Pharmacy School

Vila Velha, Brazil

Pharmacy School

Vila Velha, Brazil
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NEW BRUNSWICK, N.J.--(BUSINESS WIRE)--Spectrum Pharmacy Products, a leading global manufacturer and distributor of pharmaceutical compounding chemicals, equipment and supplies, held a ribbon-cutting ceremony recently for the opening of the new Spectrum Pharmacy Institute, a 42,000 square-foot manufacturing, distribution and compounding training center located in New Brunswick, New Jersey. The Spectrum Pharmacy Institute represents an $11 million commitment the company has made to the New Brunswick community and to compounders nationally. Spectrum Pharmacy Institute’s expansion plans include the addition of approximately 50 new jobs in the New Brunswick area. Spectrum hosted New Brunswick Mayor Jim Cahill; Rutgers University Pharmacy School dignitaries; international laboratory and pharmacy suppliers; and local and regional pharmacy customers at the ribbon-cutting ceremony. Spectrum Pharmacy Products Division President, Dr. Craig A. Recatto, said, “We have been meeting the needs of compounding pharmacists for more than 40 years. We are excited to introduce this state-of-the-art facility to the local community and to pharmacists throughout the U.S. Our ribbon-cutting ceremony marks the launch of a new business phase for both Spectrum Pharmacy Products and our parent company, Spectrum Chemical.” Mayor Cahill spoke about the Spectrum Pharmacy Institute as a new part of the company’s thriving network. “This new facility takes full advantage of much of what serves as a strong economic foundation of New Brunswick, built largely on health care, manufacturing and education. It will add approximately 50 new jobs, multiplying the impact on our local economy through the money spent by the company to operate its local facilities, the money earned by its employees, and money spent by visiting pharmacists. This new expansion will help our local health care institutions provide even more of the quality services we all depend on.” Accreditation with the Ernest Mario School of Pharmacy at Rutgers University 15,000 square feet of the Spectrum Pharmacy Institute is dedicated to continuing education classrooms with the latest multimedia and AV technologies, as well as advanced laboratories, for hands-on, best practices compounding training. Compounding courses at the Spectrum Pharmacy Institute are taught by national experts and are jointly accredited with the Ernest Mario School of Pharmacy at Rutgers University. The accredited courses provide continuing education units (CEUs) that are required by states that license pharmacists and pharmacy technicians. Courses range from basic compounding techniques to sterile compounding, USP 800 compliance, hormone replacement therapy, pain management and veterinary compounding. For more information regarding Spectrum Pharmacy Institute, courses offered or class schedule, please call 800-370-6231, ext. 5479 or email Visit our continuing education page, Spectrum Pharmacy Institute. Spectrum Pharmacy Products, a division of Spectrum Chemical Manufacturing Corporation, manufactures and distributes high-quality compounding chemicals, equipment and supplies. Spectrum has been serving compounders for more than 40 years with the industry’s largest portfolio of USP/NF grade products and DEA Controlled Substances (Schedules I – V). Its bicoastal cGMP facilities are FDA registered and inspected, with additional certification to the ISO 9001:2008 standard. Spectrum is known for extensive laboratory testing with the highest standards and most modern instrumentation in the industry in both its New Jersey and California laboratories. For more information, visit Spectrum Pharmacy Institute is a 42,000-square foot pharmacy distribution, manufacturing, and training facility located in New Brunswick, New Jersey. SPI is committed to providing the finest academic learning experience in the industry. The Institute offers the latest comprehensive lecture-based and hands-on compounding education. Learning programs feature a cutting-edge multi-media, audio-visual classroom and laboratory experience, including ISO-Class 7 & 8 cleanrooms, fully functional teaching laboratories, current compounding equipment and supplies, and USP <800> compliant facilities. All courses are written and presented by subject matter experts, and all education programs are reviewed by faculty of the Ernest Mario School of Pharmacy at Rutgers University and jointly accredited with Spectrum Pharmacy Institute. For more information, visit

Iranshahi M.,Pharmacy school | Khoshangosht M.,Pharmacy school | Mohammadkhani Z.,Pharmacy school | Karimi G.,Pharmacy school
Pharmacologyonline | Year: 2011

Saffron (Crocus sativa L.) is one of the most valuable Iranian local plants and has been traditionally used as a medicine. The preventive effects of aqueous and ethanolic extracts of saffron stigma and petal were evaluated against CCl4 induced hepatotoxicity in rats. CCl4 induced fatty degeneration and vacuole formation and significantly increased the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in plasma. Treatment with aqueous and ethanolic extracts of C. sativus L., stigmas and petals significantly decreased the levels of AST and ALT in plasma. Also histopathological studies showed that aqueous and ethanolic extracts of saffron (stigma and petal) reduce the incidence of liver lesions induced by CCl4. The hepatoprotective effects of aqueous and ethanolic extracts of saffron may be due to: 1- antioxidant effects and radical scavenging 2-reduction of CCl4 metabolic activation by cytochrome P450 inhibition 3- fixation of hepatic cell membrane. This results suggested that aqueous and ethanolic extracts of saffron exhibit hepatoprotective effects against liver damages induced by CCl4 in mice.

Marcato D.G.,University Of Vila Velha Uvv | Sampaio J.D.,University Of Vila Velha Uvv | Alves E.R.B.,University Of Vila Velha Uvv | de Jesus J.S.A.,University Of Vila Velha Uvv | And 3 more authors.
Arquivos Brasileiros de Endocrinologia e Metabologia | Year: 2014

Objective: Sitting height (SH) is an important parameter in the evaluation of children with growth and pubertal disorders. Besides this, it has been viewed as a biomarker of cardiovascular risk, which is increased in adults with relatively short legs. So, the aim of this study was to evaluate the relationship between body proportions and cardiovascular risk markers in children. Subjects and methods: Eight hundred and seventeen children aged 6-13 years were evaluated. Weight, height, sitting-height (SH), sitting-height/height (SH/H), body mass index (BMI) and blood pressure (BP) were assessed and converted to standard deviation scores (SDS) for age and sex. Statistical analyses were performed. Results: There was a positive association of BMI SDS with SH and SH/H SDS (p < 0.001). Overweight children showed SH 0.8 SDS superior to eutrophic children (p < 0.001). SH SDS was also directly related to BP SDS, but this association was not independent of the association between obesity and BP when assessed by multiple regression analyzes. Conclusion: Measures of SH are strongly associated with BMI and BP in children, although the association between SH and BP is probably dependent on the association of both those variables with BMI. This is (an) important information for correct interpretation of SH values in children. © ABE&M todos os direitos reservados.

Wen Z.,Pharmacy School | Li G.,Yantai University | Lin D.-H.,Pharmacy School | Wang J.-T.,Pharmacy School | And 2 more authors.
Yaoxue Xuebao | Year: 2013

The present study is to establish Caco-2/HT29-MTX co-cultured cells and investigate the transport capability of PLGA nanoparticles with different surface chemical properties across Caco-2/HT29-MTX co-cultured cells. PLGA-NPs, mPEG-PLGA-NPs and chitosan coated PLGA-NPs were prepared by nanoprecipitation method using poly(lactic-co-glycolic acid) as carrier material with surface modified by methoxy polyethylene glycol) and chitosan. The particle size and zeta potential of nanoparticles were measured by dynamic light scattering. Coumarin 6 was used as a fluorescent marker in the transport of nanoparticles investigated by confocal laser scanning microscopy. The transport of furanodiene FDE loaded nanoparticles was quantitively determined by high performance liquid chromatography. Colchicine and nocodazole were used in the transport study to explore the involved endocytosis mechanisms of nanoparticles. Distribution of the tight junction proteins ZO-1 was also analyzed by immunofluorescence staining. The results showed that the nanoparticles dispersed uniformly. The zeta potential of PLGA-NPs was negative, the mPEG-PLGA-NPs was close to neutral and the CS-PLGA-NPs was positive. The entrapment efficiency of FDE in all nanoparticles was higher than 75%. The transport capability of mPEG-PLGA-NPs across Caco-2/HT29-MTX co-cultured cells was higher than that of PLGA-NPs and CS-PLGA-NPs. Colchicine and nocodazole could significantly decrease the transport amount of nanoparticles. mPEG-PLGA-NPs could obviously reduce the distribution of ZO-1 protein than PLGA-NPs and CS-PLGA-NPs. The transport mechanism of PLGA-NPs and mPEG-PLGA-NPs were indicated to be a combination of endocytosis and paracellular way, while CS-PLGA-NPs mainly relied on the endocytosis way. PEG coating could shield the surface charge and enhance the hydrophilicity of PLGA nanoparticles, which leads mPEG-PLGA-NPs to possess higher anti-adhesion activity. As a result, mPEG-PLGA-NPs could penetrate the mucus layer rapidly and transport across Caco-2/HT29-MTX co-cultured cells.

Tacon K.C.B.,Federal University of Goais | Santos H.C.O.,Federal University of Goais | Parente L.M.L.,Federal University of Goais | da Cunha L.C.,Federal University of Goais | And 4 more authors.
Acta Cirurgica Brasileira | Year: 2011

Purpose: To evaluate the effect the healing activity of diode laser Indium Gallium Aluminum Phosphorus (InGaAlP) ë660nm on healing of surgical wounds in rats. Methods: Fifty-four female Wistar rats were used, divided into three groups (n=18) and subdivided into three subgroups (n=6) to be studied in 5, 10 and 15 th days after surgical procedures. The wound was induced in the dorsal-cervical using punch. The lesions were irradiated on alternate days with InGaAlP laser, the energy densities of 3J/cm 2 (L3) or 6J/cm 2 (L6). The control group received no irradiation. At 5, 10 and 15 th days after surgery the animals were euthanized and the repair area was removed and histological sections were stained with hematoxylin-eosin and picrossírius. We evaluated macroscopic and histological lesions in the times cited, as well as morphometric analysis of angiogenesis and collagen content. Results: The wound healing activity InGaAlP laser was evidenced by increased angiogenesis group L3 and L6 in relation to control group (CG) at the 5 th day (p=0.0001) and decreased polymorphonuclear infiltrate and hemorrhage (p=0.045 and p=0.07 respectively) in the groups L3 and L6 in relation to control group (GC). On the 10 and 15 th days was also observed in groups treated with laser L3 and L6 stimulation was pronounced fibroplasia (p=0.0003 and p=0.034 respectively) when compared with the control group (CG). Conclusion: The InGaAlP laser acted positively on the healing of skin wounds in rats.

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