Entity

Time filter

Source Type

Doñinos de Salamanca, Spain

Chamoso P.,University of Salamanca | Garcia-Ortiz L.,Primary care Research unit La Alamedilla | Recio-Rodriguez J.I.,Primary care Research unit La Alamedilla | Gomez-Marcos M.A.,Primary care Research unit La Alamedilla
Advances in Intelligent Systems and Computing | Year: 2014

Recent studies have found retinal vessel caliber to be related to the risk of hypertension, left ventricular hypertrophy, metabolic syndrome, stroke and others coronary artery diseases. The vascular system in the human retina is easily perceived in its natural living state by the use of a retinal camera. Nowadays, there is general experimental agreement on the analysis of the patterns of the retinal blood vessels in the normal human retina. The development of automated tools designed to improve performance and decrease interobserver variability, therefore, appears necessary. This paper presents a study focused on developing a technological platform specialized in assessing retinal vessel caliber and describing the relationship of the results obtained to cardiovascular risk. © Springer International Publishing Switzerland 2014. Source


Verde G.,University of Salamanca | Garcia-Ortiz L.,Primary care Research unit La Alamedilla | Rodriguez S.,University of Salamanca | Recio-Rodriguez J.I.,Primary care Research unit La Alamedilla | And 4 more authors.
Advances in Intelligent Systems and Computing | Year: 2013

The scope of this work is to develop a technological platform specialized in assessing retinal vessel caliber and describing the relationship of the results obtained to cardiovascular risk. Population studies conducted have found retinal vessel caliber to be related to the risk of hypertension, left ventricular hypertrophy, metabolic syndrome, stroke, and coronary artery disease. The vascular system in the human retina has a unique property: it is easily observed in its natural living state in the human retina by the use of a retinal camera. Retinal circulation is an area of active research by numerous groups, and there is general experimental agreement on the analysis of the patterns of the retinal blood vessels in the normal human retina. The development of automated tools designed to improve performance and decrease interobserver variability, therefore, appears necessary. © Springer International Publishing Switzerland 2013. Source


Garcia-Ortiz L.,Primary care Research unit La Alamedilla | Recio-Rodriguez J.I.,Primary care Research unit La Alamedilla | Parra-Sanchez J.,Primary care Research unit La Alamedilla | Elena L.J.G.,Primary care Research unit La Alamedilla | And 4 more authors.
Journal of Hypertension | Year: 2012

Objective: To analyze the reliability and validity of a semiautomated tool for assessing retinal vessel caliber and to describe the relationship of measures taken to cardiovascular risk and target organ damage. Methods: A total of 210 patients aged 34-75 years were selected with retinography. Retinal photographs were digitized, and superior and inferior temporal vessels were measured in an area 0.5-1 disk diameter from the optic disc with semiautomated software [arteriole/venule index (AVIx) calculator]. AVIx was also estimated. Vascular damage was assessed using carotid intima-media thickness and pulse wave velocity, cardiac damage using Cornell voltage-duration product, renal damage using the glomerular filtration rate and microalbuminuria, and cardiovascular risk with the Framingham score. Results: Interobserver intraclass correlation coefficient (ICC) ranged from 0.96 [95% confidence interval (CI) 0.94-0.97] to 0.99 (95% CI 0.98-0.99), and intraobserver ICC ranged from 0.97 (95% CI 0.94-0.98) to 0.99 (95% CI 0.99-0.99). In the Bland-Altman plot, the limit of interobserver agreement was-0.009 (0.066 to-0.086) in right AVIx and-0.001 (0.083 to-0.085) in left AVIx, whereas the limit of intraobserver agreement for overall AVIx was-0.005 (-0.057 to-0.047). Cardiovascular risk and albumin-creatinine ratio were higher in the first tertile of AVIx as compared with the other two (P < 0.05). In multiple regression, AVIx and venule caliber, but not artery caliber, behaved as predictors of cardiovascular risk and microalbuminuria. Conclusion: This tool showed a high intraobserver and interobserver reliability, and results of the validity analysis agree with those from large studies in estimation of cardiovascular risk and evaluation of target organ damage. © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins. Source

Discover hidden collaborations