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Kānpur, India
Kānpur, India
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Mahtab R.,P.S.I.T | Srivastava A.,P.S.I.T | Gupta N.,P.S.I.T | Tripathi A.,P.S.I.T
Journal of Chemical and Pharmaceutical Sciences | Year: 2014

All the newly synthesized benzothiazole derivatives have shown considerable anti-inflammatory activity. In the present research work, we were synthesized a series of novel Benzothiazole derivatives and by using sulfa drugs. The Benzothiazole derivatives such as substituted 2-benzylbenzo[d]thiazole-6- sulfonamide were synthesized from substituted benzyl bromide by scheme 1 & 2. The chemical structures of the synthesized compounds were confirmed by means of IR, 1H-NMR, Mass spectral and elemental analysis. These compounds were screened for anti-inflammatory activity by carrageenan induced paw oedema method in rats at a dose of 100 mg/kg body weight. Among the tested compounds of benzothiazole derivatives, compounds Rm2, Rm3, Rm 5, Rm8 & Rm9 exhibited some anti-inflammatory activity but compounds Rm1, Rm4, Rm 6, Rm7 & Rm10 were more potent when compared to standard drug celecoxib.


Shukla R.K.,Vssd College | Kumar A.,PSIT | Srivastava U.,PSIT | Pandey V.K.,DBS College
International Journal of Thermophysics | Year: 2016

Density and acoustic velocity were measured for binary liquid mixtures of formamide, N-methylacetamide (NMA), dimethylformamide (DMF), and dimethylacetamide (DMA) with acetonitrile at atmospheric pressure and 293.15 K, 298.15 K, 303.15 K, 308.15 K, or 313.15 K over the concentration range 0.12 to 0.97. Models assuming association and nonassociation of the components of the mixtures were used to predict the behavior of the studied liquids, which would typically show weak interactions. The measured properties were fitted to the Redlich–Kister polynomial to estimate the binary coefficients and standard errors. The data were used to study the molecular interactions in the binary mixtures. Furthermore, the McAllister multibody interaction model was used to correlate the properties of the binary liquid mixtures. Testing of the nonassociation and association models for the different systems showed that, compared with the nonassociation model theoretical results, the association model theoretical results were more consistent with the experimental results. © 2016, Springer Science+Business Media New York.


Pal R.S.,PSIT | Pal Y.,PSIT | Singh V.,BBS Institute of Pharmaceutical and Allied science
International Journal of Pharmacy and Technology | Year: 2016

Various studies have already been performed involving the whole aerial parts of Centella asiatica (L.) (Umbelliferae),commonly known as gotukola or jalbrahmi and thus the present investigation has been carried out for the phytochemical study of ethanolic extract of the aerial parts of Centella asiatica. To perform this activity,the drug (1.5kg) was exhaustively extracted in 95% ethanol using Soxhlet apparatus. The column chromatography was performed then for isolating the various phytoconstituents using the solvents of increasing polarity from petroleum ether to methanol. The isolated compounds were structurally elucidated by using various spectral data analysis,i.e.,IR,1H NMR,13C NMR and positive ion FAB MS. One of the isolated compounds was characterized as n-octadecanoic acid. © 2016,International Journal of Pharmacy and Technology. All rights reserved.


Jha S.K.,British Columbia Ministry of forests | Dwivedi A.K.D.,British Columbia Ministry of forests | Tiwari A.,PSIT
2010 IEEE International Conference on Computational Intelligence and Computing Research, ICCIC 2010 | Year: 2010

Open source communities have successfully developed a great deal of software. Due to its free availability and highly secure operating system environment it is promoted by most of the countries all over the world. India also started contributing in this field. Government of India is also promoting usage of Open Source softwares due to its economical feasibility and security. Due to its huge demand in software field a major concern is of its reliability, which is defined as the probability of failure-free software operation for a specified period of time in a given environment. In this paper on the basis of literature survey of open source and reliability, facts regarding Open Source softwares as well as different reliability concepts are elaborated. Important Models to estimate reliability are studied and then main factors are explained here. This paper will be helpful for research scholars doing their research in software reliability. © 2010 IEEE.


Bhaskar J.,Uttar Pradesh Technical University | Haq S.,Uttar Pradesh Technical University | Pandey A.K.,Polymer Processing Laboratory | Srivastava N.,PSIT
Journal of Materials and Environmental Science | Year: 2012

The low maintenance cost of wood plastic composite (WPC) is generating a boom in the market of wood composites products. An attempt is made to fabricate WPCs with saw dust of pine wood flour which is wastages of wood/furniture industry. These composites (WPCs) are made using matrices of recycled polypropylene (rPP) with sawdust (Pine Wood flour) as filler. Corresponding WPCs are also made using virgin plastics (vPP) for comparison with the recycled plastic based composites. All varieties of these WPCs are made through melt compounding and injection moulding with varying formulations based on the plastic type (PP), plastic form (recycled and virgin), wood four content and addition of coupling agent(MAPP). The water absorption and thickness swelling evaluated. To understand the changes in WPCs stability and durability performance, microstructure of the composites are examined, Incorporation of maleated polypropylene (MAPP) coupling agent in composite formulation improved the stability. Scanning electron microscopy (SEM) images of the fractured surfaces of WPCs confirmed that the MAPP coupling improved the interfacial bonding between the plastic and the wood filler for the series of composites.


Dixit A.,PSIT | Jain P.,Indian Institute of Technology Kanpur | McKay D.W.,University of Kansas | Mukherjee P.,State University of New York at Stony Brook
European Physical Journal C | Year: 2010

We explore the possibility that a new-physics interaction can provide an explanation for the knee just above 106 GeV in the cosmic ray spectrum. We model the new-physics modifications to the total proton-proton cross section with an incoherent term that allows for missing energy above the scale of new physics. We add the constraint that the new physics must also be consistent with published pp cross section measurements, using cosmic ray observations, an order of magnitude and more above the knee. We find that the rise in cross section required at energies above the knee is radical. The increase in cross section suggests that it may be more appropriate to treat the scattering process in the black disc limit at such high energies. In this case there may be no clean separation between the standard model and new-physics contributions to the total cross section. We model the missing energy in this limit and find a good fit to the Tibet III cosmic ray flux data. We comment on testing the new-physics proposal for the cosmic ray knee at the Large Hadron Collider. © 2010 Springer-Verlag / Societá Italiana di Fisica.


Monika,Technological Institute of Textile and science | Kumar M.,Technological Institute of Textile and science | Shekhar M.,PSIT
ICROIT 2014 - Proceedings of the 2014 International Conference on Reliability, Optimization and Information Technology | Year: 2014

With the advancement in mobility management in next generation, people will have an effortless, widespread, continuous access to information, activity and communication etc. when, where and how the client want it. To craft such an environment, one calls for integrating various networks that are budding from various emerging engineering practices. The Next Generation Future Network (NGFN) seems to visualize as a cluster of synchronized heterogeneous mobile interacting technologies with a unique Internet Protocol (IP). Thus to make certain about continual services during session handoffs necessitates the implementation of successful mobility and session management mechanisms in these contributing access networks. Furthermore, an efficient and effective distributive system can be valuable in wide range of areas such as: for monitoring the entry to a secure data base, refining QoS, digital media files, concurrent data structure in wireless applications and in mobile ad hoc networks. To achieve seamless mobility management for future networks (FNs), a study of WLAN and WiMAX interworking solution including integration architecture, switching procedure and inter-system measurement has been performed. For the purpose of simulation QualNet Simulator tool has been used. © 2014 IEEE.


Shukla R.K.,Vssd College | Kumar A.,PSIT | Awasthi N.,Vssd College | Srivastava U.,PSIT | Srivastava K.,JSS Academy of Technical Education
Arabian Journal of Chemistry | Year: 2014

Densities and speed of sound were measured for the binary liquid mixtures formed by benzonitrile, chlorobenzene, benzyl chloride and benzyl alcohol with benzene at 298.15, 303.15, 308.15 and 313.15. K and atmospheric pressure over the whole concentration range. Prigogine-Flory-Patterson model (PFP), Ramaswamy and Anbananthan (RS) model and model suggested by Glinski, were utilized to predict the associational behavior of weakly interacting liquids. The measured properties were fitted to Redlich-Kister polynomial relation to estimate the binary coefficients and standard errors. An attempt has also been made to study the molecular interactions involved in the liquid mixture from observed data. Furthermore, the McAllister multi body interaction model was also used to correlate the binary properties. These models were compared and tested for different systems showing that the associated processes yield fair agreement between theory and experiment as compared to non-associated processes. © 2014 King Saud University.


Shukla R.K.,Vssd College | Kumar A.,P.S.I.T. | Srivastava U.,P.S.A.T. | Srivastava K.,Vssd College | Gangwar V.S.,Vssd College
Arabian Journal of Chemistry | Year: 2012

Densities and refractive indices were measured for the binary liquid mixtures formed by formamide, N-methylacetamide, di-methylformamide and di-methylacetamide with acetonitrile at T = 293.15, 298.15, 303.15, 308.15 and 313.15 K and atmospheric pressure over the whole concentration range. Lorentz-Lorentz mixing rule, Ramaswamy and Anbananthan model and model devised by Glinski were used to study the refractive index and molar refractivity. These results have been discussed to study the type of mixing behavior between the mixing molecules. The measured data were fitted to the Redlich-Kister polynomial relation to estimate the binary coefficients and standard errors. Furthermore, McAllister multibody interaction model is used to correlate the binary refractive index with the experimental findings. It is observed that molar refractivity, molecular interaction and association constant can be better understood from these models. © 2012.


Gupta R.,PSIT | Singh V.P.,PSIT
RAECE 2015 - Conference Proceedings, National Conference on Recent Advances in Electronics and Computer Engineering | Year: 2015

Research in medical science is always seeking new technologies which meet the growing demands of better, more stable and durable implant in body environment. An ideal implant should excel in both the basic requirements i.e. in mechanical properties and in biocompatibility. Till now, very few materials can fulfill both the needs. To cope up with the emerging demands, new inventions are always required. Mechanical properties of implant like strength besides adhesion and integration of implant with human tissue is of paramount importance. Recent development in this field led to development of various biocoatings which exhibit enhanced integration of implant with the human tissue. Various recent technologies used in coating of metallic implants are reviewed in this paper. These alternative coating techniques have shown better adhesion to varieties of substrates. Microwave processing is emerging as an innovative technology in efficient, economic, effective manner with many attractive advantages. © 2015 IEEE.

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