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Bhopal, India

Bhowate S.,PCMS and RC
Indian Journal of Forensic Medicine and Toxicology

Instances of cruelty to women have been brought to the spotlight like never before in the recent past. But what goes mostly unnoticed is the plight of a section of men folk, who undergo mental torture and lose the best years of their life and even their careers fighting false allegations charged by their spouses. With an approximately 60,000 such accusations per year, about 2,00,000 people are directly affected by these false accusations. The number of such cases has increased by about 100% in the last 10 year and by more than 15% in just the last two years. Unless urgent amendments are made to prevent the misuse of these laws, credibility of women will be lost. In addition to lost credibility, an overload of false cases will worsen the delays in the judicial process and deny timely justice to women who are genuinely aggrieved. © 2015, Indian Journal of Forensic Medicine and Toxicology. All rights reserved. Source

Khadanga S.,AIIMS Bhopal | Dugar D.,Hitech Medical College and Hospital | Khurana U.,PCMS and RC | Satapathy S.P.,Aditya Care Hospital
BMJ Case Reports

A middle-aged woman presented in shock with bleeding per rectum for 2 days without any significant past medical or surgical illness. Abdominal sonography, oesophagogastroduodenoscopy and sigmoidocolonoscopy were unremarkable. Despite 6 units of blood transfusion, 3000 mL of plasma expanders and ionotropes, the arterial pressure gradually decreased. We had no choice but to undergo life-threatening yet possibly life saving laparotomy. We found a 1×1 cm ileal bleeding mucosal polyp about 20 cm away from the ileocaecal junction. We resected and anastomosed end to end. Perioperatively, the patient was transfused with another 4 units of blood product. Immunohistopathology revealed a large number of CD34 positive spindle cells and eosinophils with extensive thick-walled capillaries compatible with inflammatory fibroid polyp. This case of Vanek's tumour is reported for its atypical site, which presented as massive obscure gastrointestinal haemorrhage without any prior warning signs. Source

Gupta S.K.,PCMS and RC | Purty A.J.,PlMS | Singh Z.,PlMS | Bazroy J.,PlMS | Cherian J.,PlMS
Indian Journal of Community Health

Research question: What is the knowledge, attitude and practice towards HIVIAIDS in a general population? Objectives: (1) To assess the knowledge about mode of transmission, treatment and prevention of HIVIAIDS. (2) To study the socio demographic pattern, myths and misconceptions. Study design: Community based cross sectional study. Setting: Chunampett Village, Tamilnadu. Duration: March to May 2007. Participants: 845 both males and females above the age of 18 years interviewed at home. Results: Population surveyed was 845, comprising of 482 (57.04%) males and 363 (42.96%) females. Most of them were Hindus (96.10%). Main occupation was agriculture (39.41%) among males and house wives (33.73%) among females. 40.35% respondents belonged to low socioeconomic status. Illiteracy rate was high especially among females (43%).Source of information about HIVIAIDS was mass media in about 85% of the population. Majority of individuals (58.5%) were not aware that the disease was contagious. An overwhelming majority (98.59%) were aware about the mode of transmission of HIVIAIDS through sexual route. However about 20% had myths regarding transmission of disease. 65% knew that HIVIAIDS is preventable, yet only 4% used condoms. A vast majority (60-65%) were not aware that treatment and PEP were available free of cost in government hospitals. A majority of about 54.22% were of the opinion that the diagnosis of HIVIAIDS should not be kept confidential. Conclusion: The awareness about HlV /AIDS is high among the study population but the implementation of preventive measures is low. The knowledge about availability of prophylactic and therapeutic measures against HIV /AIDS in Govt. hospitals is also low. Source

Jiwane R.,PCMS and RC | Deshpande V.K.,Jawaharlal Nehru Medical College | Biswas D.A.,Jawaharlal Nehru Medical College
Journal of Datta Meghe Institute of Medical Sciences University

The present study was undertaken to compare the effect of drugs on the total functional sperm count (TFSC) and sperm motility index (SMI). TFSC provides the integrated value of morphologies and sperms with useful motility. SMI measures the number of motile sperms and multiplies them with their forward speed. Therefore these parameters grade the overall sperm quality objectively. Eighty subjects were selected and randomly given the treatment, out of which 40 patients received treatments with indigenous drug Capsule Addyzoa & labeled as Group I and another 40 patients received Allopathic drug Tab clomiphene citrate labeled as Group II and the effects of these drugs on TFSC & SMI were evaluated after 3 and 6 months. Improvement in TFSC of sperm was better with group I than group II (p<0.01) at 3 months. But the difference was not statistically significant at 6 months (p > 0.05) and the improvement in SMI score is better with group I than with group II at 6 months (p < 0.05). Conclusion: Treatment with Cap Addyzoa improves TFSC AND SMI better than treatment with Tab clomiphene citrate. Source

Mehta S.,Eisai Pharmaceuticals India Private Ltd | Chandersekhar K.,Consultant Psychiatrist | Prasadrao G.,Consultant Psychiatrist | Dutt L.,Psychiatry Clinic | And 11 more authors.
Indian Journal of Psychiatry

Background: Alzheimer's disease (AD), a progressive brain disorder, is the most common cause of dementia among the elderly. Donepezil hydrochloride is a potent, reversible, and highly selective inhibitor of acetylcholinesterase (AChE). It is chemically distinct from other cholinesterase (ChE) inhibitors which are effective in the treatment of AD. Objectives: To evaluate the safety and efficacy of donepezil hydrochloride therapy over a 12 weeks period in patients with mild to moderate AD in Indian population. Materials and Methods: In this post-marketing study, patients with mild to moderate AD received oral donepezil hydrochloride 5 mg/day for 4 weeks followed by 10 mg/day for 8 weeks. Patients were assessed 4 times weekly for cognition on 'Mini Mental Status Examination (MMSE) scale', and function on 'Activities of Daily Living (ADL) index'. Clinicians and caregivers assessment of safety and efficacy was assessed on a 5-point rating scale. Results: One hundred and seventy two of one hundred and eighty two patients completed 12 weeks of study period. MMSE score significantly improved (P<0.0001) from 16.72 at baseline to 19.77 after 12 weeks, and there was significant improvement (P<0.05) in ADL index in 13 of 17 domains after 12 weeks. Caregivers and clinicians rated the therapy as very good to good in >80% and >90% patients, respectively. Adverse events were consistent with the known pharmacological and safety profile of donepezil. Conclusions: Donepezil is well tolerated in Indian patients with mild to moderate AD with significant improvement in cognition and function. Source

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