Mile End Road, United Kingdom
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Oikarinen S.,University of Tampere | Tauriainen S.,University of Tampere | Tauriainen S.,University of Turku | Hober D.,Lille 2 University of Health and Law | And 21 more authors.
Diabetes | Year: 2014

Enteroviruses (EVs) have been connected to type 1 diabetes in various studies. The current study evaluates the association between specific EV subtypes and type 1 diabetes by measuring typespecific antibodies against the group B coxsackieviruses (CVBs), which have been linked to diabetes in previous surveys. Altogether, 249 children with newly diagnosed type 1 diabetes and 249 control children matched according to sampling time, sex, age, and country were recruited in Finland, Sweden, England, France, and Greece between 2001 and 2005 (mean age 9 years; 55% male). Antibodies against CVB1 were more frequent among diabetic children than among control children (odds ratio 1.7 [95% CI 1.0-2.9]), whereas other CVB types did not differ between the groups. CVB1-associated risk was not related to HLA genotype, age, or sex. Finnish children had a lower frequency of CVB antibodies than children in other countries. The results support previous studies that suggested an association between CVBs and type 1 diabetes, highlighting the possible role of CVB1 as a diabetogenic virus type. © 2014 by the American Diabetes Association.


Zhou L.N.,Wuhan University | Cheng Y.J.,Wuhan University | Xu E.M.,Huazhong University of Science and Technology | Sterr U.O.,Queen Mary and Westfield College | And 2 more authors.
Electronics Letters | Year: 2011

A new high-Q infinite impulse response (IIR) microwave photonic filter is demonstrated, in which two active recirculating delay line loops based on a semiconductor optical amplifier (SOA) are cascaded. Due to cross-gain modulation in the SOA, interferences between light beams travelling along different paths are removed, ensuring stable operation and linearity of the electrical transfer function. The whole transfer function comprises a term representing a cascade response of two IIR filters, which significantly increases the free spectral range and the Q factor. The filter exhibits a Q factor of 1870 with a rejection ratio of 25dB. © 2011 The Institution of Engineering and Technology.


News Article | February 27, 2017
Site: www.prweb.com

Thomas Slover has joined Hiersche, Hayward, Drakeley & Urbach, P.C. as a shareholder, where his experience representing buyers, sellers, management companies, developers and financial institutions will strengthen the firm’s commitment to the city’s growing commercial real estate industry. “We are thrilled to welcome Tom to the firm,” said Bill Hayward, President. “He has an excellent and established reputation in commercial real estate law. I truly believe that Tom not only provides the kind of service and counsel that our clients are accustomed to, but that he also has the ability and relationships to grow our firm’s real estate practice.” Mr. Slover practices in the areas of commercial real estate, leasing, banking, corporate and partnership law. At Hiersche, Hayward, Drakeley & Urbach, P.C., he will provide legal guidance in a variety of real estate matters, including acquisitions, dispositions, development and finance, leasing, foreclosures, property management, and service contracts. Among his clients, Mr. Slover serves as counsel to a number of healthcare real estate developers in connection with projects throughout several states. Mr. Slover earned a Bachelor of Arts degree in Economics from Vanderbilt University (1989) and his Juris Doctor degree from Southern Methodist University Dedman School of Law (1994). He also holds an LLM (with merit) in Finance and Banking Law from the University of London, Queen Mary and Westfield College (1998). Hiersche, Hayward, Drakeley & Urbach, P.C. is a full-service commercial law firm located in Addison, Texas. Their attorneys provide legal representation in a broad range of practice areas, including complex commercial litigation, business, real estate, mergers and acquisitions, executive employment representation, insurance defense, intellectual property, bankruptcy, creditor’s rights, taxation, and estate planning. For more information, visit the firm’s website at http://www.hhdulaw.com


Parsons S.,Imperial College London | Parsons S.,Queen Mary and Westfield College | Saffiotti A.,Roosevelt University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2014

We introduce a new application of qualitative models of uncertainty. The qualitative analysis of a numerical model of uncertainty reveals the qualitative behaviour of that model when new evidence is obtained. This behaviour canbe compared with an expert's specifications to identify those situations in which the model does not behave as expected. We report the result of experlments performed using a probability model, and a model based on the Dempster-Shafer theory of evidence.


Patent
University of Brescia and Queen Mary And Westfield College | Date: 2011-01-05

The present invention deals with a method to search one item or a group of similar items within a number of items stored in a database, where each item is assigned with a representative graphical information, such as an image, sound, or text which identifies and characterizes the item itself. The method includes the following steps:a) organizing the database as a relational structure where all the representative information are grouped in a number of subsets according to a predetermined criterion of similarity, so that the information contained in each subset show differences in the informative content below a predetermined threshold value;b) associating to at least one of the subsets a probability value which depends on the subset content and/or from the results of previous search procedures and/or from the status of the ongoing search;c) randomly selecting one among the subsets according to the probability value assigned at the previous step, and simultaneously reproducing at least one part of the information contained in the same subset;d) if the searched item is not within the reproduced ones, repeating at least the previous step, until the user is able to find some interesting information.


A sensor device 100, in particular being adapted for sensing of substances, which comprises a sensor filament 10, which has a first end providing an exposed sensing surface 11 and a second end 12 being connectable with a metering device 220, and a recessed sensor tip 20, which has an inner space 21 to which the sensing surface 11 is exposed, further including a first capillary 13 including the sensor filament 10 and having a first capillary end 14, where the sensing surface 11 is exposed to the inner space 21 of the recessed sensor tip 20, and a second capillary 22 being fixedly connected to the first capillary end 14 and providing the recessed sensor tip 20. Furthermore, a measuring apparatus 200 including the sensor device 100 and a method of manufacturing the sensor device 100 are described.


Patent
Queen Mary And Westfield College | Date: 2012-12-21

A composition for making a cement or an implant, the composition comprising a silicate glass and at least one compound selected from the group consisting of a calcium phosphate salt, a strontium phosphate salt and a phosphate glass.


Patent
Queen Mary And Westfield College | Date: 2010-04-28

The present invention provides isoquinoline, tetrahydroisoquinoline and tetrahydropyridopyrimidine compounds that induce cell death by apoptosis and uses of the compounds in medicine, especially their use for treating cancer and other diseases.


Patent
Queen Mary And Westfield College | Date: 2010-09-15

The use of monoclonal antibodies to the angiotensin-II type-I receptor is provided for the treatment of vascular smooth muscle cell proliferation. Specifically, a monoclonal antibody or a fragment thereof to a peptide comprising the N-terminal portion of the angiotensin-II type-I receptor defined by the sequence MILNSSTEDG IKRIQDDCPK AGRHNYIFVM IPTLYSIIFV VGIFG or a fragment thereof is provided for use in the treatment of vascular smooth muscle (VSM) cell proliferation.


Ishtiaq S.,Queen Mary and Westfield College | O'Hearn P.W.,Queen Mary and Westfield College
ACM SIGPLAN Notices | Year: 2011

Reynolds has developed a logic for reasoning about mutable data structures in which the pre- and postconditions are written in an intuitionistic logic enriched with a spatial form of conjunction. We investigate the approach from the point of view of the logic BI of bunched implications of O'Hearn and Pym. We begin by giving a model in which the law of the excluded middle holds, thus showing that the approach is compatible with classical logic. The relationship between the intuitionistic and classical versions of the system is established by a translation, analogous to a translation from intuitionistic logic into the modal logic S4. We also consider the nation completeness of the axioms. BI's spatial implication is used to express weakest preconditions for object-component assignments, and an axiom for allocating a cons cell is shown to be complete under an interpretation of triples that allows a command to be applied to states with dangling pointers. We make this latter a feature, by incorporating an operation, and axiom, lor disposing of memory. Finally, we describe a local character enjoyed by specifications in the logic, and show how this enables a class of frame axioms, which say what parte of the heap don't change, to be inferred automatically. © 2000 ACM.

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