The Technical University of Valencia is a Spanish university located in Valencia, with a focus on science and technology. It was founded in 1968 as the Higher Polytechnic School of Valencia and became a university in 1971, but some of its schools are more than 100 years old. Wikipedia.
Merino E.,Polytechnic University of Valencia
Chemical Society Reviews | Year: 2011
Azobenzenes are ubiquitous motifs very important in many areas of science. Azo compounds display crucial properties for important applications, mainly for the chemical industry. Because of their discovery, the main application of aromatic azo compounds has been their use as dyes. These compounds are excellent candidates to function as molecular switches because of their efficient cis-trans isomerization in the presence of appropriate radiation. The classical methods for the synthesis of azo compounds are the azo coupling reaction (coupling of diazonium salts with activated aromatic compounds), the Mills reaction (reaction between aromatic nitroso derivatives and anilines) and the Wallach reaction (transformation of azoxybenzenes into 4-hydroxy substituted azoderivatives in acid media). More recently, other preparative methods have been reported. This critical review covers the various synthetic methods reported on azo compounds with special emphasis on the more recent ones and their mechanistic aspects (170 references). © 2011 The Royal Society of Chemistry. Source
Stratakis M.,University of Crete |
Garcia H.,Polytechnic University of Valencia
Chemical Reviews | Year: 2012
Recent achievements in the activation of dihydrogen, epoxides, alcohols, carbonyl compounds, alkynes, hydrosilanes, or boron hydrides, and on CO 2 fixation, C-C crosscoupling reactions, hydrogen transfer catalysis, are presented. Hardacre and co-workers used heterogenized Au nanoparticles supported on silica to achieve good to excellent selectivity in the benzylation of substituted benzenes with benzyl alcohol. Ying and co-workers used successfully a heterogeneous air- and water-stable reusable PbS-supported gold catalyst for the three-component coupling reaction. Keane and co-workers studied in detail the influence of support and particle size on activity and selectivity regarding the hydrogenation of mdinitrobenzene and chloronitrobenzene. Hii and co-workers developed a flow reactor for the highly selective direct alkylation of amines by alcohols using Au/TiO 2 as catalyst, without the requirement for an inert atmosphere or base. Source
Blasco T.,Polytechnic University of Valencia
Chemical Society Reviews | Year: 2010
This tutorial review intends to show the possibilities of in situ solid state NMR spectroscopy in the elucidation of reaction mechanisms and the nature of the active sites in heterogeneous catalysis. After a brief overview of the more usual experimental devices used for in situ solid state NMR spectroscopy measurements, some examples of applications taken from the recent literature will be presented. It will be shown that in situ NMR spectroscopy allows: (i) the identification of stable intermediates and transient species using indirect methods, (ii) to prove shape selectivity in zeolites, (iii) the study of reaction kinetics, and (iv) the determination of the nature and the role played by the active sites in a catalytic reaction. The approaches and methodology used to get this information will be illustrated here summarizing the most relevant contributions on the investigation of the mechanisms of a series of reactions of industrial interest: aromatization of alkanes on bifunctional catalysts, carbonylation reaction of methanol with carbon monoxide, ethylbenzene disproportionation, and the Beckmann rearrangement reaction. Special attention is paid to the research carried out on the role played by carbenium ions and alkoxy as intermediate species in the transformation of hydrocarbon molecules on solid acid catalysts. © 2010 The Royal Society of Chemistry. Source
Higher Council Of Scientific Research Csic and Polytechnic University of Valencia | Date: 2015-06-19
This invention refers to a microporous crystalline material of zeolitic nature that has, in its calcined state and in the absence of defects in its crystalline matrix manifested by the presence of silanols, the empirical formula
Consejo Superior De Investigaciones Cientificas, Autonomous University of Madrid and Polytechnic University of Valencia | Date: 2015-06-16
This invention relates to a compound that induces or activates telomerase activity based on the nucleotide sequence of the GSE 24.2 fragment of dyskerin or the protein or peptide sequence encoded by said nucleotide sequence. Another part of the invention relates to vectors that comprise said sequence and cells transformed thereby, and pharmaceutical compositions that contain all these elements. These compositions may be used in the treatment of diseases from the following group: ageing or acceleration of ageing, neurodegenerative diseases and dyskeratosis congenita.