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Bottrop, Germany

Nazaradeh F.,Proth O Type GmbH
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference | Year: 2012

The human larynx is a versatile organ. Main functions are phonation, protection and regulation of the air ways. Patients suffer severely from the diagnosis of a laryngeal carcinoma of the stages T3 and T4. In most cases this diagnosis will lead to a total laryngectomy, which is usually dissatisfying in the sense of postoperative rehabilitation. The postoperative consequences include the loss of the native voice, the loss of regular air ways via mouth and nose, sense of smell, and the inability to build up an abdominal pressure. In this paper we focus on the feasibility of a modular larynx prosthesis which enables the laryngectomee to talk with his native voice, to breathe via the regular air ways, and to build up abdominal pressure. In particular we will give insights for a postoperative solution - a modular prosthesis based on a biomimetic self-regulating double clack-valve and on a voice reconstruction module, a so called vocoder. The vocoder is a device to reproduce the natural human voice. Most important for the use is an additional device required to analyze, conserve and manage voice characteristics of the patient before surgery. The self-regulating double clack-valve is designed to build up an abdominal pressure e.g. to cough. Therefore, our valve-system is working in both directions - a two-way valve system. By bridging the gap of the regular air ways lost by laryngectomy, the sense of smell and taste are restored. In the following we will present details and characteristics of these two main components required for a modular prosthesis of the larynx in laryngectomees. Source


Kelterer W.,Fraunhofer Institute for Biomedical Engineering | Kelterer W.,Bremen University of Applied Sciences | Dorge T.,Fraunhofer Institute for Biomedical Engineering | Dupre M.,Proth O Type GmbH | And 5 more authors.
Biomedizinische Technik | Year: 2011

The human larynx is a miscellaneous organ, which main functions are phonation, protection, and regulation of the air ways. The VF and the FVF make up the laryngeal double valve that is required for the ability of building up the abdominal prelum. With the loss of the larynx, the person concerned suffers from many handicaps, amongst others, the disability to build up abdominal pressure. The development of a self-regulating double clack valve for a functional laryngeal prosthesis is the subject of this thesis. The valve was designed to imitate the laryngeal double valve function. A model with a narrow and a wide inlet was built to abstract the larynx and its vocal folds and false vocal folds as clacks. When using the narrow inlet model, it was shown, that the FVC were closed during expiration, whereas the VC were closed during inspiration. Whereas using the wide inlet demonstrated that the VC were closed during expiration and the FVC were closed during inspiration. To simulate fluid flow the angle of the VC and of the FVC, the distance between both clacks and the flow rate were altered against each other. During certain simulations vortices were built between the clacks, which build up pressure upon the particular clack and initiated the closure. Vortices occurred significantly more often during simulations with a narrow inlet than a wide one. The developed "two way clack valve" was shown to be working well while using the narrow inlet. Furthermore the narrow inlet model describes the natural conditions in the human larynx more appropriate than the wide one. The designed valve represents a fundament for future work on the functional laryngeal prosthesis. © 2011 by Walter de Gruyter Berlin Boston. Source


Nazaradeh F.,Proth O Type GmbH | Dupre M.A.,Proth O Type GmbH | Doerge T.,Fraunhofer Institute for Biomedical Engineering | Eckermann C.,Proth O Type GmbH | And 2 more authors.
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS | Year: 2012

The human larynx is a versatile organ. Main functions are phonation, protection and regulation of the air ways. Patients suffer severely from the diagnosis of a laryngeal carcinoma of the stages T3 and T4. In most cases this diagnosis will lead to a total laryngectomy, which is usually dissatisfying in the sense of postoperative rehabilitation. The postoperative consequences include the loss of the native voice, the loss of regular air ways via mouth and nose, sense of smell, and the inability to build up an abdominal pressure. In this paper we focus on the feasibility of a modular larynx prosthesis which enables the laryngectomee to talk with his native voice, to breathe via the regular air ways, and to build up abdominal pressure. In particular we will give insights for a postoperative solution - a modular prosthesis based on a biomimetic self-regulating double clack-valve and on a voice reconstruction module, a so called vocoder. The vocoder is a device to reproduce the natural human voice. Most important for the use is an additional device required to analyze, conserve and manage voice characteristics of the patient before surgery. The self-regulating double clack-valve is designed to build up an abdominal pressure e.g. to cough. Therefore, our valve-system is working in both directions - a two-way valve system. By bridging the gap of the regular air ways lost by laryngectomy, the sense of smell and taste are restored. In the following we will present details and characteristics of these two main components required for a modular prosthesis of the larynx in laryngectomees. © 2012 IEEE. Source

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