Pondicherry Institute of Medical SciencesPondicherry

Puducherry, India

Pondicherry Institute of Medical SciencesPondicherry

Puducherry, India
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Jose A.,Pondicherry Institute of Medical SciencesPondicherry | Suranigi S.M.,Pondicherry Institute of Medical SciencesPondicherry | Deniese P.N.,Pondicherry Institute of Medical SciencesPondicherry | Babu A.T.,Pondicherry Institute of Medical SciencesPondicherry | And 2 more authors.
Journal of Clinical and Diagnostic Research | Year: 2017

Introduction: Fracture of the distal end of radius represents the most common fracture of the upper extremity accounting for approximately 16-20% of all fractures. Plating is now emerging as the gold standard for management of distal radius fractures due to increased rate of complications such as malunion, subluxation/dislocation of distal radio-ulnar joint or late collapse of fracture. Procedures such as closed reduction and cast immobilization, ligamentotaxis with external fixator and percutaneous pin fixation are no longer acceptable. Aim: The purpose of the study was to evaluate the functional and radiological outcome of unstable distal radius fractures treated with the volar locking plate. Materials and Methods: We reviewed 53 patients from January 2011 to December 2015, treated for unstable distal radius fractures using a volar locking compression plate. Standard radiographic and clinical assessment after 12 months (range 12-16 months) were measured and final functional and radiological outcome were assessed using the Modified Mayo wrist scoring system and Sarmiento’s modification of Lindstorm criteria respectively.Results: There were 42 males and 11 females with an average age of 39.12±31.78 years (18-71 years). At the end of 12 months, 36 patients had an excellent radiological outcome and 10 patients had good radiological outcome as per Sarmiento’s modification of Lindstorm criteria. Eleven patients had an excellent functional outcome and 26 patients had a good functional outcome as per modified Mayo wrist scoring system. There was one case of superficial wound infection which subsided with intravenous antibiotics. Conclusion: The volar locking plate fixation helps in early mobilization of the wrist, restores anatomy, allows early return to function, prevents secondary loss of reduction and hence is an effective treatment for unstable fractures of the distal radius. © 2017, Journal of Clinical and Diagnostic Research. All rights reserved.


Natarajan V.,Pondicherry Institute of Medical SciencesPondicherry | John K.,Pondicherry Institute of Medical SciencesPondicherry | Jose D.,Pondicherry Institute of Medical SciencesPondicherry | Kalaiselvan P.,Pondicherry Institute of Medical SciencesPondicherry | Das A.K.,Pondicherry Institute of Medical SciencesPondicherry
Journal of Clinical and Diagnostic Research | Year: 2017

Vascular thrombosis is one of the complications of tuberculosis. Deep vein thrombosis and pulmonary thrombosis have been reported with pulmonary and extrapulmonary tuberculosis. Splenic involvement in abdominal tuberculosis is among the rarest manifestations. Disseminated tuberculosis is predominantly reported in rheumatoid arthritis following ingestion of biological agents. Here, we report a case of disseminated tuberculosis in a rheumatoid arthritis patient who was on steroids and methotrexate for a long period, presenting with multiple splenic lesion and portal vein thrombosis, which was not reported earlier. She was treated with antitubercular drugs, anticoagulants and showed improvement. © 2017, Journal of Clinical and Diagnostic Research. All rights reserved.


Vargis R.S.,Pondicherry Institute of Medical SciencesPondicherry | Phansalkar M.,Pondicherry Institute of Medical SciencesPondicherry | Padhi S.,Pondicherry Institute of Medical SciencesPondicherry | Phansalkar D.,Pondicherry Institute of Medical SciencesPondicherry | Nair S.R.,Pondicherry Institute of Medical SciencesPondicherry
Journal of Clinical and Diagnostic Research | Year: 2017

Overall incidence of primary cardiac tumours ranges from 0.0017% and 0.27% at autopsy. Cardiac haemangiomas are rare, and account for 2.8% of benign cardiac tumours. Pericardial haemangiomas, in particular are extremely rare. Pericardial haemangiomas are reported to present with a variety of symptoms such as dyspnea, palpitation, atypical chest pain. Other symptoms like obstruction of blood vessels, cardiac tamponade, or pericardial effusion may result due to compression of surrounding structures. Here we report a case of pericardial haemangioma in a patient who presented with breathlessness and cough. © 2017, Journal of Clinical and Diagnostic Research. All rights reserved.


Tahmina S.,Pondicherry Institute of Medical SciencesPondicherry | Daniel M.,Pondicherry Institute of Medical SciencesPondicherry
Journal of the ASEAN Federation of Endocrine Societies | Year: 2017

Objective. To compare the maternal and perinatal outcomes in women with GDM diagnosed by Carpenter & Coustan (CC) criteria and by the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria. Methodology. A cross-sectional comparative study was conducted using data of women who were screened and diagnosed with GDM between April 2006-March 2007 using the CC criteria and April 2013-March 2014 using IADPSG criteria. Maternal and perinatal outcomes were noted. Means and proportions were calculated for continuous and categorical variables respectively. Data were analyzed using t-test for normally distributed data and Mann-Whitney U test for those that were not normally distributed. Pearson Chi-square test was used to find an association between the various outcomes between the two groups. Results. Among 500 pregnant women screened, 36 were diagnosed GDM in the CC group. In the IADPSG group, 733 women were screened and 167 were diagnosed GDM. Prevalence of GDM was 7.2% in CC group and 22.78% in IADPSG group (p=0.000). There was a statistically significant difference in the number of women who developed hypertension and polyhydramnios among the two groups. Women who had an operative vaginal delivery (16.67% vs. 6.6%, p=0.085) and mean birth weight (3.10 ± 0.55 kg vs. 2.97 ± 0.48 kg, p=0.165) were higher in CC group than the IADPSG group. Among the perinatal outcomes, a statistically significant improvement was found in the number of neonates developing respiratory distress syndrome (p=0.000) and hyperbilirubinemia (p=0.000), when the IADPSG criteria were used. Conclusions. There is a statistically significant difference between the maternal and neonatal outcomes when the newer IADPSG criteria were used for diagnosis of GDM. © 2017 by the JAFES.


Simiyon M.,Pondicherry Institute of medical sciencesPondicherry | Chandra P.S.,National Institute of Mental Health and Neuro Sciences | Desai G.,National Institute of Mental Health and Neuro Sciences
Asian Journal of Psychiatry | Year: 2016

Sexual dysfunction among women usually has a multifactorial etiology and is also difficult to study in cultures where open discussions about sexuality are not common. Not much is known about sexual function in women with schizophrenia even though it may have a significant impact on their quality of life and maybe influenced by several factors. Aims and objectives This study aimed to assess the frequency and nature of sexual dysfunction in women with schizophrenia and study its association with marital quality, illness, treatment, and socio-demographic factors. Methodology This was a cross sectional, hospital-based study conducted among 63 women with schizophrenia attending the outpatient services of a tertiary care psychiatric hospital. Sexual dysfunction was assessed using the Female Sexual Function Index (FSFI). Side effects of medications, psychopathology, and marital quality were assessed using standard scales. Results Among the 63 women assessed, 44 (70%) reported sexual dysfunction. Impaired desire was reported by all women, impaired arousal by 58 (92.1%), poor lubrication by 30 (47.6%), impaired orgasm by 48(76.2%) poor satisfaction by 44(69.8%) and pain by 23(36.5%). Poor Marital quality (‘p’ value-0.001), higher scores on general psychopathology of the Positive and Negative symptoms scale of schizophrenia (PANSS) (‘p’ value-0.049) and side effects such as weight gain, menstrual disturbances, galactorrohea and dry vagina were significantly associated with Female Sexual Dysfunction (FSD) in univariate analysis. However, multivariate analysis found marital quality alone to be significantly related to FSD. © 2016 Elsevier B.V.


Praveenkumar U.,Institute of Medical SciencesPondicherry | Ganguly S.,Pondicherry Institute of Medical SciencesPondicherry | Ray L.,Pondicherry Institute of Medical SciencesPondicherry | Nanda S.K.,Pondicherry Institute of Medical SciencesPondicherry | Kuruvila S.,Pondicherry Institute of Medical SciencesPondicherry
Journal of Clinical and Diagnostic Research | Year: 2016

Introduction: Previous studies indicate a higher prevalence of metabolic syndrome in psoriatic patients. This study aimed to investigate the association of metabolic syndrome and its components with psoriasis. It also studied the relation between presence of metabolic syndrome and disease duration in psoriasis patients. Materials and Methods: This was a hospital-based, case-control study conducted with 30 clinically diagnosed patients of chronic plaque psoriasis and 30 age-and sex-matched control subjects. Height, weight, BMI, blood pressure and waist circumference were assessed in all the subjects. Fasting levels of serum glucose, serum triglycerides and serum HDL were estimated by automated clinical chemistry analyser. Metabolic syndrome was diagnosed by the presence of at least 3 criteria of NCEP ATP III with Asian modification for waist circumference. Results: Metabolic syndrome was more common in psoriatic patients than in controls but the difference was statistically insignificant (60% vs. 40%, p-value=0.12). The psoriasis group had a higher prevalence of elevated blood glucose levels and higher waist circumference compared to controls. Psoriasis patients had a higher prevalence of high triglyceride levels than controls, the difference being statistically insignificant (40% vs. 30%, p-value = 0.41). The prevalence of low HDL levels was significantly higher in cases compared to controls (86.7% vs. 60%, p-value = 0.02). There was no relation between presence of metabolic syndrome and duration of psoriasis. Conclusion: Our findings suggest that metabolic syndrome as well as dyslipidaemia is commoner in psoriasis patients. This underlines the need for screening of all psoriasis patients for early diagnosis and treatment of associated metabolic syndrome to reduce the high burden of morbidity and mortality. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved.


Priyadharshini G.,Pondicherry Institute of Medical SciencesPondicherry | Varghese R.G.,Pondicherry Institute of Medical SciencesPondicherry | Phansalkar M.,Pondicherry Institute of Medical SciencesPondicherry | Ramdas A.,Pondicherry Institute of Medical SciencesPondicherry | And 2 more authors.
Journal of Clinical and Diagnostic Research | Year: 2015

Background: Subcutaneous fungal infections are caused by penetration of the causative fungi into the subcutaneous layer and are usually localised. We present a series of eight cases with subcutaneous fungal cystic lesions masquerading as benign lesions. Materials and Methods: A retrospective study was conducted on subcutaneous fungal infections seen between January 2007 to July 2014 in the Department of Pathology. Eight patients with biopsy proven subcutaneous fungal infection were included. We collected and analysed their demographic, clinical and histopathological details. Results: Among eight patients, six were male and two were female. The mean age was 47 years (Range: 21-70). All the eight patients presented with non-tender cystic swelling. The size of the swellings varied from a minimum of 3x3 cm to maximum of 10x4 cm. Out of eight, hand was involved in three, forearm in one, elbow in two, leg in one and foot in one. On H&E staining, all the cases showed fibro collagenous cyst wall, lined by histiocytes, granulomatous reaction, foreign body type of giant cells with acute and chronic inflammatory infiltrate containing fungal elements. Six were identified as hyalohyphomycosis and two were identified as phaeohyphomycotic cysts based on pigmentation of hyphae. Conclusion: Fungal infection should be suspected in all subcutaneous cystic lesions. Excised tissue should always be sent for culture and histopathology. © 2015, Journal of Clinical and Diagnostic Research. All Rights Reserved.

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