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Sant Feliu de Llobregat, Spain

Formiga F.,Hospital Universitari Of Bellvitge | Ferrer A.,Primary Health Care Center El Pla I | Camafort M.,Servicio de Medicina Interna | Sobrino J.,The Hypertension Unit | And 2 more authors.
Hipertension y Riesgo Vascular | Year: 2010

Objective: To study the influence of the circadian patterns of blood pressure and other factors related to geriatric evaluation in mortality of a nonagenarian cohort after a 3-year follow-up. Patients and methods: A total of 43 persons who formed a part of a Nona Santfeliu cohort were studied prospectively. A 24-hour ambulatory blood pressure monitoring (ABPM) study was performed. Sociodemographic, global geriatric evaluation and comorbidity data were collected. The nonagenarian subjects were followed-up for at least 36 months or until death. Results: The study was formed by 26 women (62%) and 16 men, with a mean of 93.7±2 years at the onset of the study. Twenty patients died during the three years of follow-up (47.6% mortality rate). There were no significant differences regarding mortality between the different 24-hour ABPM BP circadian patterns (p=0.16). The only statistically significant difference presented by the patients who died regarding those surviving at three years was that they the score had been worse on the cognitive mini-exam of Lobo. Conclusions: No statistically significant differences were found regarding mortality between the different circadian patterns of blood pressure of nonagenarian patients. The study shows that having a higher score on the cognitive evaluation is the best mortality predictor after three years of follow-up, regardless of the circadian pattern of ABPM of the BP. © 2009 SEHLELHA. Source


Ferrer A.,Primary Health Care Center El Pla I | Formiga F.,Hospital Universitari Of Bellvitge | Formiga F.,Bellvitge Biomedical Research Institute | Plana-Ripoll O.,Idiap Research Institute | And 4 more authors.
Archives of Gerontology and Geriatrics | Year: 2012

Falls are a source of morbidity and mortality in the oldest old. The purpose of this study was to describe the prevalence of falls among community-dwelling 85-year-olds and to study the factors associated with falling. A cross-sectional study, including geriatric assessment, was conducted within the framework of the Octabaix Study. Functional status was measured with Barthel Index (BI) and Lawton Index (LI), cognitive impairment was assessed with the Mini-Mental State Examination (MMSE), the Spanish version of which is called MEC, Comorbidity by Charlson Index (CCI), and data were gathered on nutritional risk, social risk, falls, and drugs. The fall prevalence among the 328 octogenarians studied was 28.4%. A bivariate analysis revealed an association with being female (p= 0.017) and poorer functional status according to BI (p= 0.027). Logistic analysis showed an association with female gender (OR = 1.96; 95%CI = 1.15-3.33; p= 0.014), BI (OR = 0.98; 95%CI = 0.97-0.99; p= 0.007) and MEC (OR = 1.05; 95%CI = 1.01-1.09; p= 0.027). The prevalence of falls among 85-year-olds is high and similar to that described in those aged 65 or over. The analyses show that being female, a degree of disability and a good score on cognitive status were independent risk factors for falls among these community-dwelling. © 2011 Elsevier Ireland Ltd. Source


Formiga F.,Hospital Universitari Of Bellvitge | Ferrer A.,Primary Health Care Center El Pla I | Rodriguez Molinero A.,Geriatric Unit | Fraga A.,Hospital Universitari Of Bellvitge | And 2 more authors.
Journal of Nutrition, Health and Aging | Year: 2011

Objectives: To evaluate vital status after five years of follow-up in a cohort of nonagenarians with functional and/or cognitive impairment at baseline. Design: Prospective cohort study. Setting: A community-based study. Participants: Nonagenarians enrolled in the NonaSantfeliu study. Measurements: Functional status was determined by the Lawton-Brody and Barthel indexes (BI), while cognition was assessed using the Spanish version of the Mini-Mental State Examination (MEC). Nonagenarians scoring up to 59 points on the BI were defined as individuals with significant functional impairment. Nonagenarians with cognitive decline were defined as those individuals with a score of 23 or less on the MEC. Subjects scoring <60 on the BI and <24 on the MEC were considered to show combined impairment (both functional and cognitive). Results: Sixty-three of 71 (88.8%) subjects with a BI <60 and 73 of 84 (86.9%) with a MEC score <24 had died after five years. Forty-eight of 53 nonagenarians (90%) with combined impairment died during the same follow-up period. A prior diagnosis of heart failure was the only variable associated with higher mortality in the three groups of subjects. Conclusion: Most of the nonagenarian subjects with functional and/or cognitive impairment at baseline had died at five-year follow-up © 2011 Serdi and Springer Verlag France. Source


Formiga F.,Hospital Universitari Of Bellvitge | Ferrer A.,Primary Health Care Center El Pla I | Padros G.,Laboratori Clinic Metropolitana Sud | Soto A.L.,Geriatric Unit | And 2 more authors.
Aging Clinical and Experimental Research | Year: 2011

Background and aims: The presence of an immune-risk phenotype (IRP) has been correlated with survival rates in elderly people. The aim of this study is to characterize the inverted CD4:CD8 ratio as a possible marker of IRP in a sample of oldest old (85 years) by assessing differences in gender and health status. Methods: Comorbidity, functional status (Barthel Index), and cognitive status with the Spanish version of the Mini-Mental State Examination were evaluated. Non-disabled subjects were defined as those with better health status, with scores of >90 on the Barthel Index and >23 points on the Spanish version of the Mini-Mental State Examination. CD4:CD8 ratios were recorded, and a ratio of 1.00 or less was used to define IRF. Results: Three hundred and twelve subjects aged 85 years old were studied, 190 women (60.9%) and 122 men. The CD4:CD8 ratio was 1.00 or less in 47 subjects (15.6%) and higher than 2.2 in 115 (36.8%). There were no differences in CD4:CD8 ratio according to health status. The inverted CD4:CD8 ratio was more frequent in men (55.3%). Conclusion: In this community-dwelling, single year birth cohort study, the subgroup with poor health status did not have a lower CD4:CD8 ratio. The inverted CD4:CD8 ratio was more frequent in men. ©2011, Editrice Kurtis. Source


Formiga F.,Hospital Universitari Of Bellvitge | Ferrer A.,Primary Health Care Center El Pla I | Montero A.,Hospital Universitari Of Bellvitge | Chivite D.,Hospital Universitari Of Bellvitge | Pujol R.,Hospital Universitari Of Bellvitge
Journal of Nutrition, Health and Aging | Year: 2010

Objectives: To examine the survival rates of subjects aged 95 or over after a follow-up period of 3 years, and to determine predictive factors for mortality risk. Design: A prospective cohort study. Setting: A community-based study. Participants: Forty-eight subjects aged 95 or over. Measurements: Sociodemographic data, Barthel Index, Lawton-Brody Index, Spanish version of the Mini-Mental State Examination, short version of the Mini Nutritional Assessment, comorbidity (Charlson Index), and prevalent chronic diseases were evaluated. Patients who died were compared with the rest. Results: Thirty-six deaths (75%) were recorded during follow-up. The Cox multivariate analysis showed that lower Barthel Index scores and a history of heart failure were independently associated with long-term mortality. Conclusions: In subjects aged 95 or over, poor functional status and history of heart failure were the two independent risk factors for 3-year mortality. The Journal of Nutrition, Health and Aging©. Source

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