Cai Y.M.,Quanzhou Medical College
Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery | Year: 2011
To study the expression of P57(kip2) and Maspin in the pathological scar and their possible role in the pathogenesis of abnormal scars. Immunohistochemistry integrated image analysis and reverse transcription polymerase chain reaction (RT-RCR) were performed to detect the expression of P57(kip2) and Maspin in hypertrophic scar, keloid, mature scar and normal skin. Statistics was used to analyze the datas. The expression of P57(kip2) protein was fixed to fibroblast intranuclear in abnormal scar, and the expression of P57(kip2) protein and P57(kip2) mRNA decreased (P < 0.05). The expression of Maspin protein was fixed to fibroblast cytoplasm and intranuclear in abnormal scar, and the expression of Maspin protein and Maspin mRNA decrease, compared with that in normal group (P < 0.05). There was positive correlation between P57(kip2) protein and Maspin protein expression (P < 0.01). The decreased expression of P57(kip2) and Maspin in abnormal scar shows that they are cicatrix-related genes. There is a positive relationship between the two genes. It may be one of the mechanisms of pathogenesis of abnormal scar. It makes effect through fibroblasts.
Yulan Z.,Quanzhou Medical College |
Xin H.,Huaqiao University
RISTI - Revista Iberica de Sistemas e Tecnologias de Informacao | Year: 2016
with the wide application of biometric identification technology, the security defects are gradually exposed. The encryption technology which was combined with Biometric cryptography and biometric identification technology is to compensate for lack of biometrics in terms of security caused. Based on the existing research of face biometrics technology, the face biometric encryption algorithm with security and fault tolerance was proposed: fuzzy random cyclic mapping. In each cycle, the use of encryption model is the key of the previous cycle as a random seed to generate a mapping matrix. The facial features of the user was mapped to formate a cyclic random mapping process. In the process of encryption, fault tolerant technology was used to reduce the effect of random noise and the characteristics of the legitimate users face image for recognition rate. The experiment showed that the biological characteristics of face encryption algorithm was in high security based on fuzzy random cyclic mapping.
Chen Y.-F.,Quanzhou Medical College |
Wang Z.-H.,Fujian Medical University |
Wang Z.-H.,Friedrich - Schiller University of Jena |
Chen Z.-K.,Fujian Medical University |
And 2 more authors.
Pediatric Research | Year: 2013
Background:Maternal hypoxia induces sustained fetal adaptations associated with changes in gene expression. We hypothesized that intermittent maternal hypoxia has an influence on regional expression of endothelial nitric oxide synthase (eNOS) in fetal arteries of New Zealand White rabbits.Methods:Timed- pregnant New Zealand White rabbits (term = 30 ± 1 d) were randomly assigned to a normoxic control group (n = 5) or a hypoxia group (12% O 2, n = 5) during days 10-29 of pregnancy. At the end of pregnancy (29 d gestation), blood samples were collected from mothers and fetuses. Carotid and femoral arteries of fetuses were extracted for eNOS mRNA and protein concentration and analysis of total NOS activities.Results:Our data demonstrate that chronic intermittent maternal hypoxia significantly increased eNOS mRNA and protein concentrations and total NOS activities in carotid artery segments but decreased eNOS mRNA and protein concentrations and total NOS activities in femoral artery segments in the same fetuses. Vascular endothelial cells, but not smooth muscle cells, of fetal rabbits exhibited positive immunostaining for the eNOS protein.Conclusion:These observations suggest that chronic hypoxia can regulate regional expression of eNOS as an adaptive response to hypoxic stress in fetal arteries. Copyright © 2013 International Pediatric Research Foundation, Inc.
Fang C.,Key Laboratory of Biopesticide and Chemical Biology |
Fang C.,Fujian Agriculture and forestry University |
Zhuang Y.,Quanzhou Medical College |
Xu T.,Key Laboratory of Biopesticide and Chemical Biology |
And 5 more authors.
Journal of Chemical Ecology | Year: 2013
Gene expression of phenylalanine ammonia-lyase (PAL) in allelopathic rice PI312777 was inhibited by RNA interference (RNAi). Transgenic rice showed lower levels of PAL gene expression and PAL activity than wild type rice (WT). The concentrations of phenolic compounds were lower in the root tissues and root exudates of transgenic rice than in those of wild type plants. When barndyardgrass (BYG) was used as the receiver plant, the allelopathic potential of transgenic rice was reduced. The sizes of the bacterial and fungal populations in rice rhizospheric soil at the 3-, 5-, and 7-leaf stages were estimated by using quantitative PCR (qPCR), which showed a decrease in both populations at all stages of leaf development analyzed. However, PI312777 had a larger microbial population than transgenic rice. In addition, in T-RFLP studies, 14 different groups of bacteria were detected in WT and only 6 were detected in transgenic rice. This indicates that there was less rhizospheric bacterial diversity associated with transgenic rice than with WT. These findings collectively suggest that PAL functions as a positive regulator of rice allelopathic potential. © 2013 Springer Science+Business Media New York.
You J.-H.,Fujian Medical University |
Lv G.-R.,Fujian Medical University |
Lv G.-R.,Quanzhou Medical College |
Liu X.-L.,Fujian Medical University |
He S.-Z.,Fujian Medical University
Prenatal Diagnosis | Year: 2014
Aim: The aims of this article are to establish three-dimensional ultrasonographic nomograms of normal fetal spleen size and to evaluate the clinical application value. Methods: An observational, cross-sectional study was performed on 455 women with a normal singleton pregnancy between 18 and 38weeks' gestational age (GA). Fetal spleen volume was measured using three-dimensional ultrasound equipped with virtual organ computer-aided analysis, and biometric parameters were assessed in multiplanar mode to create reference ranges to GA. Thirty cases were randomly selected to conduct reliability analyses via intraobserver and interobserver ultrasonographic measurement. Moreover, 50 cases of suspected splenic malformations were evaluated by the newly established nomograms and followed up subsequently. Results: Using regression formulas, we found that fetal spleen size increased with GA. We observed strong reliability in intraobserver and interobserver volume measurements with intraclass correlation coefficients of 0.994 and 0.962. Bland-Altman analyses showed narrow limits of agreement [intraobserver: (-3.2 to 3.5)%; interobserver: (-3.2 to 4.3)%]. Of the 50 cases with suspected splenic malformations, six cases of splenomegaly and one case of splenic cyst were diagnosed. Conclusion: Three-dimensional ultrasound nomograms of normal fetal spleen size across a range of GA have a strong diagnostic value. Volume measurements with good reliability were optimal in clinical practice. © 2014 John Wiley & Sons, Ltd.