Tang Z.,303 Hospital of PLA
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery | Year: 2013
To investigate the clinical features and treatment options of ossifying fibroma of paranasal sinuses. A retrospective evaluation of twenty-three patients with ossifying fibroma of paranasal sinuses was presented. The choice of surgical operations on ossifying fibroma of paranasal sinuses was mainly decided by the location and area of ossifying fibroma. Radical operations were performed in twenty-one patients, ten of them through a lateral rhinotomy approach, eight through nasal endoscopic approach, four through Caldwell-Luc approach, one through coronal approach. Two patients were performed partial resection by nasal endoscopic surgery. Diagnoses of all cases were confirmed by pathology. All patients outcomes were successful, no serious complication from the surgical technique occurred. Twenty cases were followed-up for six months to nineteen years. Two patients recurred. Earlier diagnosis, CT scan, proper surgery, and radical resection are the keys to the treatment of ossifying fibroma of paranasal sinuses.
Chen S.-W.,Southern Medical University |
Tang Z.,303 Hospital of PLA |
Liu L.,Southern Medical University |
Zou Z.-P.,Southern Medical University |
And 2 more authors.
Medical Journal of Chinese People's Liberation Army | Year: 2015
Objective To investigate the effect of Xiaoer Fuxie Waifu powder on intestinal Cajal cells (ICC) and the expression of vasoactive peptide receptor 1 (VIP-R1) in rats with diarrhea. Methods Thirty Wistar rats were divided randomly into three groups: control group, model group, and treatment group (10 each). Folium sennae (2ml/100g) was gavaged to reproduce the diarrheal model. Xiaoer Fuxie Waifu powder was applied topically in the treatment group. Transmission electron microscope was used to observe the changes in ultrastructure of ICC after application of the drug. Immunohistochemistry was used to observe the distribution of VIP-R1 in the intestine of diarrheic rats. RT-PCR and Western blotting were used to determine the expressions of mRNA and protein of VIP-R1. Results The ultrastructure of ICC showed that the drug treatment could normalize the cellular morphology and gap junction. VIP-R1 was found to be distributed mainly between circular muscle and longitudinal muscle, in the myenteric nerve plexus of the small intestine, and was found around the epithelial cells in the mucosal layer of the colon and lamina propria cells. Xiaoer Fuxie Waifu powder inhibited the secretion of VIP-R1 and down-regulated the mRNA and protein expression of VIP-R1. Conclusion Xiaoer Fuxie Waifu powder can repair the injured ICC of diarrheic rats and cure diarrhea by down-regulating the expression of VIP-R1. © 2015 People's Military Medical Press.
Yang T.-M.,303 Hospital of PLA |
Wei Q.-Z.,U.S. Food and Drug Administration |
Lu W.-Z.,Respiratory Diseases |
Fan X.-L.,303 Hospital of PLA
Journal of the College of Physicians and Surgeons Pakistan | Year: 2016
Objective: To compare the ventilatory effects of the three-way laryngeal mask airway (TLMA) and tracheal tube (TT) on hemodynamics, respiratory function, and stress responses in a canine model during bronchoalveolar lavage (BAL). Study Design: Experimental study. Place and Duration of Study: The 303rd Hospital of the Chinese People's Liberation Army in May 2013. Methodology: Sixteen dogs were divided into two groups. MAP, SpO2 and HR were recorded before anesthesia (T0), immediately before intubation (T1), during intubation (T2), at 3 (T3) and 10 (T4) minutes after mechanical ventilation, at 10 (T5), 20 (T6), and 30 (T7) minutes during the course of BAL, during extubation (T8), and 3 minutes after extubation (T9). Tidal volume, peak inspiratory airway pressure, and expiratory CO2 pressure were recorded at time points T2, T5, T6, T7, and T8. Stress responses variables, including epinephrine and norepinephrine levels, were examined at time points T0, T2, T3, T5, T8, and T9. Results: BAL was successfully completed in all animals. In comparison to the TT, the TLMA was capable of maintaining hemodynamic stability and ventilation (p < 0.05), and producing less stress responses (p < 0.05). Conclusion: In a canine model, ventilation with the TLMA was better than the TT during BAL in terms of maintaining effective ventilation and stable hemodynamics, and producing less stress responses.
Li H.,Mianyang Central Hospital |
Li H.,Southern Medical University |
Wang J.,Mianyang Central Hospital |
Ouyang B.,Peoples Hospital of Jiangsu Province |
And 8 more authors.
International Journal of Clinical and Experimental Medicine | Year: 2016
Background: This study aims to investigate the attitude and knowledge of Chinese physicians towards obstructive sleep apnea syndrome (OSAS). Methods: Seven hospitals in China including 580 doctors were organized to participate in this study. In this present investigation, a self-reported questionnaire that aims to assess the attitude and knowledge of physicians towards OSAS was used. Results: A total of 563 questionnaires were returned. Among the 560 respondents who completed the questionnaires, 532 (95%) respondents thought snoring might be a disease and 507 (80.5%) respondents knew what OSAS is. Respondents in the relevant professional group (RP group) were more familiar with OSAS than those in the non-related professional group (NRP group) (P=0.027), and both groups strongly agreed on these two statements: “OSAS needs to be treated aggressively or given attention” and “knowledge of OSAS needs to be enhanced” (P > 0.05). Mean OSAS knowledge score of physicians was 44.87 ± 20.64. The RP group had a higher score than the NRP group, P=0.009. Based on location, Southern hospitals had a higher score than Northern hospitals (P=0.026), while Western hospitals had a higher score than Eastern hospitals (P=0.006). Tertiary level hospitals had a higher score compared with lower-level hospitals (P=0.000). Respondents had higher scores when a sleep center was present in the hospital (P=0.012). Respondents with higher professional titles had higher scores (P=0.000). Treatments from highest to lowest scores were as follows: weight loss, quit smoking and alcohol, continuous positive airway pressure (CPAP), avoid fatigue, surgery and drugs. Conclusions: Doctors recognized that snoring might be a disease and they recommended aggressive treatment or give attention for OSAS. However, their knowledge of OSAS was poor. They were willing to further their knowledge of OSAS. © 2016, E-Century Publishing Corporation. All rights reserved.
Chen Y.-S.,Chongqing Medical University |
Kong P.-Y.,Chongqing Medical University |
Zeng D.-F.,Chongqing Medical University |
Li J.-P.,Chongqing Medical University |
And 8 more authors.
Medical Journal of Chinese People's Liberation Army | Year: 2013
Objective To investigate the therapeutic effect of autologous peripheral blood stem cell transplantation (APBSCT) in combination with rituximab in treatment of CD20+ B cellulous non-Hodgkin's lymphoma (B-NHL). Methods Sixty patients with CD20+ aggressive or refractory and recurrent B-NHL and treated with APBSCT in our department from Jan. 2005 to Jan. 2011 were admitted. All the subjects were divided into 2 groups according to their own choice: 25 patients received rituximab treatment (treatment group) and 35 patients were treated without rituximab treatment (control group). All patients underwent chemotherapy and APBSCT. For patients in treatment group, rituximab was used with CHOP before collecting the stem cells and after the transplantation. After transplantation, rituximab and IL-2 were used in treatment group every 3-6 months as maintenance treatment. Results No side effect was observed during the use of rituximab either before or after transplantation. The mononuclear cell count in treatment and control group was (8.2±2.9)×108/kg and (8.4±3.9)×108/kg (P=0.822), respectively; CD34+ cell count was (12.3±12.7)×106/kg and (13.2±13.9)×106/kg (P=0.799), respectively. Haemopoiesis reconstruction was successfully achieved in the patients of treatment group, while 3 patients in control group failed to have haemopoiesis reconstruction. No significant difference was found between two groups on the recovery time of neutrophilic granulocytes and platelets. All patients achieved complete remission. The average follow-up time was 22 months. The disease relapsed in two patients in treatment group and six in control group. The 3-year overall survival rate in treatment group (91.6%) was a little higher than that in control group (69.5%, P=0.060). Conclusion To patients of CD20+ B lymphoma, the use of rituximab shows no side effect before or after collection of stem cell and hemopoiesis reconstruction, and the overall survival rate may be improved.