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Li Q.,PLA Chengdu Military Area Command General Hospital | Deng D.,PLA Chengdu Military Area Command General Hospital | Tao J.,PLA Chengdu Military Area Command General Hospital | Wu X.,PLA Chengdu Military Area Command General Hospital | And 3 more authors.
Genetics and Molecular Research | Year: 2015

We investigated wound tract extension of traumatic gunshot wounds in limb soft tissues as well as wound tract sonographic features and change-patterns when the limb position was changed. The experimental animals included 8 healthy crossbred pigs in the Chengdu plain region. Chinese Type 53 Carbine was used to establish the gunshot wound model of porcine soft tissues. Gunshot-injured zones in the soft tissues were dynamically observed at different time points using ultrasonic technology. Pathological examinations were performed for the corresponding regions for comparison and analysis. The internal echo of the wound tract was a pipe-like echo that changed over time. The wound tract extension changed with postural changes. The gas echo extended along the inside of the wound track, surrounding the fascia to further tissues. Ultrasonic imaging of gunshot wounds in pig soft tissues shows specific characteristics. The application of ultrasound technology may provide important imaging protection for gunshot wound debridement and postoperative unobstructed drainage, helping to improve the judgment and treatment of limb gunshot injuries. © FUNPEC-RP.

Luo C.,University of Electronic Science and Technology of China | Tu S.,University of Electronic Science and Technology of China | Tu S.,PLA Chengdu Military Area Command General Hospital | Peng Y.,University of Electronic Science and Technology of China | And 7 more authors.
Neural Plasticity | Year: 2014

Musicians undergoing long-term musical training show improved emotional and cognitive function, which suggests the presence of neuroplasticity. The structural and functional impacts of the human brain have been observed in musicians. In this study, we used data-driven functional connectivity analysis to map local and distant functional connectivity in resting-state functional magnetic resonance imaging data from 28 professional musicians and 28 nonmusicians. Compared with nonmusicians, musicians exhibited significantly greater local functional connectivity density in 10 regions, including the bilateral dorsal anterior cingulate cortex, anterior insula, and anterior temporoparietal junction. A distant functional connectivity analysis demonstrated that most of these regions were included in salience system, which is associated with high-level cognitive control and fundamental attentional process. Additionally, musicians had significantly greater functional integration in this system, especially for connections to the left insula. Increased functional connectivity between the left insula and right temporoparietal junction may be a response to long-term musical training. Our findings indicate that the improvement of salience network is involved in musical training. The salience system may represent a new avenue for exploration regarding the underlying foundations of enhanced higher-level cognitive processes in musicians. © 2014 Cheng Luo et al.

Zhang C.,PLA Chengdu Military Area Command General Hospital | Zhang C.,Sichuan University | Huang Z.,Sichuan University | Liao X.,Sichuan University | And 2 more authors.
Journal of Coatings Technology Research | Year: 2012

In this study, co-doped ZnO rod arrays with wurtzite crystal structure were successfully prepared on zinc substrate by the co-precipitation method. The results of crystal analysis indicated that the dopant Co 2+ was incorporated into ZnO crystal. Photoluminescence (PL) spectra and magnetization curves proved that their PL intensity and ferromagnetism were increased with the increase of Co 2+ concentrations in a ZnO host. Current-voltage characteristic curves of Co-doped ZnO rod arrays indicated that as-prepared samples were n-type semiconductors. Co-doped ZnO rod arrays could be envisioned to detect diseases and bacteria based on these properties. © 2012 ACA and OCCA.

He C.,University of Sichuan | He C.,PLA Chengdu Military Area Command General Hospital | Yang Z.-G.,University of Sichuan | Chu Z.-G.,University of Sichuan | And 7 more authors.
Cardiovascular Diabetology | Year: 2010

Background: Plaque morphology directly correlates with risk of embolism and the recently developed dual-source computed tomography angiography (DSCTA) may help to detect plaques more precisely. The aim of our study was to evaluate the prevalence and morphology of carotid and cerebrovascular atherosclerotic plaques in patients with symptomatic type 2 diabetes mellitus (DM) by DSCTA.Methods: From July 2009 to August 2010, DSCTA was prospectively performed in 125 consecutive patients with symptomatic type 2 DM. We retrospectively analyzed plaque type, distribution, and extensive and obstructive natures were determined for each segment for all patients.Results: Atherosclerotic plaques were detected in 114 (91.2%) patients. Relatively more noncalcified (45%) and calcified (39%) plaques and less mixed (16%) plaques were observed (p < 0.001). Noncalcified plaques were found mainly in the intracranial arteries (81.8%), mixed plaques in the intracranial arteries (25.2%) and intracranial internal carotid artery (ICA) (56.1%). Calcified plaques were found mainly in the intracranial ICA (65.9%) and extracranial arteries (28.2%) (for all, p < 0.001). Extension of plaques from the 1stto 5thsegments was observed in 67 (58.8%) patients and from the 6thto 10thsegments in 35 (30.7%) patients. The most common site of all detected plaques was the cavernous segment. Regarding stenosis, there were significantly more nonobstructive than obstructive stenosis (91% vs. 9%, p < 0.001).Conclusion: DSCTA detected a high prevalence of plaques in patients with symptomatic type 2 DM. A relatively high proportion of plaques were noncalcified, as well as with nonobstructive stenosis. The distribution of plaques was extensive, with the cavernous portion of ICA being the most common site. © 2010 He et al; licensee BioMed Central Ltd.

Yu S.,Chongqing Medical University | Gu J.,Chongqing Medical University | Wang H.G.,Chongqing Medical University | Wang Q.X.,PLA Chengdu Military Area Command General Hospital | And 7 more authors.
Clinical Immunology | Year: 2011

Enterohemorrhagic E. coli (EHEC) causes severe diseases in humans and animals via the production of Shiga toxins, and injection of effectors into epithelia using type III secretion system (TTSS). E. coli secreted protein A (EspA) forms the filamentous conduits of TTSS, which extends into the translocation pore embedded in host cell membranes and aids in the transportation of bacterial effectors. In addition, EspA is closely associated with initial bacterial adhesion and the formation of biofilms. EspA in its various forms elicits protective immune responses, although the epitope responsible has not to be identified. Here we report the presence of a linear, immunogenic, conserved and partially protective epitope E07 (100Lys-120Val) on EspA, which is recognized by the novel monoclonal antibody 1H10. This antibody blocks EHEC-induced actin polymerization and confers protection in mice. These findings provide a better understanding of EspA-induced immune responses and could lead to epitope-based vaccines and antibody-based therapies. © 2010 Elsevier Inc.

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