Pharma Patent Ltd
Pharma Patent Ltd
Speer G.,Semmelweis University |
Szamosujvari Jr. P.,Pharma Patent Ltd |
Dombai P.,Soldra International Ltd |
Csore K.,Pharma Patent Ltd |
And 8 more authors.
International Journal of Endocrinology | Year: 2013
Purpose. Adequate calcium intake is the basis of osteoporosis therapy - when this proves insufficient, even specific antiosteoporotic agents cannot exert their actions properly. Methods. Our representative survey analyzed the dietary intake and supplementation of calcium in 8033 Hungarian female and male (mean age: 68 years) (68.01 (CI95: 67.81-68.21)) patients with osteoporosis. Results. Mean intake from dietary sources was 665 ± 7.9 mg (68.01 (CI95: 67.81-68.21)) daily. A significant positive relationship could be detected between total dietary calcium intake and lumbar spine BMD (P = 0.045), whereas such correlation could not be demonstrated with femoral T -score. Milk consumption positively correlated with femur (P = 0.041), but not with lumbar BMD. The ingestion of one liter of milk daily increased the T -score by 0.133. Average intake from supplementation was 558 ± 6.2 mg (68.01 (CI95: 67.81-68.21)) daily. The cumulative dose of calcium - from both dietary intake and supplementation - was significantly associated with lumbar (r = 0.024, P = 0.049), but not with femur BMD (r = 0.021, P = 0.107). The currently recommended 1000-1500 mg total daily calcium intake was achieved in 34.5% of patients only. It was lower than recommended in 47.8% of the cases and substantially higher in 17.7% of subjects. Conclusions. We conclude that calcium intake in Hungarian osteoporotic patients is much lower than the current recommendation, while routinely applied calcium supplementation will result in inappropriately high calcium intake in numerous patients. © 2013 Gábor Speer et al.