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Bucharest, Romania

Bacalbasa N.,UMF Carol Davila | Blescu I.,Ponderas Hospital
Annals of Fundeni Hospital | Year: 2013

Ovarian cancer is one of the most agressive gynaecologic malignancies and the fifth most common cause of death in females worlwide. Most studies showed that a complete cytoreductive surgery with no macroscopic residual disease combined with chemotherapy (intraperitoneal and/or systemic) represent the best therapeutic option for these patients. However R0 resection cannot be achieved in all situations, due to vascular involvement or other particular situations. Based on the principle that cytoreduction brings survival benefit, one can wonder if an incomplete resection whenever an R0 resection is technically not feasible should be considered. We present a 58 years old patient diagnosed with well differentiated ovarian cystadenocarcinoma for which she underwent total hysterectomy with bilateral adnexectomy in 2009. She later underwent 6 cycles of adjuvant chemotherapy with platinum-taxanes combination. In 2011 she was diagnosed with a pelvic recurrence which was resected. She continued second line chemotherapy with gemcitabine.The patient was referred to us in September 2013 with a large pelvic recurrence with left iliac artery invasion and a colo-parietal fistula. The patient also presented 8 intraparenchimatous liver metastases. Since the patient was undergoing 4th line chemotherapy and proved nonresponding and also considering the colo-parietal fistula debulking R1 surgery was considered. © 2013, Versita. All rights reserved.

Bacalbasa N.,UMF Carol Davila | Balescu I.,Ponderas Hospital | Filipescu A.,UMF Carol Davila
Gineco.eu | Year: 2014

Ovarian cancer represents one of the most aggressive gynecologic malignancies, most women still being diagnosed in an advanced stage of the disease. Although primary maximal cytoreduction associated with adjuvant chemotherapy seems to be the most efficient way to achieve a good control of the disease most patients recurre at a certain moment. In these cases secondary and tertiary cytoreduction appear to be associated with a significant survival benefit. Studies regarding the role of cytoreduction beyond tertiary surgery remain scarce but preliminary reports proove that in selected cases this might represent a reasonable option in order to prolong survival.

Bacalbasa N.,Carol Davila University of Medicine and Pharmacy | Balescu I.,Ponderas Hospital
Gineco.eu | Year: 2015

Endometrial stromal sarcomas (ESS) are rare mesenchymal tumors of the uterus characterized by an indolent behavior and favorable outcomes. However, late recurrence is a common event even in cases diagnosed in an early stage of the disease. The present review presents the largest studies which focused on determining the prognostic factors and outcomes after surgically treated ESS. In this respect, we also presents various answers for the most significant unsolved questions regarding the role of bilateral adnexectomy and the benefits of pelvic and para-aortic lymph node dissection. © 2015 Romanian Society of Ultrasonography in Obstetrics and Gynecology.

Bacalbasa N.,Carol Davila University of Medicine and Pharmacy | Balescu I.,Ponderas Hospital
Anticancer Research | Year: 2015

Pelvic exenteration remains one of the most aggressive gynecological surgical procedures performed for patients with locally-invasive cervical cancer, usually performed with curative intent. However, there exist patients who present in a very advanced stage of the disease, in which only a palliative surgical procedure can be performed. Although in these cases the survival benefit is minimal, performing a pelvic exenteration significantly improves the quality of life. We present the case of a 63-year-old female who was submitted to palliative pelvic exenteration for a locally invasive recurrence in the left sciatic foramen after surgically-treated cervical cancer.

Bacalbasa N.,Carol Davila University of Medicine and Pharmacy | Balescu I.,Ponderas Hospital | Terzea D.,Monza Hospital
Gineco.eu | Year: 2016

Endosalpingiosis is a rare benign gynaecologic condition characterised by the presence of epithelial inclusions resembling tubal epithelium outside the fallopian tubes. It is usually found incidentally in postmenopausal women. The ovary seems to be the most common site of the lesions; however it can develop almost in any pelvic or abdominal organ including the lymphatic structures. We present the case of a 49-year-old patient who was submitted to surgery for bilateral ovarian tumors strongly resembling to malignant tumors. A total hysterectomy with bilateral adnexectomy, pelvic lymph node dissection and omentectomy were performed. The histopathological studies revealed the presence of bilateral ovarian endosalpingiosis associated with lymph node involvement. © 2016 Romanian Society of Ultrasonography in Obstetrics and Gynecology.

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