Anil S.,Prince Sattam Bin Abdulaziz University
Asian Pacific journal of cancer prevention : APJCP | Year: 2016
BACKGROUND: Oral cancers account for approximately 2% of all cancers diagnosed each year; however, the vast majority (80%) of the affected individuals are smokers whose risk of developing a lesion is five to nine times greater than that of non-smokers. Tobacco smoke contains numerous carcinogens that cause DNA damage, including oxidative lesions that are removed effectively by the base-excision repair (BER) pathway, in which poly (ADP-ribose) polymerase 1 (PARP-1), plays key roles. Genetic variations in the genes encoding DNA repair enzymes may alter their functions. Several studies reported mixed effects on the association between PARP-1 variants and the risk of cancer development. Till now no reported studies have investigated the association between PARP-1 variants and oral squamous cell carcinoma (OSCC) risk in an Indian population.MATERIALS AND METHODS: In the present case control study 100 OSCC patients and 100 matched controls were genotyped using PARP1 single nucleotide peptides (SNP's) rs1136410 and rs3219090 using TaqMan assays.RESULTS: The results indicated significantly higher risk with PARP1 rs1136410 minor allele "C" (OR=1.909; p=0.02942; CI, 1.060- 3.439). SNP rs1136410 also showed significantly increased risk in patients with smoking habit at C/C genotype and at minor allele C.CONCLUSIONS: The PAPR-1 Ala762Val polymorphism may play a role in progression of OSCC. Larger studies with a greater number of samples are needed to verify these findings.
Mohamed A.A.,Prince Sattam Bin Abdulaziz University
Proceedings of 2016 11th International Conference on Computer Engineering and Systems, ICCES 2016 | Year: 2016
The exponential growth of the Internet produces a huge amount of documents online. Finding the desired documents from amongst these huge resources is a difficult task. This problem is known as 'Information Overloading'. Automatic Text Summarization techniques (ATS) try to solve this problem by extracting the essential sentences that cover most of the main issues in the document. So the user will spend less time and effort to identify the main ideas of the document. Research in this field in the Arabic language is relatively new compared with the available research in English. This paper presents a preliminary study that investigates the effectiveness of using Non negative Matrix Factorization (NMF) algorithm to summarize the Arabic documents. The researcher of the present study has built an Arabic corpus of 150 documents manually and conducted extensive experiments by using different sentences scoring algorithms and term weighting schemes. The performance of the proposed algorithm has been measured, and the extensive experiments have shown that the NMF algorithm yields promising results. © 2016 IEEE.
Shamim M.,Prince Sattam bin Abdulaziz University
Indian Journal of Surgery | Year: 2017
The aim of the study is to study the pattern of injuries from road traffic accidents presented at the emergency department of a rural teaching institution in Karachi. This descriptive case series was conducted prospectively in the Emergency Department of Fatima Hospital and Baqai Medical University from 1 January 2012 to 21 March 2013. There were 385 patients in the series. All of the patients with recent injuries from road traffic accidents were included. Cases with injuries more than 72 h old were excluded. The majority of patients had lower limb injuries 172 (44.7%), followed by head and neck injuries 107 (27.8%), multiple injuries 62 (16.1%), upper limb injuries 22 (5.7%), abdominoperineal injuries 19 (5%), and chest injuries 3 (0.8%). Majority (229, 59.5%) of patients were given first aid treatment and discharged, while 151 (39.3%) patients were either admitted or referred to better equipped hospitals. Three patients were brought dead, and two patients left against medical advice. The lower limb injuries were the commonest road traffic accidental injuries, followed by head and neck injuries, multiple injuries, upper limb injuries, abdominoperineal injuries, and chest injuries. © 2017 Association of Surgeons of India
Assidmi L.,Prince Sattam Bin Abdulaziz University
Proceedings - 2015 5th International Conference on e-Learning, ECONF 2015 | Year: 2015
Public polices are instituted to create desired results in various domains. Policies implemented in social systems tend to fail due to the complexity of human relationships, including feedback that affects social behavior. Due to this complexity, even a policy implemented as a solution to a problem has the potential to worsen the status quo. Education systems are important examples of this scenario. One method to counter policy resistance is evidence-based learning. However, complex systems, like social systems, hinder the learning process. Beliefs and behaviors shape our mental model of a situation. The lengthy chronological distance between implemented policies, their impact, and subsequent results inhibits our ability to predict and prepare for the effects of a given policy on a social system. In this paper, systems thinking is explored as a tool for breaking through the limitations of our mental models in order to generate policies and learn from delayed evidence. A simple case is presented to illustrate the possible benefits of systems thinking on academic institutions, an example of a complex social system. © 2015 IEEE.
Al Yahya R.S.,Prince Sattam bin Abdulaziz University
Lasers in Medical Science | Year: 2016
Primary cutaneous amyloidosis (PCA) is a condition characterized by tissue deposition of misfolded proteins. PCA can present in different forms, namely macular, lichen, and nodular amyloidosis. These lesions can be of cosmetic concern and are difficult to treat. Many therapeutic modalities have been suggested for the treatment of PCA, with variable efficacy, including topical and systemic medications, phototherapy, electrodessication, dermabrasion, cryosurgery, and lasers. Over the past decade, several studies have reported successful treatment of PCA with different types of lasers; however, a review of these studies has never been reported in the dermatologic literature. The aim of this study was to review the efficacy and safety of lasers in the treatment of PCA. A search of the National Library of Medicine’s PubMed Database was performed. Studies were considered for inclusion based on their relevance, and specific data were extracted from all included studies. Eleven studies, comprising 64 patients, were included in this review. Significant improvements were observed in macular and lichen amyloidosis patients treated with carbon dioxide laser in two studies, while a number of case series and case reports showed good results with other types of laser in the treatment of PCA. This review was limited by the lack of large double-blinded randomized controlled trials and the overall small sample size. Laser treatment is a promising option in the treatment of PCA. Future randomized controlled trials are needed to compare the efficacy of different types of lasers and to select the best parameters for different types of PCA. © 2016, Springer-Verlag London.
Assidmi L.M.,Prince Sattam Bin Abdulaziz University
Proceedings of 2016 SAI Computing Conference, SAI 2016 | Year: 2016
The pursuit of national and international accreditation is critical for the recognition and ranking of newly established Saudi universities. However, the accreditation process requires extensive documentation of educational and administrative activities, which requires careful coordination and planning for timely collection, analysis, and reporting. Unfortunately, university-based eternal quality improvement programs are rarely amenable to those requirements and their associated timelines. This paper proposes Lean Six Sigma methodology as a tool to identify and address waste in the process of producing the necessary documents for accreditation. © 2016 IEEE.
Ashrafi S.A.,Prince Sattam Bin Abdulaziz University
International Journal of Applied Linguistics and English Literature | Year: 2016
The paper Human connection in Red badge of Courage sought to reestablish the notion that humanity survives the ravages of war, the war that kills and alienates a good chunk of human populace. The sounds of bullets cannot soften the tissues of heart, rather it only appalls humanity. Crane’s human connection is stressed as the succor for the tormented and oppressed nations mainly through wars. © 2016, Australian International Academic Centre PTY LTD. All rights reserved.
Al-Tamimi A.-M.S.,Prince Sattam Bin Abdulaziz University
Journal of Molecular Structure | Year: 2016
Density functional theory has been implemented to study the electronic structure, molecular properties and vibrational spectra of 3-(adamantan-1-yl)-4-(4-chlorophenyl)-1H-1,2,4-triazole-5(4H)-thione, a novel 1,2,4-triazole-5(4H)-thione derivative. Hydrogen bonded dimer of the title molecule has been studied using B3LYP, M06-2X and X3LYP functionals at 6-311++ G(d,p) level of theory. The intermolecular hydrogen bonding has been studied using NBO analysis of the dimer. Bader's AIM theory was also used to evaluate the strength as well as the hydrogen bonding characteristics. Experimental FT-IR and FT-Raman spectra of the title molecule were related with the spectral data obtained with DFT/B3LYP method. The 1H NMR chemical shifts of the title molecule were calculated by the GIAO method and compared with experimental results. Dipole moment, polarizability (α), first order static hyperpolarizability (β) along with molecular electrostatic potential surface have been calculated. Frequency-dependent first hyperpolarizabilities, β(-2ω;ω,ω) and β(-ω;ω,0) have also been evaluated to study the non-linear optical behavior of the title compound. UV-Vis spectrum of the title molecule was recorded and TD-DFT method has been used to calculate six lowest excited states and the corresponding excitation energies. © 2016 Elsevier B.V. All rights reserved.
Nusir M.,Prince Sattam Bin Abdulaziz University
Proceedings of 2016 International Conference on Information Management, ICIM 2016 | Year: 2016
Because of the increasing number of the postgraduate students in the universities, it usually takes quite a long time to fill the postgraduate project applications and to process these applications after being submitted. Therefore, developing a system that helps students and staff face these obstacles and saves time and efforts is being a must. This paper aims to develop a prototype system for postgraduate students in the University of Utara Malaysia (UUM), especially students in the Graduate Department of Information Technology and Computer Science, focusing on the entry requirements for the final project. The system development life cycle (SDLC) methodology will be used in this study as it is considered one of the best methodologies for system development. © 2016 IEEE.
University Of Bisha and Prince Sattam Bin Abdulaziz University | Date: 2016-09-13
The present disclosure describes a process for using saline water, and saline reject water produced in water purification, to use for gold mining production, and growing and harvesting algae. The disclosure also describes a method for growing and harvesting algae utilizing saline water as growth medium for recycling waste water to extract the remaining metals out of waste water. The harvested algae may be used in various applications including but not limited to water purification for gold mining production and to extract metals out of remaining waste water.