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Washington, DC, United States

Patent
Perseus Inc. and Fujita Health University Hospital | Date: 2013-05-10

To provide a method for detecting cellular DNA damage by specifically recognizing molecules responsive to DNA strand breaks. A method for detecting DNA damage in cells, which comprises administering in vivo, to cells, an antibody against a cell membrane surface antigen that is expressed in cells undergoing DNA strand breaks to a greater extent than in cells not undergoing DNA strand breaks in an environment that causes DNA damage, and analyzing the expression status of the cell membrane surface antigen.


Patent
Perseus Inc. | Date: 2014-12-22

Provided is a method for diagnosing cancer by detecting a novel cancer marker. Cancer can be diagnosed by detecting soluble glypican 3 in a test sample.


A method for transmitting an energy beam from a group of elements of an external phased array energy projector for a medical ablation treatment. The method comprises transmitting first energy pulses from a subset of elements of the group, measuring signal parameters of first energy signals from reception of first energy pulses by energy sensors, and calculating for the group energy transmission parameters. The method further comprises transmitting second energy pulses by other elements, measuring signal parameters of second energy signals based on a reception the pulses by energy sensors, and calculating for the group a second set of energy transmission parameters. The method further comprises calculating transmission instructions for transmitting a phased array energy beam from the group by combining first and second energy transmission parameters. The method transmits an energy beam based on the transmission instructions.


Patent
Perseus Inc. | Date: 2012-09-02

A method of modulating tissue of an internal organ in vivo is disclosed. The method comprises: fixating the tissue on a shaped device so as to shape the tissue generally according to a shape of the device; and focusing radiation on the fixated tissue using a radiation-emitting system so as to modulate the tissue, wherein the radiation-emitting system is non-local with respect to the shaped device.


It is an object of the present invention to provide an anti-cadherin antibody having high antibody-dependent cellular cytotoxicity. The present invention provides an anti-cadherin antibody, which recognizes any one of an upstream region of EC1, a cadherin domain 4 (EC4) and a cadherin domain 5 (EC5), wherein an antibody-dependent cellular cytotoxicity at an antibody concentration of 1 g/mL is 30% or more.

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