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Li J.,Peoples Hospital of Zhengzhou
Pakistan journal of pharmaceutical sciences | Year: 2015

This study was to discuss the clinical diagnosis and treatment features of severe pulmonary infections after renal transplantation, in order to improve the cure rate. Retrospective research was applied to analyze the 52 cases of patients with serve pulmonary infection after renal transplantation in the department of organ transplantation in People's Hospital of Zhengzhou from July, 2008 to December, 2013. The pathogens which caused the pulmonary infection after renal transplantation were bacteria, virus, fungi, mycobacterium tuberculosis, combined infection and unknown pathogens, and the rate were respectively 28.85%, 15.38%, 7.69%, 3.85%, 21.15% and 23.08%. In the 52 cases, there were 41 cases of patients successfully survived, which was 78.85% and 11 cases died, which was 21.15%. The mortality rate of combined infection and unknown pathogens infection was significantly higher than that of single pathogen infection. Pulmonary infection after renal transplantation was of rapid deteriorated progress and high mortality rate. It was significant for patients to receive the comprehensive and integrated treatment.

Zhang J.-L.,Peoples Hospital of Zhengzhou
Applied Mechanics and Materials | Year: 2014

Medical equipment maintenance and use of personnel, is crucial. Used properly and rational division of engineering and technical personnel, strict management, to train engineering technical personnel with professional spirit, all-round for clinical medical services; To strengthen the training of equipment use of personnel, highlight the preventive maintenance and maximize or prolonged trouble-free of medical instrument equipment, ensure the effective operation of the clinical diagnosis and treatment work. © (2014) Trans Tech Publications, Switzerland.

Jiang H.Y.,Peoples Hospital of Zhengzhou
Applied Mechanics and Materials | Year: 2014

In this paper, the advantages and disadvantages of the existing ultrasonic image management system are analyzed, and also a multi-functional color Doppler ultrasound image-text management system is researched and developed in combination with the experience of color Doppler ultrasound doctors. With this system, the related operations such as color Doppler ultrasound images acquisition, processing, preservation, and medical records are implemented. In the design of the system, a professional acquisition card is used for implementing the acquisition of ordinary video signals. In the meantime, DICOM interface is designed using DICOM3.0 protocol for implementing multi-mode acquisition. © (2014) Trans Tech Publications, Switzerland.

Liu X.-A.,Peoples Hospital of Zhengzhou
International Journal of Ophthalmology | Year: 2012

AIM: To observe the effects of salvianolic acid B (SalB) on in vitro growth inhibition and apoptosis induction of retinoblastom a HXO-RB44 cells. METHODS: The effects of SalB on the HXO-RB44 cells proliferation in vitro were observ ed by MTT colorimetric method. The morphological changes of apoptosis before and after the treatm ent of SalB were observ ed by Hoechst 33258 fluorescent staining m ethod. Apoptosis rate and cell cycle changes of HXO-RB44 cells were detected by flow cytometer at 48 hours after treated by SalB. The expression changes of Caspase-3 protein in HXO-RB44 cells w ere detected by Western Blot. RESULTS: SalB significantly inhibited the growth of HXO-RB44 cells, while the inhibition was in a concentration-and tim e-dependent m anner. The results of fluorescent staining m ethod indicated that HXO-RB44 cells show ed significant phenom enon of apoptosis including kary orrhexis, fragm entation and the form ation of apoptotic bodies, etc. after 24, 48 and 72 hours co-culturing of SalB and HXO-RB44 cells. The results of flow cytom eter show ed that the apoptosis rate and the proportion of cells in Sphase were gradually increased at 48 hours and 72 hours after treated by different concentrations of SalB. Western Blot strip showed that the expression of Caspase-3 protein in HXO-RB44 cells was gradually increased with the increase of the concentration of SalB. CONCLUSION: SalB can significantly affect on HXO-RB44 cells growth inhibition and apoptosis induction which may be achieved through the up-regulation of Caspase-3 expression and the induction of cell cy cle arrest. Copyright International Journal of Ophthalmology Press.

Zhang C.,Peoples Hospital of Zhengzhou
Pakistan journal of pharmaceutical sciences | Year: 2015

This study discussed about the influence of local application of glaucoma medications -- travoprost eye drops to patients' tear film function. We selected 24 patients, 45 eyes with primary open-angle glaucoma or intraocular hypertension. All of the patients topically used the travoprost eye drops for one time every night. After and before the pharmacy, we proceeded 1, 2, 3 mo lines symptom score and Schirmer's test (St), corneal fluorescein staining (FL), breakup time of tear film (BUT). Average value of symptom score and FL of all the patients before pharmacy were 1.32 ± 1. 55, 0.42 ± 0.68, and 1, 2, 3mo after pharmacy were respectively 2.68 ± 1.59, 0.96 ± 0.81; 4.97 ± 1.62, 1.46 ± 0.62; 6.21 ± 1.33, 1.88 ± 0.44. Symptom score and FL of 1, 2, 3 mo patients after pharmacy were all prominent higher than it before pharmacy (P=0.00), and it gradually increased. The average value of patients symptom BUT and St before pharmacy were (7.71 ± 0.87s), (8.32 ± 2.63mm /5min) and 1, 2, 3 mo after pharmacy were respectively (6.93 ± 1.17s), (7.69 ± 3. 33mm /5min); (5.48 ± 1.29s), (6.79 ± 2.94mm /5min); (4.33 ± 1.83s), (5.98 ± 3.11mm/5min). BUT and St value after pharmacy were prominent all lower than the level before pharmacy (P=0.00). And it gradually reduced. Short-term use of travoprost eye drops would aggravate the corneal irritation of patients, and decrease the tear film stability and tear secretion.

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