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Gorzów Śląski, Poland

Lacomba M.T.,University of Alcala | Lacomba M.T.,AlcalaUniversity | Del Moral O.M.,Henares Hospital | Coperias Zazo J.L.,Pri Ncipe Of Asturias University Hospital | And 2 more authors.
Clinical Journal of Pain | Year: 2010

Pain after breast cancer therapy is a recognized complication found to have an adverse impact on patient's quality of life, increasing psychosocial distress. In recent years, case reports about myofascial pain syndrome are emerging in thoracic surgery as a cause of postsurgery pain. Myofascial pain syndrome is a regional pain syndrome characterized by myofascial trigger points in palpable taut bands of skeletal muscle that refers pain a distance, and that can cause distant motor and autonomic effects. OBJECTIVE: The objective of this study was to assess the incidence of myofascial pain syndrome prospectively 12 months after breast cancer surgery. METHODS: Each participant was assessed preoperatively, postoperatively between day 3 and day 5, and at 1, 3, 6, and 12 months after surgery. A physical therapist, expert in the diagnosis of myofascial pain syndrome, performed follow-up assessments. Pain descriptions by the patients and pain pattern drawings in body forms guided the physical examination. The patients were not given any information concerning myofascial pain or other muscle pain syndromes. RESULTS: One year follow-up was completed by 116 women. Of these, 52 women developed myofascial pain syndrome (44.8%, 95% confidence interval: 35.6, 54.3). CONCLUSION: Myofascial pain syndrome is a common source of pain in women undergoing breast cancer surgery that includes axillary lymph node dissection at least during the first year after surgery. Myofascial pain syndrome is one potential cause of chronic pain in breast cancer survivors who have undergone this kind of surgery. © 2010 by Lippincott Williams & Wilkins.

Kurlenda J.,Provincial Hospital | Grinholc M.,Medical University of Gdansk
Acta Biochimica Polonica | Year: 2012

Staphylococcus aureus is a common pathogen responsible for health-care-associated infections as well as community acquired ones. It is the etiological factor of a wide spectrum of infections. Therapeutic problems are caused by resistance of S. aureus to many antibiotics, specifically to methicillin (methicillin-resistant S. aureus, MRSA). In such cases a limited spectrum of antibiotics may be used and prolonged hospitalization is costly. Hence, there is an urgent need for the development of alternative antibiotic therapeutics. This work reviews the current knowledge concerning prospective treatment of staphylococcal diseases.

Raba G.,Provincial Hospital | Laudanski P.,Medical University of Bialystok | Kanczuga-Koda L.,Medical University of Bialystok
European Journal of Gynaecological Oncology | Year: 2010

Primary fallopian tube carcinoma is a rare malignancy, representing about 1% of female genital tract malignancies. We present a case report and compare the medical performance with accessible data from the literature as well as present immunohistochemical analysis of estrogen, progesterone, and proliferative together with basic cytokeratin reactions. We found that immunohistochemical expression of ER-β was dominant over ER-α which encourages further evaluations to be performed on a larger number of samples, especially taking into account the very scant progesterone receptor expression we noted. On the basis of the course of disease under study, etiological problems and the possibility of clinical misdiagnosis have been discussed. The low prevalence rate and lack of clear symptoms of this type of carcinoma makes the final clinical diagnosis almost impossible without an intraoperative histopathological study. Multicenter studies are needed to improve the understanding of possible risk factors.

Garcia Vicente A.M.,University of Castilla - La Mancha | Soriano Castrejon A.,University of Castilla - La Mancha | Leon Martin A.,University of Castilla - La Mancha | Chacon Lopez-Muniz I.,Virgen de la Salud Hospital | And 5 more authors.
European Journal of Nuclear Medicine and Molecular Imaging | Year: 2013

Purpose: To determine whether the metabolic features of breast tumours differ among molecular subtypes. Methods: This prospective study included 168 women diagnosed with locally advanced breast cancer. PET/CT was requested in the initial staging before neoadjuvant treatment (multicentre study, FISCAM grant). All patients underwent an 18F-FDG PET/CT scan with a dual time-point acquisition. Both examinations (PET-1 and PET-2) were evaluated qualitatively and semiquantitatively with calculation of SUVmax (SUV-1 and SUV-2, respectively), and the percentage variation in the SUVs and retention indexes (RI) between PET-1 and PET-2 in the breast tumour were calculated. Biological prognostic parameters, including the steroid receptor status, HER-2 expression, proliferation rate (Ki-67) and grading, were determined from primary tumour tissue. Tumour subtypes were classified following the recommendations of the 12th International Breast Conference, by immunohistochemical surrogates as luminal A, luminal B-HER2(-), luminal B-HER2(+), HER2(+) or basal. Metabolic semiquantitative parameters and molecular subtypes were correlated. Results: Of the 168 tumours, 151 were classified: 16 were luminal A, 53 were luminal B-HER2(-), 29 were luminal B-HER2(+), 18 were HER2(+) and 35 were basal. There were significant differences between SUV-1 and SUV-2 and the different subtypes, with higher SUVs in HER2(+) and basal tumours. No significant differences were found with respect to RI. Conclusion: Semiquantitative metabolic parameters showed statistically significant differences among the molecular subtypes of the tumours evaluated. Therefore, there seems to be a relationship between molecular and glycolytic phenotypes. © 2013 Springer-Verlag Berlin Heidelberg.

Raba G.,Provincial Hospital | Raba G.,University of Rzeszow
Wideochirurgia I Inne Techniki Maloinwazyjne | Year: 2014

Internal iliac artery ligation has been a valued method of treating postpartum haemorrhage saving women's fertility. It is considered as an irreversible procedure with no possibility of recanalisation. The manuscript concerns a case of unilateral recanalisation of the hypogastric artery after ligation as a method of postpartum haemorrhage treatment. Material: 24 year old woman with body mass index 28 kg/ m2 with ligated internal iliac arteries due to postpartum haemorrhage. In the place of surgical ligation, the partial recanalisation of the internal iliac artery was noticed. Five mm under the narrowing there was found the telectasis of vessel's diameter with turbulent blood flow and contrast back. There can occur partial recanalization in the ligated internal iliac artery after obliteration in postpartum haemorrhage treatment. Exfoliation of endothelium shows that the process of recanalisation may be a risk factor of further complications of internal iliac artery ligation.

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