Ali M.S.,University of Karachi |
Ali M.I.,University of Karachi |
Ahmed G.,University of Karachi |
Afza N.,Pharmaceutical and Research Center |
And 5 more authors.
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences | Year: 2012
In continuation of our search for new secondary metabolites from African Erythrina species, E. mildbraedii of Cameroon was investigated. As a result of this study, a new flavanone (mildbone, 1) and a new chalcone (mildbenone, 2) have been obtained and characterized by spectroscopic means. Both the compounds exhibited significant antioxidant and moderate lipoxygenase inhibitory activities. Compounds 1 and 2 showed potent antioxidant activity even stronger than the positive control. Among both the compounds, mildbone (1) was found to be potent in both the assays. © 2012 Verlag der Zeitschrift für Naturforschung, Tübingen.