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Menlo Park, CA, United States

Della Casa E.,Clinic for Manual Therapy | Della Casa E.,University of Zurich | Affolter Helbling J.,University of Zurich | Affolter Helbling J.,proVITAL | And 3 more authors.
BMC Musculoskeletal Disorders

Background: Head-eye movement control deficit is an identified problem in patients with chronic neck pain, particularly in cases of whiplash associated disorders (WAD). To date, there is no evidence concerning the reliability and validity of visually assessed active head-eye movement control tests. Therefore, the objectives of the present cross-sectional study were, a) to develop a test battery; and b) to investigate inter-observer reliability and discriminative validity in patients with chronic neck pain compared to healthy controls. Methods. The study was conducted at two physiotherapy clinics in Switzerland. Ethics Committee approval was obtained. Ten active head-eye coordination tests, on 23 patients with chronic neck pain and associated symptoms and 19 healthy controls, were videotaped. The tests included eye movements in the neutral head position and 45° relative neck rotation, gaze stability and sequential head-eye movements. All tests were performed in the sitting and standing positions. Two blinded physiotherapists independently rated the randomized videos. Performance was rated as negative, moderately positive or clearly positive. Weighted kappa (wK) and 95% confidence intervals (CI) were calculated to investigate inter-observer reliability. Good reliability was defined as wK >0.5 with a lower boundary of 95% CI >0.2. Odds ratios (to define cut-off points) and the distribution of the classificator, numbers of positive tests, were calculated. Results: Three out of ten tests showed excellent (wK 0.82 to 0.86), five out of ten tests showed substantial (wK 0.69 to 0.79) and two out of ten tests showed moderate (wK 0.54 to 0.59) reliability. Results were comparable in the sitting and standing positions. On average, three out of five tests were rated positive in patients and one out of five tests was rated positive in healthy controls. An odds ratio of 13.3 to 18.6 was obtained using ≥2/5 tests as a cut-off point. Conclusion: Visual assessment by physiotherapists of head-eye movement control tests is reliable. The test battery is able to discriminate between patients with chronic neck pain and healthy controls. There were no differences in performance between the sitting and standing positions. The test battery can therefore be reduced to five tests. Further research is needed to identify the test-retest stability and responsiveness. © 2014 Della Casa et al.; licensee BioMed Central Ltd. Source

proVITAL | Date: 1989-10-05


proVITAL | Date: 2013-02-22

Chemical products used in the cosmetic industry.

Fernandez E.,CSIC - Institute of Advanced Chemistry of Catalonia | Martinez-Teipel B.,proVITAL | Armengol R.,proVITAL | Barba C.,CSIC - Institute of Advanced Chemistry of Catalonia | Coderch L.,CSIC - Institute of Advanced Chemistry of Catalonia
Journal of Photochemistry and Photobiology B: Biology

Hair is exposed every day to a range of harmful effects such as sunlight, pollution, cosmetic treatments, grooming practices and cleansing. The UV components of sunlight damage human hair, causing fibre degradation. UV-B attacks the melanin pigments and the protein fractions (keratin) of hair and UV-A produces free radical/reactive oxygen species (ROS) through the interaction of endogenous photosensitizers. Hair was dyed and the efficacy of two antioxidant formulations was demonstrated after UV exposure by evaluating, surface morphology, protein and amino acid degradation, lipidic peroxidation, colour and shine changes and strength/relaxation properties. UV treatment resulted in an increase in protein and lipid degradation, changes in colour and shine and in adverse consequences for the mechanical properties. Natural antioxidants obtained from artichoke and rice applied to pretreated hair improved mechanical properties and preserved colour and shine of fibres, coating them and protecting them against UV. Furthermore, the lipidic peroxidation of the protein degradation caused by UV was reduced for some treated fibres, suggesting an improvement in fibre integrity. This was more marked in the case of the fibres treated using the artichoke extract, whereas the rice extract was better preserving shine and colour of hair fibres. © 2012 Elsevier B.V. All rights reserved. Source

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