Pontifical Catholic University of Campinas

Dom Pedro, Brazil

The Pontifícia Universidade Católica de Campinas is a private and non-profit Catholic university, located in Campinas, the second largest city of the State of São Paulo. It is maintained by the Catholic Archdiocese of Campinas.Founded in June 1941, with the first college teaching Philosophy, Science and Letters, it became a full university in 1955. The title of Pontifical University was granted by Pope Paul VI in 1972. The university has three campuses in the city.The university has approximately 20,000 students enrolled in undergraduate and graduate courses. Undergraduate classes are in administration, system analysis, architecture, arts, accounting, biology, medicine, information science and library science, economics, theology, pharmacy, law, social science, literature, physical education, nursing, dentistry, physical therapy, speech therapy, nutrition science, engineering , philosophy, geography, journalism, history, pedagogy, psychology, publicity, public relations, chemistry, social services, occupational therapy and tourism.The Central Campus is the main building, and the Building of Arts. The university was founded in the central building in 1941. Campus I is the largest space in PUC-Campinas, where more than 50% of students at the university study and where the Rectory is located. The land of campus I was donated by sisters Vera and Ana Beatriz, daughter of agronomist Caio Guimarães Pinto, former owner of the Santa Candida Farm. Guimaraes had a dream to build a university. The construction of the buildings began when the land was donated in 1970. Three years later, the Institute of Arts, Communications and Tourism and the School of Physical Education became operational. The campus was opened in 1976.The schools are Centre for Economics and Business Administration , Centre for Mathematical science, Environmental and Technology , Centre for Applied Social and Human science , except Law, and Centre for Language and Communication .Campus II is named "Centro de Ciências da Vida" and it is known as the "Health City." It has this name because all of the university's courses are gathered there. The CCV's courses comprise the following colleges: Biologic science, Pharmacy, Nursing, Physiotherapy, Speech Therapy, Medicine, Nutrition, Dentistry, Psychology and Occupational Therapy. The CCV has 33 laboratories, pharmacy school, outpatient services of physiotherapy and occupational therapy, speech therapy clinics, dental and physiotherapy services.On the same campus is also located the Celso Pierro Hospital and Maternity , which has 350 beds and 35 medical specialties. Every year, 450 thousand patients are treated by the Unified Health System . In Brazil, PUC-Campinas and University of São Paulo are the best in Health.The Celso Pierro Hospital has 340 beds, 240 for the covenant of the Unified Health System and 100 for HMOs and private individuals distributed in inpatient units, emergency rooms adult, child, gynecology/obstetrics and orthopedics, and Intensive Care Units adult, pediatric and neonatal coronary. Wikipedia.

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Ribak S.,Pontifical Catholic University of Campinas
Techniques in Hand and Upper Extremity Surgery | Year: 2017

Patients with hand muscular atrophy due to damage of the ulnar nerve could be stigmatized for their appearance. Unsatisfactory results in the attempt to correct the atrophy are reported in the literature. Fat grafting is an autologous and easily obtainable graft, antigenic response is very unlikely, it does not require any special material, and the procedure has a low cost. The technique of autologous fat grafting by using fat block, to remodel the first interdigital space, is useful and safe in correcting muscle atrophy of the first interdigital space caused by the injury of the ulnar nerve. This technique is suitable for muscular atrophy caused by injury of the ulnar nerve and nerve compression as well as patients present with esthetic complaints. Fifteen cases were operated using this technique. After the surgery, the resorption of the graft ranged between 12.5% and 66.7%, averaging 28%. Patients were able to check the benefit provided by filling of the atrophied area, which allowed a serene return to their daily life activities, living with others, reducing the need to hide their hands, and even facilitating their reintegration into the labor market. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved

Objective: To assess whether changes in dietary intake and physical activity pattern are associated with the annual body mass index (BMI) z-score change among adolescents. Methods: The study was conducted in public schools in the city of Piracicaba, Sao Paulo, Brazil, with a probabilistic sample of 431 adolescents participating in wave I (2004) (hereafter, baseline) and 299 in wave II (2005) (hereafter, follow-up). BMI, usual food intake, physical activity, screen time, sexual maturation and demographic variables were assessed twice. The association between annual change in food intake, physical activity, screen time, and annual BMI z-score changes were assessed by multiple regression. Results: The study showed a positive variation in BMI z-score over one- -year. Among variables related to physical activity pattern only playing videogame and using computer increased over the year. The intake of fruits and vegetables and sugar-sweetened beverages increased over one year, while the others variables showed a reduction. An increased consumption of fatty foods (β = 0.04, p = 0.04) and sweetened natural fruit juices (β = 0.05, p = 0.03) was positively associated with the rise in BMI z-score. Conclusions: Unhealthy dietary habits can predict the BMI z-score gain more than the physical activity pattern. The intake of fatty foods and sweetened fruit juices is associated with the BMI z-score over one year.

Gomes P.H.,University of Southern California | Da Fonseca N.L.S.,University of Campinas | Branquinho O.C.,Pontifical Catholic University of Campinas
IEEE Transactions on Mobile Computing | Year: 2014

This paper proposes an architecture for mobile wireless networks based on Radio-over-Fiber (RoF) technology. The architecture organizes cells in a multi-tier fashion, with different tiers covering areas with different radii lengths. Proposed optimization algorithm splits cells to improve network capacity in congested areas and merges cells when the demand is low. The evaluation of the effectiveness of the proposed model considered three distinct objectives: minimization of the number of base stations used, maximization of the number of users served, and minimization of network energy consumption. The combination of the first two objectives was also evaluated. Three algorithms based on linear relaxation techniques are introduced for rapid computation of the near-optimum solutions. The proposed architecture is shown to lead to network infrastructures that save costs and energy and yet provide service to a large number of users. © 2002-2012 IEEE.

Harrison J.,Loughborough University | Beraquet V.,Pontifical Catholic University of Campinas
Health Information and Libraries Journal | Year: 2010

Aims: The aims of this research were to determine the background, education, training experience, roles and responsibilities of practising Clinical Librarians (CL) in the UK. This paper reports the findings of a survey undertaken in 2007 at the third Clinical Librarian conference. This research builds on research undertaken by Harrison and Sargeant in 2002 and Ward in 2004, and can be considered as part of a longitudinal study of the role of the CL in the UK. Objectives: The objectives of the research were to define and gain a broad understanding of the role of the CL in the UK highlighting similarities and differences amongst the professionals and provide evidence for a baseline of skills and activities for the CL role. The type of sampling used was Judgemental. Results/analysis: Results/analysis detail the skills and activities undertaken by CLs. Searching for information for Clinicians was the activity most frequently undertaken. Developing good relationships with other healthcare professionals was considered essential. Two-thirds of the respondents held a postgraduate library qualification. Conclusions: Crucially a new model for the UK CL role is derived drawing on the findings of this study and the existing literature. © 2009 Health Libraries Group.

Pott Junior H.,Pontifical Catholic University of Campinas
Revista brasileira de reumatologia | Year: 2012

Serositis is commonly seen in systemic lupus erythematosus (SLE). Approximately 16% of patients with SLE have pleural or pericardial involvement. However, peritoneal involvement is extremely rare, and clinically seen in a small group of patients. This is the case report of a 47-year old female with discoid lupus who evolved with systemic manifestations of the disease, characterized by significant abdominal distension and pain, asthenia, weight loss, signs of ascites, and acute non-invasive diarrhea. Exhaustive diagnostic investigation was performed and included laboratory and imaging tests, colonoscopy, and analysis of the ascitic fluid. Besides ruling out the possibility of an infectious, neoplastic, and hemodynamic etiology, the investigation also allowed the confirmation of SLE. Thus, the hypothesis of lupus peritonitis with ascites became viable. The patient was treated with prednisone and chloroquine, with substantial improvement of her condition.

Villagelin D.G.,Pontifical Catholic University of Campinas
Journal of endocrinological investigation | Year: 2011

Papillary thyroid carcinoma (PTC) is the most frequently diagnosed endocrine neoplasia, representing 70 to 80% of all diagnosed thyroid cancers. Furthermore, Hashimoto's thyroiditis is a frequent inflammatory thyroid disease and the main cause of hypothyroidism. The relationship between Hashimoto's thyroiditis and PTC remains controversial. Surgery for PTC was performed at our institution on 157 consecutive patients. They were classified by the degree of lymphocyte infiltration (LI). LI was classified as diffuse LI or peritumoral LI (only in or around the tumor), or absent. In addition, age, gender, tumor size, histopathological findings, lymph-node metastasis, extra- thyroidal extension, multifocal tumor, coexistence of LI and clinical outcomes were analyzed. Out of the 141 patients included in the study, 83 (59%) had diffuse LI and 22 (16%) had peritumoral LI. In 36 patients (25%) LI was absent. A comparison of patients in the 3 groups revealed no significant difference in their genders, ages, smoking status, thyroid function, or nodule size at the time of surgery. The characteristics of PTC showed no differences in lymph-node metastasis, tumor invasion into contiguous neck structures, angioinvasion, or PTC subtypes. Tumor-node-metastasis (TNM) classification and classes did not differ among the 3 groups. During the follow-up, 64 out of 141 patients with PTC (55%) had recurrences from 6 to 130 months after the initial treatment. After a mean follow-up period of 8 yr we observed a significantly (p=0.01) high recurrence (66.6%) in the LI absent group with 24 of 36 patients when compared to patients from the diffuse LI group (32 out of 83 patients; 38.5%) and peritumoral LI group (8 out of 22 patients; 25%). Although the role of the inflammatory-immune cells is complex and little understood, we found a more favorable course of PTC in the presence of LI (diffuse or peritumoral); this supports the hypothesis that LI represents a form of immune reaction to control tumor growth and proliferation.

Fonseca L.C.,Pontifical Catholic University of Campinas
Arquivos de neuro-psiquiatria | Year: 2011

To evaluate the relationship between specific cognitive aspects and quantitative EEG measures, in patients with mild or moderate Alzheimer's disease (AD). Thirty-eight AD patients and 31 controls were assessed by CERAD neuropsychological battery (Consortium to Establish a Registry for AD) and the electroencephalogram (EEG). The absolute power and coherences EEG measures were calculated at rest. The correlations between the cognitive variables and the EEG were evaluated. In the AD group there were significant correlations between different coherence EEG measures and Mini-Mental State Examination, verbal fluency, modified Boston naming, word list memory with repetition, word list recall and recognition, and constructional praxis (p<0.01). These correlations were all negative for the delta and theta bands and positive for alpha and beta. There were no correlations between cognitive aspects and absolute EEG power. The coherence EEG measures reflect different forms in the relationship between regions related to various cognitive dysfunctions.

Reis L.O.,University of Campinas | Reis L.O.,Pontifical Catholic University of Campinas
Endocrine-Related Cancer | Year: 2012

The hypothesis 'the lower the better when achieving castration levels of testosterone' is based on the data from second-line hormonal manipulation and its molecular basis, and on better oncological results reported for lower castration levels in prostate cancer (PCa) patients, including those achieved with maximal androgen blockade. In this regard, the equivalence of surgical and different pharmacological castrations has been controversial. The modified amino acid structure that makes LH-releasing hormone (LHRH) analogs more potent than LHRH, and the method of delivering the analogs impacts on bioavailibility and potentially causes differences in androgen levels and in its final oncological efficacy. In addition to this, there is a myriad of circumstances, such as those related to ethnic variations and co-morbidities, which uniquely impact on the pharmacological approach in a highly heterogeneous population of castration-resistant prostate cancer (CRPC) patients. Ineffective testosterone suppression through hormonal escape is currently poorly recognized and may result in increased PCa mortality. Until now, the optimal serum testosterone level in patients under castration, and the impact of its variations in patients under LHRH therapy, remain open questions and have been merged to a broad spectra of patients who are highly heterogeneous. This heterogeneity relates to a number of mechanisms regarding response to treatment, which influences the biology of the relapsing tumor and the sensitivity to subsequent therapies in the individual patient. The rationale to achieve testosterone levels below 20-50 ng/dl warrant further investigation as these levels have recently rescued CRPC patients. In the last few years and months, important advancements in prostate cancer treatment have been achieved. Nevertheless, these advances are measured in a few months of additional survival and under high costs, not available to most of the world population, compared with the benefits of hormonal manipulation that are measured in years, there is a huge potential for accessible and durable effect expansion and optimization of treatment, particularly with the current tendency of a more individual approach. © 2012 Society for Endocrinology.

Leandro-Merhi V.A.,Pontifical Catholic University of Campinas | De Aquino J.L.B.,Pontifical Catholic University of Campinas | De Camargo J.G.T.,Pontifical Catholic University of Campinas
Journal of Nutrition, Health and Aging | Year: 2012

Objectives: This study aimed to assess the agreement between body mass index, calf circumference, arm circumference, habitual energy intake and the mini nutritional assessment (MNA) and then assess the accuracy of these parameters in relation to the MNA. Method: The nutritional status of 132 hospitalized elderly was assessed with the MNA, body mass index (BMI), calf circumference (CC) and arm circumference (AC). Their habitual energy intake (HEI) was also determined. The chi-square and the Mann-Whitney tests were used. The agreement between the nutritional risk criteria and the MNA was determined by the Kappa coefficient. The ROC curve was used to determine the accuracy of the parameters in relation to the MNA and to determine the cut-off values. The significance level was set at 5% (p<0.05). Results: A little more than half the sample (54.5%) was well nourished, 34.9% were at risk of malnutrition and 10.6% were malnourished. There was good agreement only for BMI<22 (Kappa=0.44), with an accuracy (AUC) of 0.78. no agreement was found for the other parameters, their sensitivities were shown to be low. However, CC and AC were very specific for determining the well nourished patients: The CC specificity was 86.1% and AC specificity was 94.4%. The cutoff values determined by the ROC curve were ≤23.2 for BMI, ≤26.2 for AC and ≤32.2 for CC. Conclusion: The best parameters to determine nutritional risk in relation to the MNA were AC, BMI and CC. However, these nutritional assessment parameters should be used to replace the MNA for the assessment of hospitalized elderly patients with their current cut-off points.

Leandro-Merhi V.A.,Pontifical Catholic University of Campinas | Braga de Aquino J.L.,Pontifical Catholic University of Campinas
Clinical Nutrition | Year: 2015

Background & aims: Nowadays studies are advised to compare nutritional risk assessed by different instruments with clinical outcomes. This study compared nutritional diagnosis methods and identified the best predictor of clinical outcomes. Methods: This cross-sectional study included 500 hospitalized patients with neoplasms and digestive tract diseases (DTD). Their nutritional status was determined by nutritional risk screening (NRS), subjective global assessment (SGA), and anthropometry, and compared with the clinical outcomes. The Kappa coefficient measured the agreement between the methods. Associations between risk factors and clinical outcomes were investigated by Cox, univariate logistic, and multiple logistic regression analyses at a significance level of 5%. Results: In DTD and cancer patients, SGA and NRS presented good agreement, but agreement of either with anthropometry was poor. According to Cox regression, both SGA and NRS predicted complications in DTD patients. However, none of the instruments was capable of predicting complications in cancer patients or death in DTD patients. In cancer patients, SGA and age were considered risk factors for death. In DTD patients, age, SGA, and NRS predicted a long hospital stay. In cancer patients, long stays were associated with age and SGA. Conclusion: SGA and NRS are highly sensitive for predicting complications in DTD patients. Old age and SGA predicted death in cancer patients. Advanced age and SGA also predicted long hospital stays for DTD and cancer patients, but NRS predicted long hospital stays only for DTD patients. © 2014 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism.

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