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Ali M.S.,University of Karachi | Ali M.I.,University of Karachi | Ahmed G.,University of Karachi | Afza N.,Pharmaceutical and Research Center | And 5 more authors.
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences | Year: 2012

In continuation of our search for new secondary metabolites from African Erythrina species, E. mildbraedii of Cameroon was investigated. As a result of this study, a new flavanone (mildbone, 1) and a new chalcone (mildbenone, 2) have been obtained and characterized by spectroscopic means. Both the compounds exhibited significant antioxidant and moderate lipoxygenase inhibitory activities. Compounds 1 and 2 showed potent antioxidant activity even stronger than the positive control. Among both the compounds, mildbone (1) was found to be potent in both the assays. © 2012 Verlag der Zeitschrift für Naturforschung, Tübingen.

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