el Pla del Penedès, Spain
el Pla del Penedès, Spain

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Benito A.,Hospital Pla | Haro G.,Hospital Provincial | Fornes T.,Clinica del Sistema Nervioso Central | Mateu C.,Grupo de Investigacion TXP
Adicciones | Year: 2012

The aim was to analyze the relationship between Cloninger's dimensions and Personality Disorders (PD) (with DSM-IV criteria) in opiate dependents. The study was Cross-sectional. The sampling of 196 patients with opiate dependence was consecutive. All were receiving treatment in an inpatient detoxification unit. Cloninger's Temperament and Character Inventory (TCI), International Personality Disorders Examination (IPDE) and a Substance Use Questionnaire were used. Character's dimensions as Self-directness and Cooperation were related with PD when scored low. Opposite to Cloninger descriptions, high scores of Self-transcendence were related with presence of PD. Related to temperamental dimensions, cluster A was related with low scores of Reward Dependence (RD) and cluster C with high scores of Harm Avoidance (HA). Otherwise, in cluster B, while Borderline PD had high scores of Novelty Seeking (as high HA), the Antisocial PD only were related to low scores of RD. RD dimension seems useful to differ from presence or absence of Antisocial PD, also when alcohol consumption is considered. Cloninger's Model of Personality is useful in drug dependents for the definition of the different PD, as well as for probable PD's aggregation. This model also helps to create subtypes in opiate dependents as the antisocial or type II.


Mateu C.,Hospital Of La Ribera | Benito A.,Hospital Pla | Pena-Garijo J.,Jaume I University | Ferrer J.,Hospital General Universitario Of Valencia | Haro G.,Consorcio Hospital Provincial Of Castellon
Health and Addictions / Salud y Drogas | Year: 2010

Introduction: Patients with substance abuse show some common personality characteristics but it has not been possible to demonstrate that the presence of these characteristics determines their addiction. In the present investigation we tried to analyze cerebral activity in a group of patients with dependency on opiates and Borderline Personality Disorder (BPD) or Personality Disorder Not Otherwise Specified (PDNOS). Method: Cross-sectional study of an observational type with descriptive and analytical components in a sample of 25 subjects with dual pathology in comparision with 17 healthy subjects. SPECT images were acquired using 99mTC-ECD (Tcm-Ethyl Cysteinate Die-thylester) by intravenous route as a radioactive tracer. Data were analyzed with the software package Entegra. Results: When we compared subjects with PDNOS to the control group, statistically significant differences in the number of counts registered in the thalamus were noticeable (χ̄=9043.26; p<0.029), which demonstrates less thalamic activity in PDNOS subjects with respect to healthy subjects. Statistically significant differences in the rest of comparisons between groups were not observed. Conclusion: Pacients with PDNOS and adiction show a thalamic hypoactivity pattern. This conclusion could help us in the understanding of the pathogenesis of this disorder and its differentiation from the other PD, like BPD, at least in patients with dual pathology. © Health and Addictions / Salud y Drogas.


PubMed | Hospital Pla
Type: Journal Article | Journal: Adicciones | Year: 2012

The aim was to analyze the relationship between Cloningers dimensions and Personality Disorders (PD) (with DSM-IV criteria) in opiate dependents. The study was Cross-sectional. The sampling of 196 patients with opiate dependence was consecutive. All were receiving treatment in an inpatient detoxification unit. Cloningers Temperament and Character Inventory (TCI), International Personality Disorders Examination (IPDE) and a Substance Use Questionnaire were used. Characters dimensions as Self-directness and Cooperation were related with PD when scored low. Opposite to Cloninger descriptions, high scores of Self-transcendence were related with presence of PD. Related to temperamental dimensions, cluster A was related with low scores of Reward Dependence (RD) and cluster C with high scores of Harm Avoidance (HA). Otherwise, in cluster B, while Borderline PD had high scores of Novelty Seeking (as high HA), the Antisocial PD only were related to low scores of RD. RD dimension seems useful to differ from presence or absence of Antisocial PD, also when alcohol consumption is considered. Cloningers Model of Personality is useful in drug dependents for the definition of the different PD, as well as for probable PDs aggregation. This model also helps to create subtypes in opiate dependents as the antisocial or type II.

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