Priyadarshini Institute of Engineering and Technology

Nāgpur, India

Priyadarshini Institute of Engineering and Technology

Nāgpur, India
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Suke S.G.,Priyadarshini Institute of Engineering and Technology | Negi H.,Fresenius Kabi Oncology Ltd | Negi H.,University of Delhi | Mediratta P.K.,University of Delhi | And 2 more authors.
European Journal of Pharmacology | Year: 2013

The aim of the present study was to evaluate the effect of combined treatment of pioglitazone (PGZ) and prednisolone (PDL) on the progression of adjuvant-induced arthritis in rats. Adjuvant arthritis was induced by single intra-dermal injection of 0.1 ml Freund's complete adjuvant (0.05% w/v Mycobacterium butyricum in mineral oil) into foot pads of left hind paws of Wistar rats of either sex. There were six experimental groups: Group I was healthy animals as control, Group II was arthritic animals without drug treatment, Group III was arthritic animals treated with a standard non-steroidal anti-inflammatory drug aspirin (100 mg/kg), Group IV was arthritic animals received PGZ (10 mg/kg) alone, Group V was arthritic animals received PDL (10 mg/kg) alone, and Group VI was arthritic animals treated with a combined suspension of PGZ and PDL (20 mg/kg). Drugs were administered daily orally at day 0 and continued upto 28th day after induction of arthritis. Induction of arthritis significantly increased hind paw volume (HPV), loss of body weight (BW), enhanced tibiotarsal joint thickness (TJT), and increased plasma tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-6 levels. Treatment with aspirin or combined suspension of PGZ and PDL in the arthritic animals produced significant reductions in HPV and TJT, normalized BW, and significantly decreased plasma levels of TNF-α and IL-6. These observations suggest that the combined administration of PGZ and PDL was effective in modulating the inflammatory response and suppress arthritis progression in experimental animal model. These findings may help to improve the treatment of rheumatoid arthritis. © 2013 Published by Elsevier B.V. All rights reserved.


Dontulwar J.,Priyadarshini Institute of Engineering and Technology
International Journal of Pharmaceutical Sciences Review and Research | Year: 2015

A new terpolymer resin was synthesized from 1-Naphthol-4-sulphonic acid and Hexamethylene diamine with formaldehyde by polycondensation method in an acidic medium with molar proportion of reactants (1:1:2). To reveal the structure of the resin, the resin was characterized by elemental analysis and spectral methods, i.e. composition of terpolymer has been determined in the basis of their elemental analysis. The terpolymer resin has been characterized by UV-Visible, FT-IR and NMR (1H & 13C) spectra. The number average molecular weight has been determined by conductometric titration in non-aqueous medium. The structure of the terpolymer resin was confirmed on the basis of spectral data. © 2015, Global Research Online. All rights reserved.


Birajdar G.K.,Priyadarshini Institute of Engineering and Technology | Mankar V.H.,Government Polytechnic
Digital Investigation | Year: 2013

Today manipulation of digital images has become easy due to powerful computers, advanced photo-editing software packages and high resolution capturing devices. Verifying the integrity of images and detecting traces of tampering without requiring extra prior knowledge of the image content or any embedded watermarks is an important research field. An attempt is made to survey the recent developments in the field of digital image forgery detection and complete bibliography is presented on blind methods for forgery detection. Blind or passive methods do not need any explicit priori information about the image. First, various image forgery detection techniques are classified and then its generalized structure is developed. An overview of passive image authentication is presented and the existing blind forgery detection techniques are reviewed. The present status of image forgery detection technique is discussed along with a recommendation for future research. © 2013 Elsevier Ltd. All rights reserved.


Sayyad S.Y.,Priyadarshini Institute of Engineering and Technology | Wankhede U.S.,G.H. Raisoni College of Engineering
International Conference on Emerging Trends in Engineering and Technology, ICETET | Year: 2016

Two methods of refrigeration-good Coefficient of performance Vapour compression refrigeration method with good inside temperature control Thermoelectric refrigeration method are combined together in a single setup. The heat fluxes generated from the thermoelectric system are utilized by the vapour compression refrigeration system during the phase transformation of the refrigerant into the evaporator coil before entering into the compressor. System performance of the hybrid experimental setup is compared with Vapour Compression refrigeration operated system. The COP of thermoelectric system in combined with VCRS is increased by proper heat dissipation, from hot side of the peltier units and these heat fluxes utilized by VCRS for its own benefit. © 2015 IEEE.


Katkar M.A.,Priyadarshini Institute of Engineering and Technology | Rao S.N.,Priyadarshini Institute of Engineering and Technology | Juneja H.D.,Rashtrasant Tukadoji Maharaj Nagpur University
RSC Advances | Year: 2012

The green epoxidation of 1-hexene using [hydrazine-N-salicylidene-N′- salicyloyl-] cis-dioxomolybdenum(vi) and its zeolite-Y composite as catalyst in DMF in the presence of molecular oxygen as oxidant and in the temperature range 333-363 K is reported. The 'green' factor of olefin oxidation catalysis using the Mo(vi) dioxo complex is its ability to use atmospheric oxygen which is non-hazardous and inexpensive and produces no harmful by-products. The effects of the initial concentration of the substrate and Mo complex and the temperature in the range 333-363 K on the rate of reaction are examined. The olefin conversion into different products is monitored using gas chromatography. The formation of 1,2-epoxyhexane, 1-hexanal and 2-hexanone is observed under both homogeneous and heterogeneous catalytic conditions; however, 2-hexanone did not form during the reactions using the zeolite composite. 1-Hexene conversion was found to be nearly complete and the product distribution into 1,2-epoxyhexane, 1-hexanal and 2-hexanone being 1:20:6 under homogeneous conditions for 6 h; while the final product is 1-hexanal under heterogeneous conditions for 6 h. The rate of 1-hexene oxidation showed first order dependence with respect to the catalyst and substrate concentration and it was an endothermic reaction (activation energy, 10.68 Kcal mol-1). A tentative mechanism for the oxidation of 1-hexene is proposed and the observed product formation was reasoned to involve epoxide isomerisation through participation of adventitious water in the reaction mixture and the resulting carbonium ions.© 2012 The Royal Society of Chemistry.


Gurnule W.B.,Kamla Nehru Mahavidyalaya | Mandavgade S.K.,Priyadarshini Institute of Engineering and Technology
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2014

The copolymer resin 4-HACF has been synthesized by the condensation of 4-hydroxyacetophenone (4-HA) and catechol (C) with formaldehyde (F) in 1:1:2 molar ratios in presence of 2M hydrochloric acid as catalyst. UV-Visible, IR and proton NMR spectral studies have been carried out to elucidate the structure of the resin. Electrical conductivity measurements have been carried out to ascertain the semiconducting nature of the copolymer resin. The electrical properties of 4-HACF copolymer were measured over a wide range of temperature (313-428K), activation energy of electrical conduction has been evaluated and plot of log α vs 1000/T is found to be linear over a wide range of temperature, which can be ranked it as semiconductor. This remarkable property of this copolymer resin may be used to make a wide range of semiconducting and electronic devices such as transistors, light emitting diodes, solar cells and even lasers which can be manufactured by much simpler way than conventional inorganic semiconductors. Scanning electron microscopy (SEM) was used to determine the surface features of the resin.


Shrivastava S.,Priyadarshini Institute of Engineering and Technology | Rao S.N.,Priyadarshini Institute of Engineering and Technology
Clean - Soil, Air, Water | Year: 2011

A simple, low cost, highly effective, and useful Fenton oxidation treatment of synthetic dye bath waste with pickling liquor as a source of iron (Fe 2+ catalyst) is reported. Optimizations of contact time, Fe 2+ and H 2O 2 doses are carried out. Oxidative de-colorization and degradation of Reactive Blue 4 and Reactive Orange 16 was measured in terms of decrease in absorbance at their wavelength of maximum absorption (RB4, 599nm; and RO16, 493nm) and also as reduction in chemical oxygen demand (COD). Approximately, 62% COD was removed in 2h at optimized doses of Fe 2+ (8.95mM) and H 2O 2 (61.8mM) by using pickling waste as a source of Fe 2+ catalyst. Similar performance efficiency was observed when neat FeSO 4 was used as a source of Fe 2+, indicating that pickling liquor can be a low cost source of Fe 2+ to treat synthetic dye bath waste by Fenton method. The feasibility of the Fenton oxidation process mediated by Fe 2+ present in pickling waste for the de-colorization and degradation of RB4 and RO16 in simulated dye bath wastewater could be demonstrated. Therefore, pickling liquor may emerge as a low cost alternative to expensive FeSO 4 in Fenton oxidation. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Dontulwar J.R.,Priyadarshini Institute of Engineering and Technology
Der Pharma Chemica | Year: 2014

A novel ecofriendly polymer synthesized using starch, glycerol, sorbitol and maleic anhydride was found to be biodegradable having BOD to COD Ratio 0.6075(1). After ensuring its biodegradability and HLB Ratio we have decided to use it for the detergent formulation. Few formulations based on dolomite, polymer combination were formulated. These polymer dolomite detergent combination have shown good performance characteristics as for as reduction in surface tension of water, foam volume and percent detergency is concerned.


Dontulwar J.R.,Priyadarshini Institute of Engineering and Technology
Der Pharma Chemica | Year: 2013

Various liquid detergents were formulated using ecofriendly polymer of mixed carbohydrate and glycol origin. The samples were showing excellent results in terms of performance like reduction in surface tension of water, foam volume and percent detergency. The samples have shown remarkably good performance at par with conventional samples of petroleum origin.


Pandey A.,Priyadarshini Institute of Engineering and Technology
International Journal of Pharma and Bio Sciences | Year: 2015

Turmeric is the common name used for dried rhizome of Curcuma longa L., a monocotyledonous plant belonging to the family Zingiberaceae. Curcumin is responsible for the biological actions of turmeric and comprises of curcumin, demethoxy curcumin and bis demethoxy curcumin. Generally, the commercially produced curcumin is a mixture of the above with curcumin as the main constituent. Turmeric powder, curcumin and its derivatives and many other extracts from the rhizome were found to be bioactive. Tissue culture, an important area of biotechnology can be used to improve the productivity of planting material through enhanced availability of identified planting stock with desired traits.

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