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Perm’, Russia

Gein V.L.,Perm Pharmaceutical Academy | Zamaraeva T.M.,Perm Pharmaceutical Academy | Slepukhin P.A.,Russian Academy of Sciences
Tetrahedron Letters | Year: 2014

Ethyl 6-amino-4-aryl-5-cyano-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylates were synthesized via a four-component reaction of the sodium salt of diethyloxaloacetate, an aromatic aldehyde, hydrazine hydrate, and malononitrile. The products were obtained in moderate to high yields. © 2014 Elsevier Ltd. All rights reserved.

Kon'shin M.E.,Perm Pharmaceutical Academy | Efremov A.L.,Perm Pharmaceutical Academy | Vakhrin M.I.,Perm Pharmaceutical Academy | Gorbunov A.A.,RAS Institute of Technical Chemistry
Russian Journal of Organic Chemistry | Year: 2012

Reactions of 2-(phenylamino)benzoic and 2-(phenylamino)- and 2-methyl-6-phenylpyridine-3- carboxylic acid hydrazides with succinic anhydride in organic solvents at room temperature gave the corresponding 4-(2-aroylhydrazinyl)-4-oxobutanoic acids. The reactions in boiling acetic acid afforded N-(2,5-dioxopyrrolidin-1-yl)benzamide or N-(2,5-dioxopyrrolidin-1-yl) pyridine-3-carboxamide. © Pleiades Publishing, Ltd., 2012.

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