Private Sema Hospital

Erbil, Iraq

Private Sema Hospital

Erbil, Iraq

Time filter

Source Type

Iskurt A.,Yildiz Technical University | Becerikli Y.,Kocaeli University | Mahmutyazicioglu K.,Private Sema Hospital
Journal of Magnetic Resonance Imaging | Year: 2011

Purpose: To demonstrate a novel automatic slice-positioning technique based on three new anatomical landmarks and to standardize prospective scans by lowering rotational and translational variances. Materials and Methods: After defining the interpeduncular fossa corner and the eyeball centers as landmarks, they are manually labeled on 25 different T1 MRI scans. New scans are produced according to the Eyeball centers-Mesencephalon (EM) plane. The comparison of angular deviations at EM and original scans is based on the comparison of rotational angles according to manually labeled Talairach points on both scans. The same variability comparison is also done with automatically captured landmarks to see the effects of segmentation errors. Results: Analysis of variances proved significant lowering of intersubject variability for pitch and yaw angles (P pitch < 0.005, P yaw < 0.001), which are the two basic causes of misalignments. Automatic segmentation accuracy is proved by paired t-test and significance tests. Conclusion: A new field of view and slice orientation proposed by the EM technique will have fixed the follow-up scans by significantly lowering the rotational and translational variances. The EM technique will precisely match the intrasubject scans and produce better standardized intersubject scans. The distinguishing features of landmarks are sufficient for robust automatic capture. © 2011 Wiley-Liss, Inc.


Iskurt A.,Technical University of Istanbul | Becerikli Y.,Kocaeli University | Mahmutyazicioglu K.,Private Sema Hospital
2013 47th Annual Conference on Information Sciences and Systems, CISS 2013 | Year: 2013

While visualizing three dimensional (3D) structure of the coronary arteries, the projectory X-ray images can produce 3D tree of them up to a certain accuracy level with a lower dose of radiation when compared to computer tomography (CT). Here, in this study a novel and complete automatic system is designed which covers preprocessing, segmentation, matching and reconstruction steps for that purpose. First an automatic and novel pattern recognition technique is applied for the extraction of the bifurcation points with their diameters recorded in a map. Then, a novel optimization algorithm is run for matching the branches based on that map and the epipolar geometry of stereopsis. Finally, cut branches are fixed one by one at the bifurcations for completing the 3D reconstruction. The method favors the similar ones in the literature with this novelty since it inherently prevents the wrong overlapping of branches. Other essential problems like correct detection of bifurcation, detection of the true calibration parameters and fast overlapping of matched branches are addressed at acceptable levels. The precision of bifurcation extraction is high at 97% with 96% sensitivity. Accuracy of the vessel centerlines has root-mean-square (rms) error smaller than 0.5 mm for 10 different patients. For phantom model, rms error is 0.75 ± 0.8 mm in 3D localization. © 2013 IEEE.


Koyuncu H.,Yeditepe University | Serefoglu E.C.,Tulane University | Karacay S.,Yeditepe University | Ozdemir A.T.,Ankara Nuclear Research And Training Center | And 2 more authors.
Central European Journal of Urology | Year: 2014

Introduction Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (ME) is nocturnal bed wetting, without any daytime symptoms. Recent clinical studies report an association between lifelong PE and ME. The purpose of this study was to compare the intravaginal ejaculatory time (IELT) between lifelong PE in men with and without ME. The goal was to determine if there is an association between the severity of ME and of IELT. Material and methods A total of 137 men with lifelong PE were included in this study. Subjects were asked if they had childhood ME. The characteristics and mean IELTs of patients with and without ME were compared using the student's t-test, and the correlation between severity of ME and IELT was assessed with trend test. Results Of the 137 lifelong PE patients, 57 reported ME. There was a strong negative correlation in patients with ME between the severity of enuresis and IELT, with IELT being shorter in patients with severe ME. Conclusions A strong correlation between IELT and the severity of ME suggests a common underlying mechanism. Further studies are required to confirm these findings and elucidate the exact pathophysiology.


PubMed | Private Sema Hospital, Yeditepe University, Tulane University and Ankara Nuclear Research And Training Center
Type: Journal Article | Journal: Central European journal of urology | Year: 2014

Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (ME) is nocturnal bed wetting, without any daytime symptoms. Recent clinical studies report an association between lifelong PE and ME. The purpose of this study was to compare the intravaginal ejaculatory time (IELT) between lifelong PE in men with and without ME. The goal was to determine if there is an association between the severity of ME and of IELT.A total of 137 men with lifelong PE were included in this study. Subjects were asked if they had childhood ME. The characteristics and mean IELTs of patients with and without ME were compared using the students t-test, and the correlation between severity of ME and IELT was assessed with trend test.Of the 137 lifelong PE patients, 57 reported ME. There was a strong negative correlation in patients with ME between the severity of enuresis and IELT, with IELT being shorter in patients with severe ME.A strong correlation between IELT and the severity of ME suggests a common underlying mechanism. Further studies are required to confirm these findings and elucidate the exact pathophysiology.


Hosoglu S.,Dicle University | Hosoglu S.,Ishik University | Ahmad Z.,Private Sema Hospital | Tahseen M.S.,Private Sema Hospital | And 3 more authors.
Journal of Infection in Developing Countries | Year: 2014

Introduction: The current status of percutaneous injury and mucous exposures (PMEs) of hospital workers and factors associated with the injuries have not been studied in Iraq. This study aimed to evaluate the epidemiology of PMEs with blood or body fluids that leads serious risks for healthcare workers (HCWs).Methodology: An analytic, cross-sectional survey study was conducted among HCWs in Erbil city center, Iraq. The study was performed at sevenhospitals, and 177 participants were included. The dependent variable was the occurrence of PMEs in the last year, and the independent variables were age, sex, occupation of HCWs, working site, and work duration.Results: A total of 177 HCW participants included 57 nurses/midwives (32.2%), 59 doctors (33.3%), 27 laboratory workers (15.3%), and 34 paramedics/multipurpose workers (19.2%) from seven hospitals. The study concluded that 67.8% of the participants reported at least one occupational PME in the last year. In all, 13.3/person/year PME incidents were reported for nurses, 9.74/person/year for paramedics/multipurpose workers, 6.71/person/year for doctors, and 3.37/person/year laboratory workers. The mean number of PME incidents was 8.91/person/year. HCWs showed 85.0% compliance with wearing mask in risky situations. The most dangerous action for occupational exposure was blood taking (39.0%). In the univariate analysis, none of the investigated variables were found to be significantly related to PME.Conclusions: Occupational injuries and exposures in Iraqi HCWs are extremely common; awareness about protection is not sufficient. Nurses were found to be the highest risk group among HCWs. Preventive actions should be taken to avoid infection. © 2014 Hosoglu et al.


Tomur A.,Private Sema Hospital | Kanter M.,Trakya University | Gurel A.,Private Sema Hospital | Erboga M.,Trakya University
Journal of Molecular Histology | Year: 2011

The aim of this study was to evaluate the possible protective effects of caffeic acid phenethyl ester (CAPE) against cholestatic oxidative stress and liver damage in the common bile duct ligated rats. A total of 18 male Sprague-Dawley rats were divided into three groups: control, bile duct ligation (BDL) and BDL + received CAPE; each group contain 6 animals. The rats in CAPE treated groups were given CAPE (10 μmol/kg) once a day intraperitoneally (i.p) for 2 weeks starting just after BDL operation. The changes demonstrating the bile duct proliferation and fibrosis in expanded portal tracts include the extension of proliferated bile ducts into lobules, inflammatory cell infiltration into the widened portal areas were observed in BDL group. Treatment of BDL with CAPE attenuated alterations in liver histology. The proliferating cell nuclear antigen and the activity of TUNEL in the BDL were observed to be reduced with the QE treatment. The application of BDL clearly increased the tissue hydroxyproline (HP) content, malondialdehyde (MDA) levels and decreased the antioxidant enzyme (superoxide dismutase (SOD), glutathione peroxidase (GPx)) activities. CAPE treatment significantly decreased the elevated tissue HP content, and MDA levels and raised the reduced of SOD, and GPx enzymes in the tissues. The data indicate that CAPE attenuates BDL-induced cholestatic liver injury, bile duct proliferation, and fibrosis. The hepatoprotective effect of CAPE is associated with antioxidative potential. © 2011 Springer Science+Business Media B.V.


Kerman M.,Private Sema Hospital | Kanter M.,Trakya University | Coskun K.K.,Private Sema Hospital | Erboga M.,Trakya University | Gurel A.,Private Sema Hospital
Journal of Molecular Histology | Year: 2012

The aim of this study was to evaluate the therapeutic efficacy of caffeic acid phenethyl ester (CAPE)with an experimental traumatic brain injury (TBI) model in rats. Twenty-four adult male Sprague-Dawley rats were randomly divided into three groups of 8 rats each: control, TBI, and TBI + CAPE treatment. In TBI and TBI + CAPE treatment groups, a cranial impact was delivered to the skull from a height of 7 cmat a point just in front of the coronal suture and over the right hemisphere. Ratswere sacrificed at 4 h after the onset of injury. Brain tissues were removed for biochemical and histopathological investigation. To date, no biochemical and histopathological changes of neurodegeneration in the frontal cortex after TBI in rats by CAPE treatment have been reported. The TBI significantly increased tissue malondialdehyde (MDA) levels, and significantly decreased tissue superoxide dismutase (SOD) and glutathione peroxidase (GP x) activities, but not tissue catalase (CAT) activity, when compared with controls.The administration of a single dose of CAPE (10 μmol/kg) 15 min after the trauma has shown protective effect via decreasing significantly the elevated MDA levels and also significantly increasing the reduced antioxidant enzyme (SOD and GPx) activities, except CAT activity. In the TBI group, severe degenerative changes, shrunken cytoplasma and extensively dark picnotic nuclei in neurons, as well as vacuolization indicating tissue edema formation. The morphology of neurons in theCAPE treatment group waswell protected. The number of neurons in the trauma alone group was significantly less than that of both the control and TBI +CAPE treatment groups. The caspase 3 immunopositivity was increased in degenerating neurons of the traumatic brain tissue. Treatment of CAPE markedly reduced the immunoreactivity of degenerating neurons. TBI caused severe degenerative changes, shrunken cytoplasma, severely dilated cisternae of endoplasmic reticulum, markedly swollen mitochondria with degenerated cristae and nuclear membrane breakdown with chromatin disorganization in neurons of the frontal cortex. In conclusion, the CAPE treatment might be beneficial in preventing trauma-induced oxidative brain tissue damage, thus showing potential for clinical implications.We believe that further preclinical research into the utility of CAPE may indicate its usefulness as a potential treatment on neurodegeneration after TBI in rats. © Springer Science+Business Media B.V. 2011.


PubMed | Private Sema Hospital
Type: Journal Article | Journal: Journal of molecular histology | Year: 2012

The aim of this study was to evaluate the therapeutic efficacy of caffeicacid phenethyl ester (CAPE) with an experimental traumatic brain injury (TBI) model in rats. Twenty-four adult male Sprague-Dawley rats were randomly divided into three groups of 8 rats each: control, TBI, and TBI+CAPE treatment. In TBI and TBI+CAPE treatment groups, a cranial impact was delivered to the skull from a height of 7cm at a point just in front of the coronal suture and over the right hemisphere. Rats were sacrificed at 4h after the onset of injury. Brain tissues were removed for biochemical and histopathological investigation. To date, no biochemical and histopathological changes of neurodegeneration in the frontal cortex after TBI in rats by CAPE treatment have been reported. The TBI significantly increased tissue malondialdehyde (MDA) levels, and significantly decreased tissue superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities, but not tissue catalase (CAT) activity, when compared with controls. The administration of a single dose of CAPE (10mol/kg) 15min after the trauma has shown protective effect via decreasing significantly the elevated MDA levels and also significantly increasing the reduced antioxidant enzyme (SOD and GPx) activities, except CAT activity. In the TBI group, severe degenerative changes, shrunken cytoplasma and extensively dark picnotic nuclei in neurons, as well as vacuolization indicating tissue edema formation. The morphology of neurons in the CAPE treatment group was well protected. The number of neurons in the trauma alone group was significantly less than that of both the control and TBI +CAPE treatment groups. The caspase 3 immunopositivity was increased in degenerating neurons of the traumatic brain tissue. Treatment of CAPE markedly reduced the immunoreactivity of degenerating neurons. TBI caused severe degenerative changes, shrunken cytoplasma, severely dilated cisternae of endoplasmic reticulum, markedly swollen mitochondria with degenerated cristae and nuclear membrane breakdown with chromatin disorganization in neurons of the frontal cortex. In conclusion, the CAPE treatment might be beneficial in preventing trauma-induced oxidative brain tissue damage, thus showing potential for clinical implications. We believe that further preclinical research into the utility of CAPE may indicate its usefulness as a potential treatment on neurodegeneration after TBI in rats.


Sahin C.,Private Sema Hospital | Toraman A.R.,Health Service | Kalkan M.,Private Sema Hospital
European Journal of General Medicine | Year: 2011

Aim: In this study we evaluated cases referred to our clinic with serious complications of circumcision which needed secondary surgical intervention. Method: Between 1995 and 2010, 38 complicated circumcision cases were evaluated. The circumcisions were done at various medical clinics, home or communal circumcision ceremonies held in villages. The patients in the sample ranged in age from five to 24 (average 14). Partial or total glandular amputation, urethral injury, glandular necrosis and preputio-glandular fusion were present in 9, 11, 2, and 16 cases respectively. Result: The incomplete glans was patched with buccal mucosa in all 9 of the cases with glandular amputations. Five of the cases with urethral fistula had simple fistula and these were repaired with a simple closure method. Complete open distal urethra present in the other 6 cases were covered in the duplay style and a hypospadias repair was performed on them with a tubular incised plate urethroplasty technique with buccal mucosa as a patch graft. Both cases with glandular necrosis were put under hyperbaric oxygen treatment. Adhesion freeing and revision were performed to all the cases with preputioglandular fusion Conclusion: Circumcision is the most common surgical procedure in our country. However, since circumcisions are also commonly performed by inexperienced individuals at home, in hospitals and during communal circumcisions where high numbers of circumcisions are performed in a short period time, we frequently come across complications of circumcision.


PubMed | Private Sema Hospital
Type: Journal Article | Journal: Journal of molecular histology | Year: 2011

The aim of this study was to evaluate the possible protective effects of caffeic acid phenethyl ester (CAPE) against cholestatic oxidative stress and liver damage in the common bile duct ligated rats. A total of 18 male Sprague-Dawley rats were divided into three groups: control, bile duct ligation (BDL) and BDL + received CAPE; each group contain 6 animals. The rats in CAPE treated groups were given CAPE (10 mol/kg) once a day intraperitoneally (i.p) for 2 weeks starting just after BDL operation. The changes demonstrating the bile duct proliferation and fibrosis in expanded portal tracts include the extension of proliferated bile ducts into lobules, inflammatory cell infiltration into the widened portal areas were observed in BDL group. Treatment of BDL with CAPE attenuated alterations in liver histology. The proliferating cell nuclear antigen and the activity of TUNEL in the BDL were observed to be reduced with the QE treatment. The application of BDL clearly increased the tissue hydroxyproline (HP) content, malondialdehyde (MDA) levels and decreased the antioxidant enzyme (superoxide dismutase (SOD), glutathione peroxidase (GPx)) activities. CAPE treatment significantly decreased the elevated tissue HP content, and MDA levels and raised the reduced of SOD, and GPx enzymes in the tissues. The data indicate that CAPE attenuates BDL-induced cholestatic liver injury, bile duct proliferation, and fibrosis. The hepatoprotective effect of CAPE is associated with antioxidative potential.

Loading Private Sema Hospital collaborators
Loading Private Sema Hospital collaborators