Carlsbad, CA, United States
Carlsbad, CA, United States

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A method and apparatus irradiates a surface with at least one light beam emitted from an emission surface of an optical element. The at least one light beam has a cross-sectional area greater than about 2 cm2, and a time-averaged irradiance in a range of about 10 mW/cm2 to about 10 W/cm2 across the cross-sectional area. The at least one light beam can include a plurality of pulses having a temporal pulsewidth in a range between about 0.1 millisecond and about 150 seconds, and having a time-averaged irradiance in a range between about 1 mW/cm2 and about 100 W/cm2.


A method and apparatus irradiates a surface with at least one light beam emitted from an emission surface of an optical element. The at least one light beam has a cross-sectional area greater than about 2 cm2, and a time-averaged irradiance in a range of about 10 mW/cm2 to about 10 W/cm2 across the cross-sectional area. The at least one light beam can include a plurality of pulses having a temporal pulsewidth in a range between about 0.1 millisecond and about 150 seconds, and having a time-averaged irradiance in a range between about 1 mW/cm2 and about 100 W/cm2.


Patent
Photothera Inc. | Date: 2012-08-22

An apparatus is wearable by a patient for treating the patients brain. The apparatus includes a body which covers at least a portion of the patients scalp when the apparatus is worn by the patient. The apparatus further includes a plurality of elements. Each element has a first portion which conforms to a corresponding portion of the patients scalp when the apparatus is worn by the patient. Each element has a second portion which conforms to a light source removably contacting the element. Each element is substantially transmissive to light from the light source to irradiate at least a portion of the patients brain


Patent
Photothera Inc. | Date: 2012-08-22

An apparatus is wearable by a patient for treating the patients brain. The apparatus includes a body which covers at least a portion of the patients scalp when the apparatus is worn by the patient. The apparatus further includes a plurality of elements. Each element has a first portion which conforms to a corresponding portion of the patients scalp when the apparatus is worn by the patient. Each element has a second portion which conforms to a light source removably contacting the element. Each element is substantially transmissive to light from the light source to irradiate at least a portion of the patients brain


A method and apparatus irradiates a surface with at least one light beam emitted from an emission surface of an optical element. The at least one light beam has a cross-sectional area greater than about 2 cm2, and a time-averaged irradiance in a range of about 10 mW/cm2 to about 10 W/cm2 across the cross-sectional area. The at least one light beam can include a plurality of pulses having a temporal pulsewidth in a range between about 0.1 millisecond and about 150 seconds, and having a time-averaged irradiance in a range between about 1 mW/cm2 and about 100 W/cm2.


Methods of enhancing stem cell therapy through the administration of low level light energy are provided in several embodiments. Some embodiments comprise irradiating stem cells before or after implantation at a target tissue having loss of function due to damage or disease, with a resultant increase in the efficacy of the cell therapy. In some embodiments, light energy enhances one or more of the viability, proliferation, migration or engraftment of the stem cells, thereby enhancing the therapeutic effects of the irradiated cells during cell therapy.


Patent
Photothera Inc. | Date: 2010-03-24

An optical assembly includes an output optical element having a thermally conductive and optically transmissive material and a thermal conduit in thermal communication with the output optical element and having at least one surface configured to be in thermal communication with at least one heat dissipating surface of a light delivery apparatus. The optical assembly further includes a coupling portion configured to be placed in at least two states. In a first state, the coupling portion is attached to the apparatus such that the at least one surface of the thermal conduit is in thermal communication with the at least one heat dissipating surface. In a second state, the coupling portion is detached from the apparatus after having been attached to the apparatus in the first state and in which the coupling portion is configured to prevent reattachment of the coupling portion to the apparatus.


Patent
Photothera Inc. | Date: 2012-11-14

An optical assembly includes an output optical element having a thermally conductive and optically transmissive material and a thermal conduit in thermal communication with the output optical element and having at least one surface configured to be in thermal communication with at least one heat dissipating surface of a light delivery apparatus. The optical assembly further includes a coupling portion configured to be placed in at least two states. In a first state, the coupling portion is attached to the apparatus such that the at least one surface of the thermal conduit is in thermal communication with the at least one heat dissipating surface. In a second state, the coupling portion is detached from the apparatus after having been attached to the apparatus in the first state and in which the coupling portion is configured to prevent reattachment of the coupling portion to the apparatus.


Patent
Photothera Inc. | Date: 2012-08-22

An apparatus is wearable by a patient for treating the patients brain. The apparatus includes a body which covers at least a portion of the patients scalp when the apparatus is worn by the patient. The apparatus further includes a plurality of elements. Each element has a first portion which conforms to a corresponding portion of the patients scalp when the apparatus is worn by the patient. Each element has a second portion which conforms to a light source removably contacting the element. Each element is substantially transmissive to light from the light source to irradiate at least a portion of the patients brain


Patent
Photothera Inc. | Date: 2011-06-20

A method for treating a subject having Parkinsons disease is provided. The method includes noninvasively delivering light energy having a wavelength of about 630 nanometers to about 904 nanometers to the brain of the subject. Delivering the light energy can include (i) irradiating the scalp with light energy having an incident power density less than 1000 mW/cm^(2 )and (ii) transmitting a portion of the light energy through the scalp and the skull to the brain.

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