Time filter

Source Type

Patent
Stealth Peptides International Inc. | Date: 2016-05-26

This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof, wherein the peptide is D-Arg-2 6-Dmt-Lys-Phe-NH2 (SS-31).


Patent
Stealth Peptides International Inc. | Date: 2017-05-24

The disclosure relates to methods for treating a subject suffering from hyperalgesia caused by drug-induced neuropathy by administering to the subject an effective amount of an aromatic-cationic peptide. The disclosure also relates to methods for protecting a subject from hyperalgesia caused by drug-induced neuropathy by administering an effective amount of an aromatic-cationic peptide to a subject at risk for developing the condition.


Patent
Stealth Peptides International Inc. | Date: 2015-08-26

This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof, wherein the peptide is D-Arg-2 6-Dmt-Lys-Phe-NH2 (SS-31).


Patent
Stealth Peptides International Inc. | Date: 2015-09-09

The invention provides methods of treating an obstructive coronary artery disease in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof, and performing a coronary artery bypass graft procedure on the subject.


Patent
Stealth Peptides International Inc. | Date: 2016-03-02

The present invention provides methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject, comprising administering to the subject a therapeutically effective amount of an aromatic-cationic peptide represented by the formula D-Arg-2,6-Dmt-Lys-Phe-NH2 (SS-31) or Phe-D-Arg-Phe-Lys-NH2 (SS-20). The present invention provides methods of preventing or treating ophthalmic diseases or conditions such as diabetic retinopathy, cataracts, retinitis pigmentosa, glaucoma, macular degeneration, choroidal neovascularization, retinal degeneration, and oxygen-induced retinopathy.


Patent
Stealth Peptides International Inc. | Date: 2016-07-06

The invention provides compositions and methods for preventing or treating an ischemia-reperfusion injury, such as occurs during acute myocardial infarction and organ transplant in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide or a pharmaceutically acceptable salt thereof, and one or more additional active agents such as cyclosporine.


Patent
Stealth Peptides International Inc. | Date: 2016-11-09

This invention provides methods of preventing or treating cardiac ischemiareperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof, wherein the peptide is D-Arg-2 6-Dmt-Lys-Phe-NH2 (SS-31).


Patent
Stealth Peptides International Inc. | Date: 2016-10-12

The disclosure provides methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject. The methods comprise administering an effective amount of an aromatic-cationic peptide to subjects in need thereof. More specifically, the disclosure provides a composition for preventing, treating, or ameliorating the symptoms of diabetic macular edema in a mammalian subject in need thereof, comprising: a therapeutically effective amount of a peptide D-Arg- 26-Dmt-Lys-Phe-NH2 or a pharmaceutically acceptable salt thereof.


Patent
Stealth Peptides International Inc. | Date: 2016-12-07

The invention provides methods of treating an obstructive coronary artery disease in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof, and performing a coronary artery bypass graft procedure on the subject.


Patent
Stealth Peptides International Inc. | Date: 2016-04-20

The disclosure provides compositions and methods relating to aromatic-cationic peptides. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof. For example, the peptides may be administered to subjects in need of a mitochondrial-targeted antioxidant.

Loading Stealth Peptides International Inc. collaborators
Loading Stealth Peptides International Inc. collaborators