supports the usefulness of thrombolysis as a therapeutic option for reperfusion of ischemic small bowel due to midgut volvulus in neonates.

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