Pt. B. D. Sharma

Rohtak, India

Pt. B. D. Sharma

Rohtak, India

Time filter

Source Type

Arora M.K.,LHMC and Associated Hospitals | Seth S.,Pt. B.D. Sharma | Dayal S.,Venereology and Leprology | Trehan A.S.,Pt. B.D. Sharma | Seth M.,Pt. B D. Sharma
Clinical Laboratory | Year: 2014

Background: Acne vulgaris is one of the most common skin conditions affecting young adults. The relationship between lipid profile or lipid ratios and acne is not widely reported. Methods: A case control study was performed in 90 females with severe acne vulgaris. Lipid profiles were measured, lipid ratios were calculated, and results were compared with 90 age matched healthy controls. Results: Total cholesterol, LDL-C, HDL-C, Apo A1, though, were significantly higher in patients as compared to healthy controls but all the levels in patients were within normal range so we calculated lipid ratios for TC/HDL, LDL/HDL, TG/HDL, Apo B/Apo A1, Atherogenic index of plasma and found that all the ratios were significantly higher as compared to controls using a t-test. The area under receiver operating characteristic curve was > 0.7 for all the lipid ratios and sensitivity and specificity were calculated for all the ratios and it was highest for Apo A1/Apo B. Conclusions: We suggest using lipid ratios as a screening test in females with acne vulgaris to diagnose dyslipidemia at an early stage but further studies are required to see the effect of treating hyperlipidemia in females with severe acne vulgaris.


Chandi A.,Pt. B. D. Sharma | Jain S.,Pt. B. D. Sharma | Yadav S.,Pt. B. D. Sharma | Gurawalia J.,Pt. B. D. Sharma
Case Reports in Women's Health | Year: 2016

Introduction Gut prolapse through vagina is rare complication with only few cases reported in the literature. This article highlights untrained professionals induced obstetrical trauma as a cause of vaginal evisceration leading to serious but preventable complications. Presentation of Case Case 1: A 27 years old female, P2L0, had full term vaginal delivery of an IUD baby and presented 4 days later with small bowel evisceration through posterior vaginal wall. Case 2: A 24 years old female, P1A1 had underwent unsafe abortion and presented in shock, with small bowel evisceration through anterior uterine wall. Case 3: A 26 years female, P2A1, underwent evacuation for incomplete abortion and presented with omental prolapse through anterior uterine wall. Discussion Obstetrical trauma with associated evisceration of intraabdominal contents is a potentially serious complication that requires surgical intervention. General awareness may decrease these unsafe practices and thus would have impact in reducing maternal morbidity and mortality. © 2016 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license.


Singhal S.,Pt. B. D. Sharma | Bala M.,Pt. B. D. Sharma | Kaur K.,Pt. B. D. Sharma
Saudi Journal of Anaesthesia | Year: 2014

Background and Objective: There are various techniques to identify epidural space but superiority of one technique over other has not been adequately studied. We conducted a study to Compare and evaluate the three techniques for epidural space localization that is, loss of resistance (LOR) syringe technique, balloon technique and drip infusion technique. Materials and Methods: Seventy-five patients of either sex, belonging to American Society of Anesthesiologists physical status Class 1 or 2, between 20 and 50 years of age, scheduled to undergo lower abdominal and lower limb surgeries were randomly allocated to one of the three groups (n = 25 each) depending upon epidural space localization. In Group I, epidural space localization was done with LOR syringe technique. In Group II Balloon technique and in Group III drip infusion technique was used. Distance of the epidural space from skin, number of attempts, time taken for epidural space localization and quality of the block were the parameter recorded during the study. Results: First attempt success rate for epidural space localization was highest in Group III (100%). The mean time taken for epidural space localization was least in Group III, and when compared with other groups it was found to be statistically significant with P = 0.016. Number of attempt for space localization and success rate of the block was better in the majority of patients of Group III, but the difference was found to be statistically nonsignificant. Complication rate was almost negligible in all three techniques. Conclusion: We conclude that the time taken to localize the epidural space was least in drip infusion technique. As for number of attempts, quality of the block and complications is concerned, all the three techniques are comparable.


Kaur A.D.,Pt. B. D. Sharma | Atreya V.K.,Mahatma Gandhi Medical College and Hospital
Journal of Indian Academy of Forensic Medicine | Year: 2013

The nitrates/nitrites are an important metabolite in the biological nitrogen cycle, and natural constituent of soil and vegetation. Nitrates in commercial use are all of synthetic origin. Nitrite poisoning in fatal cases is commonly seen as an occupational hazard in farmers who use nitrates as fertilizers, pesticides and in this region of Rajasthan (Sanganer) in the dye industry, where it is used as mordent of dye. Dyeing, including block painting is a method which imparts beauty to the textile by applying various colors on to a fabric. Dyeing of Sanganeri Printed Cloth is by use of natural vegetable colors. But with change of times, synthetic products have found their way into the dyeing process. It is estimated that 25% population of Sanganer is directly or indirectly dependent on Sanganeri Print Industries for their livelihood. In this particular case that is discussed here, it was the easy availability of the lethal compound for its use in household dye industries that led to its homicidal use. The mordents used to set dye colour on fabrics to give it, its longevity, curtailed the longevity of life of someone.The nitrates/nitrites are an important metabolite in the biological nitrogen cycle, and natural constituent of soil and vegetation. Nitrates in commercial use are all of synthetic origin. Nitrite poisoning in fatal cases is commonly seen as an occupational hazard in farmers who use nitrates as fertilizers, pesticides and in this region of Rajasthan (Sanganer) in the dye industry, where it is used as mordent of dye. Dyeing, including block painting is a method which imparts beauty to the textile by applying various colors on to a fabric. Dyeing of Sanganeri Printed Cloth is by use of natural vegetable colors. But with change of times, synthetic products have found their way into the dyeing process. It is estimated that 25% population of Sanganer is directly or indirectly dependent on Sanganeri Print Industries for their livelihood. In this particular case that is discussed here, it was the easy availability of the lethal compound for its use in household dye industries that led to its homicidal use. The mordents used to set dye colour on fabrics to give it, its longevity, curtailed the longevity of life of someone.


Yadav P.,Pt. B D Sharma | Aparna,Pt. B D Sharma | Sharma M.,Pt. B D Sharma | Chaudhary U.,Pt. B D Sharma
International Journal of Pharma and Bio Sciences | Year: 2015

Introduction: Hospital diagnostic laboratories investigate many thousands of urine specimens each year, but only a small proportion(about 25-30%) of it are infected. Lot of staff time and culture material are spent on specimens that yield insignificant growth. Therefore, a simple inexpensive test is needed as a preliminary test in routine practice to select those urine samples only which require further examination in the laboratory. Leucocyte esterase test has the advantage of detecting esterases in both intact and lysed leucocytes. Therefore, even specimens that have not been preserved properly will yield a positive test result. Aims & objective: The present study was designed to compare the reliability of wet mount examination and leucocyte esterase activity with that of a urine culture in diagnosing bacteriuria and pyuria in patients of UTIs. Material and Methods: This study was conducted on a total of 600 urine samples received in the Microbiology department, Pt BDS PGIMS, Rohtak. The samples were processed as per standard procedures and subjected to microscopic examination, dipstick testing, TTC test and culture within 30 minutes of sample collection. Result: Of 600 samples 144 were LET positive, of which 106 were positive by urine culture and 38 were urine culture negative. Similarly out of 600 samples 456 were LET negative, of which 417 were negative by urine culture while 39 were positive by urine culture. Out of the 145 culture positives, E. coli (44.1%) was most common pathogen. Conclusion: Rapid dipsticks tests for LET are reliable alternative to culture for screening of UTIs.


Sharma N.,Pt. B. D. Sharma | Singh R.,Pt. B. D. Sharma | Marwah N.,Pt. B. D. Sharma | Gupta S.,Pt. B. D. Sharma | Sen R.,Pt. B. D. Sharma
International Journal of Hematology-Oncology and Stem Cell Research | Year: 2015

Follicular dendritic cells or dendritic reticulum cells are important components of the immune system essential for antigen presentation. Malignancies arising from these cells are uncommon and the first case was reported in 1986. The most common sites of follicular dendritic cell sarcomas are lymph nodes, especially cervical, axillary and mediastinal regions, but extranodal sites including head and neck and gastrointestinal tract may be affected in one-third of patients. Immunohistochemistry plays an important role in its diagnosis to differentiate it from morphologically similar malignancies The present report describes a case of follicular dendritic cell sarcoma in a patient with chronic myeloid leukemia (CML) treated with imatininb mesylate for 6 years. This case deserves reporting due to rarity of the disease and hitherto unreported association with CML. Furthermore, the pathological diagnosis is challenging and requires a close-knit effort between the pathologist and haematologist. © 2015, Tehran University of Medical Sciences (TUMS). All rights reserved.


PubMed | Pt B D Sharma
Type: Journal Article | Journal: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India | Year: 2012

Salivary duct carcinoma (SDC) is a recently described highly malignant tumor, seen most commonly in the parotid gland & occurs in the 6th and 7th decade of life. Rarely, it occurs in the minor salivary glands. The case is presented because of its rare occurrence and unusually presenting as a swelling predominantly involving the maxillary bone. The tumor bears histological homology with breast carcinoma, prostatic carcinoma and sweat duct carcinoma.


PubMed | Pt. B. D. Sharma
Type: Journal Article | Journal: International journal of hematology-oncology and stem cell research | Year: 2015

Follicular dendritic cells or dendritic reticulum cells are important components of the immune system essential for antigen presentation. Malignancies arising from these cells are uncommon and the first case was reported in 1986. The most common sites of follicular dendritic cell sarcomas are lymph nodes, especially cervical, axillary and mediastinal regions, but extranodal sites including head and neck and gastrointestinal tract may be affected in one-third of patients. Immunohistochemistry plays an important role in its diagnosis to differentiate it from morphologically similar malignancies The present report describes a case of follicular dendritic cell sarcoma in a patient with chronic myeloid leukemia (CML) treated with imatininb mesylate for 6 years. This case deserves reporting due to rarity of the disease and hitherto unreported association with CML. Furthermore, the pathological diagnosis is challenging and requires a close-knit effort between the pathologist and haematologist.


Chandi A.,Pt. B. D. Sharma | Sirohiwal D.,Pt. B. D. Sharma | Malik R.,Pt. B. D. Sharma
Archives of Gynecology and Obstetrics | Year: 2015

Background: Hypertensive diseases are directly responsible for 24 % of maternal deaths in India. A screening method is yet to be discovered to reduce the morbidity and mortality related to it. Serum triglyceride (TG) levels are reported to increase in hypertensive pregnant women. Aim: To predict pregnancy-induced hypertension (PIH) by serum triglyceride values. Method: This study is a prospective cohort study that was conducted over three hundred normotensive, primigravida women with singleton pregnancy at 14–20 weeks of gestation. These were divided into two groups on the basis of their TG concentration estimated at 14–20 weeks of gestation. The pregnancy was then followed till delivery and, signs and symptoms of PIH were noted in both the groups. Results: Out of 300 women, 210 women completed the study. Fifty-nine women developed PIH and 151 women remained normotensive. Among 59 women, 45 women had raised TG values i.e., ≥160 mg/dL and 14 women were with normal TG levels i.e., <160 mg/dL. A significant positive correlation was found between serum TG concentration and systolic and diastolic blood pressure. It was observed that a cutoff of 162.50 mg/dL for TG could reliably predict PIH with sensitivity of 76 % and specificity of 85 %. Also, the mothers with hypertriglyceridemia were found to be at higher risk of developing early-onset PIH. Conclusion: Our study supports the evidence that early pregnancy hypertriglyceridemia is associated with an increased risk of PIH. © 2015, Springer-Verlag Berlin Heidelberg.


PubMed | Pt. B. D. Sharma
Type: Journal Article | Journal: Archives of gynecology and obstetrics | Year: 2015

Hypertensive diseases are directly responsible for 24 % of maternal deaths in India. A screening method is yet to be discovered to reduce the morbidity and mortality related to it. Serum triglyceride (TG) levels are reported to increase in hypertensive pregnant women.To predict pregnancy-induced hypertension (PIH) by serum triglyceride values.This study is a prospective cohort study that was conducted over three hundred normotensive, primigravida women with singleton pregnancy at 14-20 weeks of gestation. These were divided into two groups on the basis of their TG concentration estimated at 14-20 weeks of gestation. The pregnancy was then followed till delivery and, signs and symptoms of PIH were noted in both the groups.Out of 300 women, 210 women completed the study. Fifty-nine women developed PIH and 151 women remained normotensive. Among 59 women, 45 women had raised TG values i.e., 160 mg/dL and 14 women were with normal TG levels i.e., <160 mg/dL. A significant positive correlation was found between serum TG concentration and systolic and diastolic blood pressure. It was observed that a cutoff of 162.50 mg/dL for TG could reliably predict PIH with sensitivity of 76 % and specificity of 85 %. Also, the mothers with hypertriglyceridemia were found to be at higher risk of developing early-onset PIH.Our study supports the evidence that early pregnancy hypertriglyceridemia is associated with an increased risk of PIH.

Loading Pt. B. D. Sharma collaborators
Loading Pt. B. D. Sharma collaborators