PDM Dental College and Research Institute

Bahādurgarh, India

PDM Dental College and Research Institute

Bahādurgarh, India
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Pandey R.,MM Institute of Medical science and Research | Singh M.,PDM Dental College and Research Institute | Singhal U.,PDM Dental College and Research Institute | Gupta K.B.,Pt. B. D. Sharma University of Health Sciences | Aggarwal S.K.,P.A. College
Journal of Clinical and Diagnostic Research | Year: 2013

The understanding of the pathobiology of Chronic Obstructive Pulmonary Disease (COPD) has undergone a major change in the past three decades. The classical 'protease-antiprotease' hypothesis still holds true, nevertheless, the sequence of the biochemical events which lead to the protease/antiprotease imbalance have been unraveled. For instance, tobacco smoke, a primary risk factor for COPD, contains a plethora of reactive Oxygen/ Nitrogen Species (ROS/RNS) that serve to initiate the oxidant/ antioxidant imbalance in the respiratory tract of chronic smokers, a phenomenon that is amplified if certain other risk factors co-exist (e.g. a genetic deficiency of the major antiproteases, a suboptimal antioxidant defense system, airway hyper responsiveness etc.). The infammatory response that ensues as a result of the initial occult exogenous oxidative/ nitrosative stress becomes a secondary endogenous source of ROS/RNS. This perpetuates the ongoing lung damage, even though the primary insult may no longer be present (abstinence). Depletion of the pulmonary antioxidants, damage to the local antiprotease protective screen, a decreased immune response, hypersecretion of mucus, superadded infections, oxygen therapy-induced oxidant production, etc. are some of the critical factors which account for the oxidative/ nitrosative stress-mediated pulmonary as well as extrapulmonary features of COPD. In the light of the recent developments, remarkable efforts are being made, either to develop novel therapeutic strategies or to improve the existing ones, which are aimed at treating different aspects of the disease. Thus, it is reasonable to recommend antioxidants as a useful adjunct to the more conventional treatment options, keeping in view the 'oxidant/antioxidant' hypothesis as a unifying theme for the 'protease/antiprotease' theory of COPD.


Kumar A.,PDM Dental college and Research Institute | Virdi M.,PDM Dental college and Research Institute
Internet Journal of Epidemiology | Year: 2010

Objectives: Assess the oral health status & treatment needs, among rural population of ambala. Study participants & methods: This was a cross-sectional descriptive study conducted in 12 villages of ambala district, Haryana, India. A total of 1250 subjects aged 20-74 years, were examined using modified WHO format 1997 & interviewed using structured questionnaire. Statistical Analysis: Chi-square and ANOVA were used. Results: 31.5% subjects were uneducated, 55.2% subjects were unemployed 72.6% (896) belonged to poor class. A total of 32828 teeth were examined among which 10% were decayed. The mean DMFT was 5.2. Most of the subjects had CPITN score 2.35.2% of subjects needed prosthetic status in maxillary arch & 45.3% in mandibulararch. Dental caries was significantly associated with gender, education, socioeconomic status & brushing frequency. Periodontal disease was significantly related to frequency of brushing & age.Conclusion: Oral health status was not satisfactory. Nearly 90% of subjects needed one or other form of dental treatment.


Tandon A.,PDM Dental College and Research Institute | Agarwal V.,ITS Dental College Hospital and Research Institute | Arora V.,University of Lucknow
Journal of Oral Biology and Craniofacial Research | Year: 2015

Objectives: The study was conducted to check the reliability of India-specific regression formula for age estimation of population in and around Bahadurgarh, Haryana (India). Materials and methods: The study was conducted using digital orthopantomograms (OPGs) of 464 subjects (253 males and 211 females). Chronologic age (CA) was derived from that mentioned on the OPG. Each tooth in the left mandibular segment was scored using Demirjian's scoring and age was calculated using the regression formulas derived by Acharya. The difference of the chronologic and estimated age was used to check the reliability of India-specific regression formula. Results: The mean estimated age was found to be significantly higher as compared to CA for overall as well as both the genders independently (p < 0.001). Difference (in ±) between estimated and CA ranged from 0 to 4.2 years. Mean difference in age was 0.85 ± 0.73 years for males and 0.87 ± 0.76 years for females. Conclusion: The published India-specific regression formula does not have reliability in the population of Bahadurgarh, Haryana and hence cannot be universally applied. © 2015 Craniofacial Research Foundation.


PubMed | Lady Hardinge Medical College, Himachal Dental College, Postgraduate Institute of Medical science and Research and PDM Dental College and Research Institute
Type: Journal Article | Journal: Oral and maxillofacial surgery | Year: 2016

Reports of post herpetic maxillofacial complications have been very rarely documented in the literature that includes periapical lesions, calcified and devitalized pulps, resorption of roots, osteonecrosis, and spontaneous exfoliation of teeth. The atypical feature of the case of concern to the dental surgeon is the rare complication of spontaneous tooth exfoliation following herpes zoster.This case reports a male patient of age 47years who reported to the Department of Periodontology with the chief complaint of mobility in the left upper central incisor. Patient history revealed herpes zoster infection that began 11days earlier along with underlying diabetes mellitus condition. We hereby report a known diabetic patient with history of herpes zoster infection who presented with rare complication of spontaneous tooth exfoliation involving the maxillary division of the trigeminal nerve.Limited number of cases has been reported in the literature regarding spontaneous teeth exfoliation secondary to herpes zoster. The exact pathogenesis regarding the spontaneous exfoliation of teeth in herpes zoster patient is still controversial. Thus, an oral health care provider should be aware of this rare complication while managing a case of tooth mobility with the previous history of herpes zoster of trigeminal nerve.


Singh M.,NIMS University | Gupta S.,Government Medical College | Singhal U.,PDM Dental College and Research Institute | Pandey R.,M M Institute Of Medical Science And Research | Aggarwal S.K.,P.A. College
Journal of Clinical and Diagnostic Research | Year: 2013

AIM: The present study was conducted to assess the activity of Gamma Glutamyl Transferase (GGT) and its association with oxidative stress in alcoholics. Method: Sixty male alcoholics with a history of alcohol abuse for more than five years were the subjects of this study. Twenty healthy male volunteers who matched in age and the socio- economic status, served as the control subjects. Results: GGT, reduced glutathione (GSH, a key intra-cellular antioxidant) and malondialdehyde (MDA, a marker of the oxidative stress) were assayed in the plasma of the two groups, and the results were statistically analyzed. The activity of the plasma GGT, known as a marker of Alcoholic Liver Disease (ALD); was significantly higher in the alcoholics as compared to that in the healthy controls. Conclusion: There was a significant positive correlation between the enzyme activity and the plasma levels of MDA and this indicated that there was an increased release of this enzyme with enhanced oxidative damage, due to the generation of oxygen free radicals in the study group. There was a significantly increased level of MDA and a decrease in the level of GSH in the alcoholics as compared to those in the controls. Significant negative correlations between GGT and GSH, and between MDA and GSH were observed. The present study demonstrates that alcoholics have a compromised antioxidant defense system.


Singh M.,PDM Dental College and Research Institute | Aggarwal H.K.,PGIMS | Aggarwal S.K.,PDM Dental College and Research Institute
Journal of Clinical and Diagnostic Research | Year: 2012

Objectives: The present study was conducted to assess the activity of glutathione -S-transferase (GST) and its relationship with total thiols (T-SH) in patients with alcohol liver disease (ALD). Methods: Twenty male chronic alcoholics who had a history of alcohol abuse for more than five years were included in the present study and twenty healthy male volunteers who matched in age and socio-economic status, served as the controls. The plasma GST activity and the T-SH concentration were assayed. Results: The activity of plasma GST was significantly higher in the chronic alcoholics as compared to that in the healthy controls. There was a significant decrease in the T-SH concentration and an increase in the aminotransferase (AST and ALT) and alkaline phosphatase (ALP) activities. Moreover, there was a significant negative correlation of the GST activity with the T-SH concentration (r = 0.45; p< 0.001). Conclusions: The findings of the present study indicated that GST was a sensitive marker in the diagnosis of ALD. A significantly low concentration of T-SH was observed in the alcoholics as compared to that in the controls. Both these parameters (plasma GST activity and total thiols) showed a significantly negative correlation, indicating that there was an increase in the activity of GST with a decrease in the concentration of T-SH.


Yadav S.,PDM Dental College and Research Institute
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology | Year: 2012

Necrotizing fasciitis (NF) is defined as rapidly progressive necrosis of subcutaneous fat and fascia. It is a rare but life-threatening infection characterized by a progressive, usually rapid, necrotizing process of the subcutaneous tissues and fascial planes. The condition is commonly described in the extremities, abdominal wall, and perineum but rarely seen in the head and neck. The diagnosis of NF depends mainly on clinical features, which are not always observable, so that the disease is often diagnosed late in its course, resulting in high mortality. Broad-spectrum antibiotics, aggressive surgical treatment and supportive therapy are the most widely accepted modalities of successful treatment. We describe a case of necrotizing fasciitis of the head and neck, arising from odontogenic origin. © 2012 Elsevier, Inc. All rights reserved.


Neeti B.,PDM Dental College and Research Institute
Internet Journal of Pediatrics and Neonatology | Year: 2011

Dentinogenesis Imperfecta (DGI) is a genetic disorder of tooth development inherited in an autosomal, dominant way, characterized by the presence of translucent or opalescent dentin, resulting in discoloration (amber-like, bluish grey color) of the teeth. It is a mesodermal defect wherein the dental papilla of either or both the primary and secondary dentition is abnormal. This paper describes the dental findings in a family where the father (33 year old) and the son (3 year old) both showed the characteristic dental features of DGI I. © internet Scientific Publications, LLC.


Virdi M.,PDM Dental College and Research Institute | Bajaj N.,PDM Dental College and Research Institute | Kumar A.,PDM Dental College and Research Institute
Internet Journal of Epidemiology | Year: 2010

Objectives: Despite advances in the oral health of children in recent decades, early childhood caries (ECC) continues to pose a serious threat. The purpose of this study was to determine prevalence of severe ECC in children less than five years of age over the duration of two years.Study participants and methods: This retrospective study included 709 children attending the department of pediatric dentistry at the PDM Dental College and Research Institute, Bahadurgarh, Haryana between 2008 and 2010. The sample size constituted of 394 boys and 315 girls aged between 1 and 5 years (mean age = 4.31 ± 91 years). Severe ECC was determined as per the guidelines of American Academy of Pediatric Dentistry (AAPD). Statistical Analysis: Chi-square and ANOVA were used. Results: The prevalence S-ECC was 42.03%. The overall mean dmfs was 5.08 +/- 5.56. The statistical analysis highlighted insignificant relation between prevalence of S-ECC with respect to gender and age, though in general, Ip S-ECC (Girls) was higher than Ip S-ECC (boys). With respect to age distribution, higher prevalence of S-ECC was noted in the age group of 3 and 5 years. Conclusion:The increase in the percentage of children seeking treatment at the age of 5 years and above indicated less awareness among parents on the subject. Sustained efforts are still needed in order to find more appropriate methods to educate parents regarding the prevention of this caries pattern. Oral health promotion programs should be extended to all health care facilities where children from all socio-economic levels are visiting from infancy on.


PubMed | PDM Dental College and Research Institute
Type: Journal Article | Journal: International journal of clinical pediatric dentistry | Year: 2016

Traumatic injuries to primary dentition may interfere with the development of permanent dentition. Among the many malformations, dilaceration is particularly important to the clinician. Management of dilacerated maxillary central incisor requires a multidisciplinary approach. The main purpose of this review is to present the etiological factors, the mechanism, clinical features, radiographic features and treatment of dilaceration of the maxillary central incisors. How to cite this article: Walia PS, Rohilla AK, Choudhary S, Kaur R. Review of Dilaceration of Maxillary Central Incisor: A Multidisciplinary Challenge. Int J Clin Pediatr Dent 2016;9(1):90-98.

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