Punjab Medical College Faisalabad
Punjab Medical College Faisalabad
Azam Z.,Dow University of Health Sciences |
Shoaib M.,Memom Medical Institute Hospital |
Javed M.,Punjab Medical College Faisalabad |
Sarwarm M.A.,DHQ Hospital Faisalabad |
And 2 more authors.
Pakistan Journal of Medical Sciences | Year: 2017
Objective: The uridine nucleotide analogue sofosbuvir is a selective inhibitor of hepatitis C virus (HCV) NS5B polymerase approved for the treatment of chronic HCV infection with genotypes 1 4. The objective of the study was to evaluate the interim results of efficacy and safety of regimens containing Sofosbuvir (Zoval) among Pakistani population with the rapid virologic response (RVR2/4 weeks) with HCV infections. Methods: This is a multicenter open label prospective observational study. Patients suffering from chronic Hepatitis C infection received Sofosbuvir (Zoval) 400 mg plus ribavirin (with or without peg interferon) for 12/24 weeks. The interim results of this study were rapid virological response on week 4. Data was analyzed using SPSS version 21 for descriptive statistics. Results: A total of 573 patients with HCV infection were included in the study. The mean age of patients was 46.07 ± 11.41 years. Out of 573 patients 535 (93.3%) were treatment naive, 26 (4.5%) were relapser, 7 (1.2%) were non-responders and 5 (1.0%) were partial responders. A rapid virologic response was reported in 563(98.2%) of patients with HCV infection after four weeks of treatment. The treatment was generally well tolerated. Conclusion: Sofosbuvir (Zoval) is effective and well tolerated in combination with ribavirin in HCV infected patients. © 2017 Professional Medical Publications. All rights reserved.
Rathore A.H.,Foundation Hospital Rajana |
Hussain R.,Punjab Medical College Faisalabad |
Rathore F.,Foundation Hospital Rajana
Pakistan Journal of Medical Sciences | Year: 2010
Pyloric duplication cyst is one of the rarest congenital anomalies. We present such a case in a boy of 6-1/2 years old who was treated by us successfully. The theories of its embryogenesis, mode of presentations, diagnosis and treatment are discussed.
Tarique N.,Punjab Medical College Faisalabad |
Alam M.A.,Institute of Public Health Lahore |
Tahir S.,Fatima Memorial Medical and Dental College |
Shahid U.,Sharif Medical and Dental College
Pakistan Journal of Medical and Health Sciences | Year: 2012
Objective: To assess oral hygiene in children in sports and to determine various factors affecting oral health. Subjects and methods: This descriptive cross-sectional study was carried out in 150 children in one month. The study was conducted at Green Cricket Academy Summer Camp Model Town Lahore. The children aged between 10-14 years attending cricket summer camp were included. The children above 14 years of age, craniofacial disorders and history of any systemic disease were excluded from the study. For data collection procedure, formal permission was taken from the concerned stake holder of the cricket ground to collect relevant data regarding the oral dental knowledge and practice. Results: Regarding respondent's oral health status, poor 23, average 66 and 61 were represented as good in their oral health status. The respondent's visits to the dentists with oral dental health, 4 poor, 8 average and 1 good were visiting the dentist regularly and 19 poor, 57 average and 61 good were visiting the dentist occasionally. The regularity of the brushing with oral dental health status, 21 poor, 55 average and 59 good were brushing regularly and 2 poor, 9 average and 3 good were brushing occasionally. The respondents to the habit of taking diet included fruit, meat and vegetables with oral dental health status, 4 poor, 27 average and 35 good were taking fruit, meats and vegetables in their diets while 19 poor, 38 average and 27 good were not taking fruit, meats and vegetables in their diets. The habit of taking sweets with oral dental health status of respondents, 22 poor, 46 average and 40 good were in a habit of taking sweets while 1 poor, 19 average and 22 good were not taking sweets. Conclusion: Education about dental health in playgrounds can lead to improve dental hygiene practice, health and better outcomes.