Bozo L.,POLIS University |
Allkja S.,Altea and Geo Studio 2000 LTD
Geotechnical Engineering for Infrastructure and Development - Proceedings of the XVI European Conference on Soil Mechanics and Geotechnical Engineering, ECSMGE 2015 | Year: 2015
Albania is a small country (28000km2) and with 3,5million habitants. Before 1990 in Albania was very developed some economical branches as in energy, in mines, métallurgic, mechanical, chemical, textile, nutritive industries. Also we had not much developed infrastructure of roads bur very well irrigation system with about 600 water reserved. After 1990 the great part of these activities was destroied, or abandoned to create zones with enormous pollution. In other part the big emigration and "free" movement of the population was created a chaos (confusion) on the environment's management. So today, in Albania, we have more and serious problems in the environment field. In this paper we would like to evidence some of these problems, what politics must take for their solution, how is tied geotechnics and geo-environment with these politics oriented not only to bring in normality the environment, but to sure a stable development of the country. Also we wont to present the experience of the Polis University which in the didactic, research and scientific planes can resolved these problems. © The authors and ICE Publishing: All rights reserved, 2015.
Righi A.,University of Bologna |
Righi A.,University of Turin |
Agati P.,University of Bologna |
Sisto A.,POLIS University |
And 8 more authors.
Human Pathology | Year: 2012
It is difficult to evaluate the recurrence and progression potential of pituitary adenomas at presentation. The World Health Organization classification of endocrine tumors suggests that invasion of the surrounding structures, size at presentation, an elevated mitotic index, a Ki-67 labeling index higher than 3%, and extensive p53 expression are indicators of aggressive behavior. Nevertheless, Ki-67 and p53 labeling index evaluation is subject to interobserver variability, and their cutoff values are controversial. In the present study, the prognostic value of Ki-67 and p53 protein labeling indices and their correlation with clinical and radiologic parameters were evaluated using digital image analysis in a series of 166 pituitary adenomas in patients having undergone a follow-up of at least 6 years to evaluate the impact on the recurrence and progression potential of pituitary adenomas. The data were analyzed using the receiver operating characteristic curve and classification and regression tree analysis. The results showed that, in the unstratified data set, the commonly used threshold of the Ki-67 index of 3% has a high specificity (89.5%) but a low sensitivity (53.8%). Unsatisfactory performance results were obtained by performing receiver operating characteristic curve analysis on the p53 labeling index. On the contrary, the classification and regression tree analysis-derived tree demonstrated that each pituitary adenoma subtype has specific prognostic factors. Specifically, the Ki-67 labeling index is a useful prognostic factor in nonfunctioning, adrenocorticotropin, and prolactin adenomas, but with different thresholds. In conclusion, our study emphasizes that the term pituitary adenomas includes different types of tumors, each one having specific prognostic factors. © 2012 Elsevier Inc.
Agency: European Commission | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2014 | Award Amount: 499.50K | Year: 2015
Traffic Safety Culture (TraSaCu) aims at developing a cultural approach in road traffic safety research and accident prevention. Traditional approaches to traffic safety shall be complemented by a cultural perspective which has emerged recently in safety research and prevention. Safety culture has been identified as an important factor of road safety as it helps understanding and explaining the typical patterns of risk perception and risk taking that prevail in different national, regional or local traffic systems as well as their relationships with numbers and forms of accidents. A weak safety culture produce higher numbers of accidents which are more severe. A strong safety culture helps reducing the number of accidents as well as mitigating their severity. It strengthens safety relevant attitudes and behaviour and it is also a condition for making road safety measures more effective. According to a working definition of the US Department of Transportation Safety Council (US DOT), traffic safety culture is defined as the shared values, actions, and behaviours that demonstrate a commitment to safety over competing goals and demands. However, a unified concept of safety culture still does not exist. Therefore, the project will elaborate an empirically grounded and theoretically adequate concept of traffic safety culture, based on this definition by conducting a number of case studies of different traffic safety cultures across Europe. It focuses on the safety cultures that emerge under different institutional, demographic and topographical conditions and their influence on the numbers and forms of accidents. Research focuses on the culturally mediated interaction between traffic participants and their environment in terms of the cultural patterns of risk taking and risk perception. It also looks at those cultural elements that can be changed easily in order to improve road safety of the investigated traffic systems.
Ippoliti R.,POLIS University
Value in Health | Year: 2013
Clinical research is a specific phase of pharmaceutical industry's production process in which companies test candidate drugs on patients to collect clinical evidence about safety and effectiveness. Information is essential to obtain manufacturing authorization from the national drug agency and, in this way, make profits on the market. Considering this activity, however, the public stakeholder has to face a conflict of interests. On the one side, there is society's necessity to make advances in medicine and, of course, to promote pharmaceutical companies' investments in this specific phase (new generation). On the other side, there is the duty to protect patients involved in these experimental treatments (old generation). To abide by this moral duty, a protection system was developed through the years, based on two legal institutions: informed consent and institutional review board. How should an efficient protection system that would take human experimentation into account be shaped? Would it be possible for the national protection system of patients' rights to affect the choice of whether to develop a clinical trial in a given country or not? Looking at Europe and considering a protection system that is shaped around institutional review boards, this article is an empirical work that tries to give answers to these open questions. It shows how a protection system that can minimize the time necessary to start a trial can positively affect pharmaceutical clinical research, that is, the choice of pharmaceutical companies to start innovative medical treatments in a given country. © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Publishedby Elsevier Inc.
Leitao A.,POLIS University |
Inverse Problems | Year: 2016
In this article we combine the projective Landweber method, recently proposed by the present authors, with Kaczmarz's method for solving systems of nonlinear ill-posed equations. The underlying assumption used in this work is the tangential cone condition. We show that the proposed iteration is a convergent regularization method. Numerical tests are presented for a nonlinear inverse problem related to the Dirichlet-to-Neumann map, indicating a superior performance of the proposed method when compared with other well established iterations. Our preliminary investigation indicates that the resulting iteration is a promising alternative for computing stable solutions of large scale systems of nonlinear ill-posed equations. © 2016 IOP Publishing Ltd.
Guri M.,POLIS University
Civil-Comp Proceedings | Year: 2013
The compressibility characteristics of different soil types can be described using several parameters. Even though soil does not behave as a completely elastic material, due to practical reasons they can be considered and modelled as springs or as an elastic space and due to the selected model we also assess the soil properties to use. Despite the above two models, the soil can also be modelled as a combined system with springs and dampers. This paper describes and discusses the methods used to assess and evaluate the compressibility properties of soils using in situ and laboratory tests. In order to make a reliable and useful modelling of the soil, an extensive geotechnical investigation of soil parameters is needed. In this study we treat several methods to evaluate these soils and to assess their properties. A comparison is done between soil compressibility properties defined and selected using different methods, and the soil compressibility properties are correlated with the other basic properties used to describe or to classify soils. Another aspect of the study is the evaluation of the relationship between the limit states that occur in the structure and the foundation types and systems used. Using some examples we attempt to see what is the effect of the soil compressibility properties on the calculation model and on the soil structure interaction. This is done for the static loading condition only. © Civil-Comp Press, 2013.
Bozo L.,POLIS University |
Procedia Engineering | Year: 2016
The road Vlora - Saranda passes in mountainous terrain and near Jon's littoral. This national road is very important because they made connection between sea side cities Vlora, Himara, Saranda etc. This zone has marvelous natural beautiful and historical and cultural riches. This is the mean road which serve for the development of the littoral tourism in Jon sea. Since 1914, time when is constructed this road, in the zone of Dukat (about 7 km length), continually was appeared problems of instability of slopes, landslides which time by time had damaged the road. Many times engineering measures to stabilize situation was undertaken. Nevertheless the road continues damaged by phenomena's of loss of stability and landslides. In this paper we would like to present our study about this phenomenon, to find the causes of continually landslide and which can be the main factor of instabilities. Also we want to take some recommendation about engineering measures to stabilize the situation. © 2016 The Authors. Published by Elsevier B.V.
Falavigna G.,CNR Institute for Economic Research on Firms and Growth |
Ippoliti R.,Hospital Ss Antonio E Biagio E Cesare Arrigo Structure Of Scientific Promotion |
Ippoliti R.,POLIS University |
Manello A.,CNR Institute for Economic Research on Firms and Growth
Health Care Management Science | Year: 2013
The present study considers the Italian healthcare system, investigating the aspects that might affect the efficiency of Italian hospitals. The authors analyze what influences a specific definition of efficiency, which is calculated maximizing healthcare production but minimizing potential financial losses. In other words, this work considers efficient each hospital which is able to maximize the production of medical treatments while complying, at the same time, with budget constraints. Hence, the results of this paper are twofold: from the organizational point of view, they underline the need for rebalancing the various administrative levels of hospitals; from the technical point of view, a more coherent model is proposed in order to account for all the aspects of the healthcare industry. © 2012 Springer Science+Business Media New York.
Di Novi C.,POLIS University
Health economics | Year: 2010
This paper employs the Behavioral Risk Factor Surveillance System (2001) data in conjunction with the Environmental Protection Agency's Air Quality System data to investigate how air pollution caused by motor vehicle emissions affects the likelihood of good health and the amount of health investments. Models are estimated using three different measures of overall health: a measure of self-assessed health and two health outcome indicators (asthma and blood pressure). A multivariate probit approach is used to estimate recursive systems of equations for self-assessed health, health outcomes and life-styles. The most interesting result concerns the influence of pollution on health-improving life-style choices: only if traffic pollution is in the 'satisfactory range' (AQI level at or below 100), individuals will have incentive to invest in health. Copyright © 2009 John Wiley & Sons, Ltd.
Ferrero M.,POLIS University
Peace Economics, Peace Science and Public Policy | Year: 2013
This note places mass killing in a continuum of actions that a ruling power can take to remove an unwanted group from a society; that is, it views extermination as a means to an end, and it assumes that rulers are rational and will choose the combination of means that can achieve their goal at the minimum cost to themselves. The means are assimilation into the general society, physical removal from view (through either deportation within the country or exile from the country), and extermination. The note develops a simple model of input choice geared to cost minimization and then finds encouraging support from the historical evidence on communist regimes. © 2013 by Walter de Gruyter Berlin Boston.