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Halle An Der Saale, Germany

Patent
Probiodrug | Date: 2015-09-03

Novel diagnostic assays for the diagnosis of amyloidosis, in particular Alzheimers disease, and related aspects. In particular, monoclonal antibodies and an antibody assay are provided.


Patent
Probiodrug | Date: 2015-09-23

The invention relates to novel pyrrolidine derivatives of formula (I): wherein R


Patent
Probiodrug | Date: 2014-03-14

The invention relates to a compound of formula (I) or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof, wherein R


Radiolabeled glutaminylcyclase (QC) inhibitors as imaging agents, in particular, but not exclusively, as medical imaging agents for the detection of neurological disorders; and pharmaceutical compositions, methods and kits for detecting neurological disorders, using the radiolabeled inhibitors.


Patent
Probiodrug | Date: 2013-02-26

Novel crystal structures of human and murine glutaminyl cyclase (QC, EC 2.3.2.5), methods of preparing the crystals, as well as the use of said crystal structures for identifying inhibitors of human and murine glutaminyl cyclase.

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