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Philadelphia, PA, United States

Agency: National Aeronautics and Space Administration | Branch: | Program: SBIR | Phase: Phase II | Award Amount: 749.75K | Year: 2015

This project will achieve a wrist-worn actigraphy device called STARwatch, designed specifically for space exploration environments. It will provide a minimally obtrusive, objective measure that evaluates astronaut sleep-wake activity and light exposure. This project will leverage our second-generation actigraphy device that has already been validated in controlled laboratory experiments against gold-standard polysomnography. The compact wrist-worn device includes sensors to collect sleep metrics and will also serve as a wireless hub to collect real-time physiological data from other body-worn sensors (e.g., heart rate, EEG). It will use standardized wireless communication protocols (e.g., Bluetooth) to automatically uplink data to the ISS network (no astronaut time required). Data will automatically be integrated into medical operations support systems adhering to NASA data requirements (e.g., HL7), providing immediate feedback to astronauts and flight surgeons to aid in decision-making relative to astronaut medical, behavioral health and performance issues. During Phase II, we will conduct user testing and validation in a space flight analog environment, complete product refinements, and certify STARwatch for spaceflight. (Phase II TRL of 7-8).

Pulsar Informatics, Inc. | Date: 2013-08-27

Methods are provided for calibrating stimulus-response test systems which include a stimulus output device for delivering a stimulus to a subject, and a response input device for receiving a response from the subject, said response input device comprising a response actuator that is capable of responding in human-like fashion to the stimulus-response test using variable motion control signals comprising one or more time offsets and one or more activation values, said activation values comprising variable speeds and forces for the response motion.

Systems and methods for inter-population assessment of neurobehavioral status employ neurobehavioral profiles to accommodate differing external conditions. Population profiles and external condition data are provided to a neurobehavioral performance model to determine neurobehavioral status under external conditions. Alternatively, neurobehavioral performance values may be retrieved from the profile when such values are stored in conjunction with external condition data. Comparisons of the resulting neurobehavioral status(es) are then determined, and may comprise without limitation one or more of: performance deltas, statistical parameter differences, rankings, above/below performance threshold determinations, pass/fail indicators, and countermeasure recommendations. Populations may comprise pluralities, individuals and empty (null) sets. Comparisons may also pertain to one or more relevant times of interest and one or more sets of testing conditions. Fields of application include (without limitation) operational and military fatigue management, medical diagnosis and treatment, fatigue countermeasure training and individualization, sleep research, academic and scientific research, and/or the like.

Systems and methods for analyzing the results of a diagnostic-assessment test result of a subject with respect to those of a comparison population or subpopulation of interest are disclosed. A first set of testing conditions and/or demographic characteristics and their corresponding values are used optionally to identify a subpopulation of interest and select appropriate data from a general-population database. A second (and optionally a third) set of testing conditions and/or demographic characteristics (which may optionally be identical to the first) are then used to project either or both of the subjects test score or the test scores for the population or optional subpopulation of interest to a common basis of testing conditions and/or demographic characteristics using one or more projection functions specific to the testing condition and/or demographic characteristic, as applied to a particular test. A metric of comparison is then determined for the testing subject with this projected data.

Pulsar Informatics, Inc. | Date: 2012-07-12

Systems and methods for modulating a subjects neurobehavioral status by a task-dependent arousal index are provided. Neurobehavioral status may be measured or model-predicted, and the arousal index reflects the composite effect on the subjects neurobehavioral performance of behavioral, environmental, psychological, and physiological factors of the subjects performing an assigned task. Task arousal index may be selected from a database, provided by user input, or combined in real time from sensor data.

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