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Salem, India

Periyar University is a university located in Salem, Tamil Nadu, India. It was established by the Government of Tamil Nadu in 1997. The university is named after a social reformer Thanthai Periyar. The University Grants Commissions, New Delhi bestowed the 2f status in 1998 and 12 status in 2005 to the university. The university is accredited with NAAC. Wikipedia.

Krishnaveni M.,Periyar University
Asian Journal of Pharmaceutical and Clinical Research

Objective: The main objective of this study is to assess the secondary metabolites and antioxidant activities of Terminalia catappa nut as it is not a commercialized nut. Materials and Methods: The secondary metabolites and antioxidant activities were experimented by adopting recommended standard procedures using aqueous extract of T. catappa nut powder 25, 50, 75, 100 mg. Results: The total phenolics content was higher on comparison with flavonoid content. Similarly, among the antioxidant activities, nitric oxide scavenging (257.33±2.30 mg/g) as well as reducing power activity (142.66±6.11 mg/g) was higher compared with total antioxidant (82.66±6.11 mg/g) and metal chelating activity (64.66±2.30 mg/g). Conclusion: The results obtained shows that it contained phenolics and flavonoid, which in turn induces antioxidant activities. Hence, this might act as a potential antioxidant, and needs further characterization and purification. © 2014 Asian Journal of Pharmaceutical and Clinical Research. All rights reserved. Source

Buvaneswari N.,Periyar University | Kannan C.,Manonmaniam Sundaranar University
Journal of Hazardous Materials

Effluents releasing from dyeing industries directly affect the soil, water, plant and human life. Among these dyes, plant poisoning, soil polluting and water polluting nature of organic dyes are not yet identified. The plant poisoning and non-poisoning organic dyes are identified through adsorption mechanism of cationic malachite green (MG) and anionic methyl orange (MO) on brinjal plant root powder (cellulose). The positive ΔHo (44kJmol-1) of MG higher than 40kJmol-1 confirmed the adsorption of MG on cellulose is chemisorption and the negative ΔHo (-11kJmol-1) less than 40kJmol-1 showed that the adsorption of MO on cellulose is physisorption. The ΔGo values for the adsorption of MG and MO on BPR are not much increased with increase of temperature which indicated that the adsorption is independent of the temperature. The entropy change for the adsorption of MG and MO has proved that the MG (+ΔSo) has less disorder at the adsorption interface and MO (-ΔSo) has the high disorder at the adsorption interface. The recovery of both dyes has been studied in water at 80 °C on BPR surface and observed that the MO recovery is 95% and MG is 10%. The poor desorption of MG is due to the strong chemisorption on BPR (cellulose) surface proves its plant poisoning nature. The high recovery of MO due to physisorption mechanism proves that MO is not poisoning the plant. © 2011 Elsevier B.V. Source

Raja R.,Periyar University | Samidurai R.,Thiruvalluvar University
Journal of the Franklin Institute

This paper is concerned with the stability analysis problem for a class of delayed stochastic recurrent neural networks with both discrete and distributed time-varying delays. By constructing a suitable Lyapunov-Krasovskii functional, a linear matrix inequality (LMI) approach is developed to establish sufficient conditions to ensure the global, robust asymptotic stability for the addressed system in the mean square. The conditions obtained here are expressed in terms of LMIs whose feasibility can be checked easily by MATLAB LMI Control toolbox. In addition, two numerical examples with comparative results are given to justify the obtained stability results. © 2012 The Franklin Institute. All rights reserved. Source

Chitosan (CS)-polylacticacid (PLA)-polyethylene glycol (PEG)-gelatin (G) nanoparticles, a novel drug vehicle for the controlled release of an antitubercluosis drug, rifampicin (RIF) was developed and its chemical and biochemical activities were studied by various standard methods. The designed carriers CS, PEG and G nanoparticles were prepared by emulsion solvent evaporation technique, and then used for entrapping RIF. Linking was confirmed by FTIR spectroscopy. The surface morphology of the nanoparticles was studied using scanning electron microscope and polarizing microscope. The influence of process variables, on particle size, zeta potential and matrix entrapment of RIF was studied. The encapsulation and loading capacity were evaluated, and an in vitro release of RIF was assessed using the dialysis method. The effect of nanoencapsulation of RIF on the antibacterial activity of RIF against Mycobacterium strains was evaluated. The preliminary results clearly suggested that the cross linked CS-PLA-PEG-G matrix may be a potential polymeric carrier for controlled delivery of RIF. © 2013 Published by Elsevier Ltd. Source

Thiyagarajan M.,Periyar University | Venkatachalam P.,Periyar University
Industrial Crops and Products

Stevia rebaudiana is a valuable medicinal plant species and it is being used for the treatment of diabetes. Currently, there is a high demand for raw material of this medicinal herb due to ever increasing diabetes disorder among the population. In order to meet the increased demand an efficient in vitro propagation of S. rebaudiana was established. Nodal explants collected from the field were cultured on MS basal medium fortified with different concentrations of BAP (0.5-3.0. mg/l) and KIN (0.5-3.0. mg/l) individually for shoot bud induction. In vitro derived nodal buds were cultured on MS medium supplemented with different concentrations (0.5-3.0. mg/l) of BAP and KIN for multiple shoot bud regeneration. In the second experiment, in vitro derived buds were placed on MS medium supplemented with different concentrations of BAP (0.5-3.0. mg/l) in combination with 0.5. mg/l IAA or IBA or NAA for shoot bud multiplication. The highest frequency (94.50%) of multiple shoot regeneration with maximum number of shoots (15.69 shoots/explant) was noticed on MS medium supplemented with 1.0. mg/l BAP. For large scale plant production, in vitro derived nodal bud explants were cultured on MS medium fortified with 1.0. mg/l BAP, in which about 123 shoots/explant were obtained after three subcultures on the same media composition. Elongated shoots (>2. cm) dissected out from the in vitro proliferated shoot clumps were cultured on half-strength MS medium containing different concentrations of NAA (0.1-0.5. mg/l) and/or MS medium fortified with various concentrations (0.5-2.0. mg/l) of auxins (NAA, IAA and IBA) for root induction. Highest frequency of rooting (96%) was noticed on half-strength MS medium augmented with 0.4. mg/l NAA. The rooted plantlets were successfully transferred into plastic cups containing sand and soil in the ratio of 1:2 and subsequently established in the greenhouse. The present in vitro propagation protocol would facilitate an alternative method for rapid and large-scale production of this important antidiabetic medicinal plant. © 2011 Elsevier B.V. Source

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