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Andover, MA, United States

Patent
Physical Sciences, Inc | Date: 2015-09-02

A method of operating a Tm:doped fiber amplifier including selecting a length of Tm:doped optical fiber to be less than one hundred meters, doping the optical fiber with active ions at a doping level of greater than one percent, optically pumping the doped optical fiber with a first laser beam having a wavelength longer than the wavelength where a maximum absorption cross section is provided by the active ions, and creating a population inversion between two active ion energy levels with the first laser beam, the active ions providing a gain to a second laser beam.


Patent
Physical Sciences, Inc | Date: 2015-07-09

A handheld optical coherence tomography imaging and tissue sampling system and method of imaging and sampling a tissue is disclosed. The method includes inserting a catheter probe into a biopsy needle. The biopsy needle can be attached to a hand-held scanning and sampling device. The biopsy needle is maneuvered to an investigation site. A three-dimensional image of the tissue at the investigation site is captured with the catheter probe.


Patent
Physical Sciences, Inc | Date: 2014-11-13

A product critical temperature during freeze drying is determined. The product is imaged using optical coherence tomography (OCT). The product is freeze dried while the temperature of the product is measured. The product critical temperature is the temperature at which a product structure event occurs during freeze drying.


Patent
Physical Sciences, Inc | Date: 2014-02-27

An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina. The first scanning device is configured to move the first imaging beam along the retina in the slow axis of the SLO mode to acquire the first image and (ii) to move the second imaging beam along the retina in the fast axis of the OCT mode to acquire the second image.


Patent
Physical Sciences, Inc | Date: 2015-09-08

A method for producing a coated powder including homogeneously mixing an electrochemically active material including electrochemically active particles with nanosize particles in a ratio determined by the surface area of the electrochemically active particles to form a homogeneous powder, adding a polymer and mixing to form a homogeneous solid mixture, adding a solvent to dissolve the polymer and form a viscous slurry, mixing the viscous slurry, and drying the viscous slurry to cause the nanosize particles to become localized adjacent to an outer surface of the electrochemically active particles with the polymer maintaining the proximity between the nanosize conductive particles and the outer surface of the electrochemically active particles.

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