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New Philadelphia, PA, United States

Philadelphia University , founded in 1884, is a private university in the East Falls neighborhood of Philadelphia, Pennsylvania, United States. The student body has about 3,500 students. Academic programs are divided among the College of Architecture and the Built Environment; the Kanbar College of Design, Engineering and Commerce; and the College of Science, Health and the Liberal Arts; the School of Continuing and Professional Studies; coursed are also offered via PhilaU Online. Philadelphia University awards bachelor's degrees, master's degrees and doctoral degrees. Wikipedia.


Insomnia is a common health complaint world-wide. Insomnia is a risk factor in the development of other psychological and physiological disorders. Therefore understanding the mechanisms which predispose an individual to developing insomnia has great transdiagnostic value. However, whilst it is largely accepted that a vulnerable phenotype exists there is a lack of research which aims to systematically assess the make-up of this phenotype. This review outlines the research to-date, considering familial aggregation and the genetics and psychology of stress-reactivity. A model will be presented in which negative affect (neuroticism) and genetics (5HTTLPR) are argued to lead to disrupted sleep via an increase in stress-reactivity, and further that the interaction of these variables leads to an increase in learned negative associations, which further increase the likelihood of poor sleep and the development of insomnia. Copyright © 2013 Elsevier Ltd. All rights reserved. Source


Soufi A.,Philadelphia University
Current Opinion in Genetics and Development | Year: 2014

During development, the genome adopts specific chromatin states to establish and maintain functionally distinct cell types in a well-controlled environment. A select group of transcription factors have the ability to drive the transition of the genome from a pluripotent to a more specialized chromatin state. The same set of factors can be used as reprogramming factors to reset the already established chromatin state back to pluripotency or directly to an alternative cell type. However, under the suboptimal reprogramming conditions, these factors fall short in guiding the majority of cells to their new fate. In this review, we visit the recent findings addressing the manipulation of chromatin structure to enhance the performance of transcription factors in reprogramming. The main emphasis is on the mechanisms underlying the conversion of somatic cells to pluripotency using OSKM. This review is intended to highlight the windows of opportunities for developing mechanistically based approaches to replace the phenotypically guided methods currently employed in reprogramming, in an attempt to move the field of cell conversion towards using next generation technologies. © 2014 Elsevier Ltd. Source


Patent
Philadelphia University | Date: 2014-03-17

A method for making an antibacterial fabric having resistance to laundering while maintaining its antibacterial properties.


Patent
Philadelphia University | Date: 2011-06-06

A woven article having plural weave layers comprises a plurality of electrically insulating and/or electrically conductive yarn in the warp and a plurality of electrically insulating and/or electrically conductive yarn in the weft interwoven with the yarn in the warp. An electrical function is provided by one or more circuit carriers disposed in cavities in the plural layer woven article and/or one or more functional yarn in the warp and/or the weft, wherein the circuit carrier and/or functional yarn include an electrical contact for connecting to the electrically conductive yarn in the warp and/or weft.


Patent
Philadelphia University | Date: 2010-02-15

Methods and apparatus for combating sick building syndrome include a plenum that is at least partially bounded by fabric comprising at least one naturally occurring botanically based, antimicrobial, morbidity-inducing fabric and preferably a fan for introducing air into the plenum for passage outwardly through the fabric thereby to cleanse the air of microbes contributing to sick building syndrome.

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