Asnad,Jinnah Medical College Peshawar |
Nasir N.,Jinnah Medical College Peshawar |
Ali R.,Jinnah Medical College Peshawar |
Ishaq M.,Jinnah Medical College Peshawar
Medical Forum Monthly | Year: 2013
Introduction: The reduction of blood pressure lower than 130/85 mmHg provides additional benefits regarding both protection of organs and cardiovascular mortality. Amlodipine is a calcium channel-blocking agent with vasodilator activity and Ramipril is ACE inhibitor. Objective: the objective of this double-blind, comparative study evaluating the efficacy of Amlodpine 5mg and Ramipril 1.25mg in combination and as monotherapy in adult patient with essential hypertension. Study design. Double-blind, comparative study Place and Duration of Study: This study was conducted in the department of Biochemistry, University of Karachi from February 2011 to July 2011. Materials and Methods: This was multicenter randomized, double-blind, comparative study. Patients were selected from different hospitals of Orangi Town Karachi from February 2011 to July 2011 and study was conducted in the department of Biochemistry, University of Karachi. Patients were randomized to receive Amlodopine (5mg) once daily Ramipril (1.25 mg) once daily for 8 weeks. The analysis of antihypertensive efficacy and biochemical effects of a therapeutic regimen in the long term becomes important. In study patents were randomized to receive amlodipine 5mg once daily, Ramipril 1.25 mg once daily, the combination of amlodipine 5mg with Ramipril 1.25 mg once daily. Results: In the patients treated with combination of Amlodipine 5mg and Ramipril 1.25mg tablets blood pressure reduction was significantly lower, reaching values of 130.4 ± 10.2 / 84.1 ± 7.4 mmHg by the end of eight weeks of treatment Conclusion: The results of this study demonstrated that the combination of amlodipine 5mg with Ramipril 1.25 mg once daily has a high antihypertensive efficacy and showed synergetic effect.
Karim F.,Jinnah Medical College Peshawar |
Mehsar A.L.,Jinnah Medical College Peshawar |
Bux M.,Jinnah Medical College Peshawar |
Ishaq M.,Jinnah Medical College Peshawar |
Ahmed I.,Jinnah Medical College Peshawar
Medical Forum Monthly | Year: 2014
Objective: The present study was design to know the biochemical Risk Factors of the upper urinary Tract Stone Disease in the Peoples of Peshawar and Charsadda District. Study Design: Observational Study Place and Duration of Study: This study was carried out at District Head Quarter Teaching Hospital Charsadda & Naseerullah Khan Babar Memorial Teaching Hospital Kohat Road Peshawar from 12th August 2012 to 11th August 2013. Materials and Methods: One hundred subjects who were suffering from upper urinary tract stone disease were included in the study. The evidence of stone in the renal and history of spontaneous passage of stones in the urine were determined regarding Microscopic Examination. Results: The age range of our subject was between 01-60 years. The mean age ± S.D of age of stone former for men was 34.6 ± 8.6 years and for female 30.8 ± 6.7 in N.S.F. Family history of stone disease was found in (16%) of patients. 4% in maternal side and 12% paternal. Conclusion: The Serum Phosphate level was higher in S.F than N.S.F and is a risk factor for Upper Urinary Tract Stone Disease in Peshawar and Charsadda.
Ahmad M.,Jinnah Medical College Peshawar |
Fida R.,Jinnah Medical College Peshawar |
Khattak N.N.,Jinnah Medical College Peshawar |
Akhund I.A.,Jinnah Medical College Peshawar
Medical Forum Monthly | Year: 2013
Study design: Retrospective as well as prospective study. Place and Duration of Study: This study was carried out in the out patients department of DHQ teaching hospital charsadda for the period of nine months between 2010 and 2011. Patients and Methods: Total number of children/infants was fifty. All suspected patients were carefully examined and divided into two groups. Statistically analysis was done by student's "t" table. Results: When results were summed up and test parameters were separated it was seen that the success rate with sample massaging and use of topical antibiotic was 90% at the end of nine months. Five infants improved with single probing. Conclusion: Infantile epiphora due to nasolacrimal duct obstruction generally cured with auto canalization/massaging with topical antibiotics at the age of 5 months. The 2nd thing in this study that we can use topical anesthetic agent instead of exposing the infant to the hazard and the complication of general anesthesia.