Pt Jnm Medical College Raipur

Lal Bahadur Nagar, India

Pt Jnm Medical College Raipur

Lal Bahadur Nagar, India
SEARCH FILTERS
Time filter
Source Type

Bit A.,National Institute of Technology Raipur | Bissoyi A.,National Institute of Technology Raipur | Sinha S.K.,National Institute of Technology Raipur | Patra P.K.,Pt Jnm Medical College Raipur | Saha S.,SUNY Downstate Medical Center
Proceedings - 32nd Southern Biomedical Engineering Conference, SBEC 2016 | Year: 2016

Colonization of bacteria such as Staphylococus or microbial growth forming layer of bio-film on the surface of implants inhibits osteo-integration on the surface of implants, and simultaneously resists the host defence mechanism on these bacteria. It leads to prognosis of surgical intervention. Titanium based implant (Ti6Al4V) provides the surface for enhanced osteo-integration, and it is biocompatible. But adhesion of bio-film on the surface of Ti-based implant never had been restricted. However, in case of low-cost metallic implant like SS 316, corrosion is another critical phenomenon. Graphene based composite multi-layer coating is therefore introduced on both Ti and SS 316 based implant using electrophoretic deposition process. Multi-layer thickness of graphene is ensured by Raman Spectroscopy. Coated implants made up of both types of metal are tested in simulated body fluid (SBF) for invitro study, and at invivo condition. Integration of graphene in micro-environment with enhancement of osteo-integration, and inhibition of bio-film adhesion and corrosion phenomena was characterised by Adhesion assay, Biofilm assay. Tests reveal enhanced osteogenic differentiation. Simultaneously, it shows restrict bio-film formation, corrosion activity, preventing bacterial adhesion and biofilm formation on both metallic implants. © 2016 IEEE.


Abha S.,Pt Jnm Medical College Raipur | Chandrashekhar S.,Pt Jnm Medical College Raipur | Sonal D.,Shri Ram Hospital
Journal of Obstetrics and Gynecology of India | Year: 2016

Background: MMR has always been recognized as an important indicator of quality of health services. The MMR in India has so far not reached up to the required MDG 2015. If we look into this matter with the eagle’s eye view, then there are certain gray areas which need attention. For this, it is not the maternal mortality but the maternal near miss which has to be focused. Objectives: To audit the maternal near miss in our institution and to review the pathways that lead to severe maternal morbidity and death. Methods: Prospective observational study from September 2013 to August 2015 in Dr. Bhim Rao Ambedkar Memorial Hospital, Raipur. Maternal near miss cases were identified based on WHO criteria 2009, recorded, and studied. Results: There were 13,895 live births, 211 maternal near miss, and 102 maternal deaths. Maternal near miss to mortality ratio was 2:1. Maternal near miss incidence ratio was 15.18/1000 live births. Mortality index was 32.58 %. Hemorrhage and hypertensive disorders of pregnancy toped the list of the leading causes of near miss morbidity. The near miss events were more common in the primipara (39 %), with age group 21–30 years and in the third trimester at the time of admission. Conclusion: Auditing maternal near miss can help in reducing their morbidity and mortality in our institution. Similar audit between other institute, state, and countries may help to hasten the slow progress of reducing maternal mortality. © 2016 Federation of Obstetric & Gynecological Societies of India


PubMed | Pt Jnm Medical College Raipur and Shri Ram Hospital
Type: Journal Article | Journal: Journal of obstetrics and gynaecology of India | Year: 2016

MMR has always been recognized as an important indicator of quality of health services. The MMR in India has so far not reached up to the required MDG 2015. If we look into this matter with the eagles eye view, then there are certain gray areas which need attention. For this, it is not the maternal mortality but the maternal near miss which has to be focused.To audit the maternal near miss in our institution and to review the pathways that lead to severe maternal morbidity and death.Prospective observational study from September 2013 to August 2015 in Dr. Bhim Rao Ambedkar Memorial Hospital, Raipur. Maternal near miss cases were identified based on WHO criteria 2009, recorded, and studied.There were 13,895 live births, 211 maternal near miss, and 102 maternal deaths. Maternal near miss to mortality ratio was 2:1. Maternal near miss incidence ratio was 15.18/1000 live births. Mortality index was 32.58%. Hemorrhage and hypertensive disorders of pregnancy toped the list of the leading causes of near miss morbidity. The near miss events were more common in the primipara (39%), with age group 21-30years and in the third trimester at the time of admission.Auditing maternal near miss can help in reducing their morbidity and mortality in our institution. Similar audit between other institute, state, and countries may help to hasten the slow progress of reducing maternal mortality.


PubMed | Pt Jnm Medical College Raipur and SRL Ltd
Type: Journal Article | Journal: Translational research : the journal of laboratory and clinical medicine | Year: 2015

India tops the list of countries with sickle cell disease (SCD) with an estimated 44,000 live births in 2010 and a prevalence of 10%-33%. In the present study, the first from India, we have investigated the effect of genetic variants in the BCL11A, the HMIP (HBS1L-MYB intergenic polymorphism) locus, in addition to the HBB locus, which are known to be associated with fetal hemoglobin (HbF) levels, a major modulator of the disease phenotype. The present study was conducted on 240 individuals with SCD and 60 with sickle cell trait. Genotyping was performed for the BCL11A rs11886868 and rs34211119; HMIP rs9399137, rs189600565, rs7776196, rs34778774, and rs53293029; HBG2 Xmn1 polymorphism rs7482144; and -68C>T HBD promoter polymorphism. All the 3 quantitative trait loci were associated with HbF levels in Indian patients with SCD. The highest difference was seen in the Xmn1 single-nucleotide polymorphism, which accounted for 11% of the trait variance, the BCL11A rs11886868 for 3.65%, whereas the HMIP rs9399137 for 3.8%. The present study indicates the BCL11A, HMIP, and -globin region to be associated with increased HbF levels in Indian patient. Further interrogation of these genotypes with respect to pain crisis is warranted in this population, which may help in prognostication, as also a genome-wide association study, which may help uncover new loci controlling HbF levels.

Loading Pt Jnm Medical College Raipur collaborators
Loading Pt Jnm Medical College Raipur collaborators