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Dinca O.,Prof Dr Dan Theodorescu Clinical Hospital For Oro Maxillo Facial Surgery | Dinca O.,University of Bucharest | Zurac S.,University of Bucharest | Staniceanu F.,University of Bucharest | And 6 more authors.
Romanian Journal of Morphology and Embryology | Year: 2014

The authors report their experience using platelet-rich fibrin (PRF) therapy for the treatment of ten patients presenting bisphosphonaterelated osteonecrosis of the jaw (BRONJ). The aim of our study was to evaluate the effect of this therapy on recurrent BRONJ and to describe the clinical and histopathological/immunohistochemical staining features of PRF treatment. As such, we describe the method we used and report the results observed in the areas treated as well as side effects. The reported results recommend the safety and efficacy of PRF in treatment of BRONJ. © 2014, Editura Academiei Romane. All rights reserved.


Dinca O.,Prof Dr Dan Theodorescu Clinical Hospital For Oro Maxillo Facial Surgery | Severin E.,Carol Davila University of Medicine and Pharmacy | Vladan C.,Prof Dr Dan Theodorescu Clinical Hospital For Oro Maxillo Facial Surgery | Bodnar D.C.,Carol Davila University of Medicine and Pharmacy | Bucur A.,Prof Dr Dan Theodorescu Clinical Hospital For Oro Maxillo Facial Surgery
Romanian Journal of Morphology and Embryology | Year: 2014

Cherubism is a familial benign fibro-osseous disease of the jaws. On radiography, the lesions exhibit bilateral multinuclear radiolucent areas. Histopathology reveals multinucleated giant cells in the background of proliferating fibrous connective tissue. Mutations in the SH3BP2 gene are identified as the cause of cherubism. A 12-year-old girl with prominence of the lower face was investigated. Her chief complaint was her facial appearance with asymmetrical swelling of the cheeks. Clinical and radiographic examinations, and biopsy, biochemical analysis and genetic investigations were performed.

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