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Boushehr, Iran

Pakdaman E.,Islamic Azad University | Mosavi E.,Islamic Azad University | Niknam E.,Islamic Azad University | Bagheri S.,Islamic Azad University | And 2 more authors.
Der Pharma Chemica

A simple, rapid and inexpensive method for separation and pre-concentration of some traces of hazardous elements is presented prior to their flame atomic absorption spectrometric determinations. At pH 9.0±0.1; cadmium(II) and silver(I) were separated simultaneously with 2-(Phenyl)4,5-Di Phenyl Imidazole (PDPI) as a new complexing agent and floated after adding sodium dodecyl sulfate (SDS) as a foaming reagent. The floated layer was then eluted by concentrated nitric acid in methanol and introduced to the flame atomic absorption spectrometer (FAAS). These ions can be eluted quantitatively with 0.5 ml 1M HNO3 in methanol. The linear range of the determination is between 0.01-2.2 μg mL-1 for Cd2+ and, 0.02-1.9 μg mL-1 for Ag+ with a detection limits for, Cd2+ and Ag+ were 1.3 ng mL-1 and 1.4 ng mL-1, respectively. The method has been successfully applied for determination of trace amounts of ions in radiology wastewater, amalgam, natural water and blood samples. Source

Sedighi M.,Avicenna Research Institute | Aledavood S.A.,Mashhad University of Medical Sciences | Abbaszadegan M.R.,Avicenna Research Institute | Memar B.,Mashhad University of Medical Sciences | And 3 more authors.
Asian Pacific Journal of Cancer Prevention

Background: Matric metalloproteinase (MMP) 13 gene expression is increased in esophageal squamous cell carcinomas (ESCCs) and associated with increasing tumor invasion, lymph node involvement and decreased survival rates. Levels of the circulating enzyme may be elevated and used as a marker of tumor progression. In this study, clinical application of MMP-13 serum levels was evaluated for early detection, prediction of prognosis and survival time of ESCC patients. Materials and Methods: Serum levels of MMP13 were determined by ELISA in 66 ESCC patients prior of any treatment and 54 healthy controls for comparison with clinicopathological data through statistical analysis with Man Whitney U and Log-Rank tests. In addition, clinical value of MMP13 levels for diagnosis was evaluated by receiver operating characteristic (ROC) test. Results: The serum level of MMP-13 in patients (>250 pg/ml) was significantly higher than in the control group (<100 pg/ml) (p value=0.004). Also the results showed a significant correlation between MMP-13 serum levels with tumor stage (p value = 0.003), depth of tumor invasion (p value=0.008), involvement of lymph nodes (p value = 0.011), tumor size (p value = 0.018) and survival time. While there were no significant correlation with grade and location of tumors. ROC analysis showed that MMP-13 level is an accurate diagnostic marker especially to differentiate pre-invasive/invasive lesions from normal controls (sensitivity and specificity: 100%). Conclusions: These findings indicate a potential clinical significance of serum MMP13 measurement for early detection and prognostic assessment in ESCC patients. Source

Fatemi R.,Islamic Azad University | Javid M.,Islamic Azad University | Najafabadi E.M.,Payamnoor University
Journal of Back and Musculoskeletal Rehabilitation

BACKGROUND: There are many types of treatments and recommendations for restoring back deformities depending on doctors' knowledge and opinions. The purpose of the exercises is to reduce pain and to ensure stability of the lower trunk by toning the abdominal muscles, buttocks and hamstrings. Given the duration of flares and relapses rate, it is important to apply an efficient and lasting treatment. OBJECTIVE: To evaluate the effects of 8 weeks of William's training on flexibility of lumbosacral muscles and lumbar angle in females with Hyperlordosis. METHODS: Forty female students with lumbar lordosis more than normal degrees (Hyperlordotic) that were randomly divided into exercise and control groups were selected as the study sample. The lumbar lordosis was measured using a flexible ruler, flexibility of hamstring muscles was measured with the active knee extension test, the hip flexor muscles strength was measured using Thomas test, the lumbar muscles flexibility measures by Schober test, abdominal muscles strength measured by Sit-Up test and back pain was measured using McGill's Visual Analogue Scales (VAS) questionnaire. Data were compared before and post-test using independent and paired t-testes. RESULTS: Results showed that 8 weeks of William's exercise led to significant decreases in lumbar angle and back pain, increases in flexibility of hamstring muscles, hip flexor muscles flexibility, lumbar extensor muscles flexibility and abdominal muscles strength. CONCLUSION: The findings show that William's corrective training can be considered as a useful and valid method for restoring and refining back deformities like as accentuated back-arc and became wreaked muscles' performance in lumbar areas. © 2015 - IOS Press and the authors. All rights reserved. Source

Ostovan F.,Payamnoor University | Olomi H.,Kerman Graduate University of Technology | Gol A.,Shahid Bahonar University of Kerman
Physiology and Pharmacology

Introduction: Diabetes mellitus is a metabolic disorder and it is estimated that its annual incidence rate will continue to increase in the future worldwide. Increased oxidant factors and decreased antioxidant defense are two of the factors resulting in diabetes. In the present study, we aimed to investigate Citrullus Colocynthis pulp effects on oxidant and antioxidant factors of liver in streptozotocin-induced diabetic rats. Methods: Thirty-two male rats were divided into four groups eight each: N (normal) group, N+C group, D (diabetic) group, and D+C group. Groups N and D received normal saline 2ml orally for 2 weeks and Groups N+C and D+C received 10mg/kg Citrullus Colocynthis pulp orally for 2 weeks. Diabetes was induced by a single intraperitoneal injection of streptozotocin (STZ) at 65 mg/kg. Results: Diabetic group had a significant increase in H2O2 (Hydrogen peroxide), MDA (malondialdehyde) and CAT (catalase) activity and a significant decrease in POD (peroxidase) activity in liver tissues compared to N and D groups. Group D+C had a significant decrease in H2O2, MDA, and CAT concentrations in liver tissues and significant increase in POD activity in liver tissues compared to D group. Conclusion: These results suggest that treatment of diabetic rats with Citrullus colocynthis pulp decreased oxidant stress and support antioxidant defense in liver STZ-Induced diabetic rats. Source

Yari Fard R.,Wuhan University of Technology | Maleki S.E.,Islamic Azad University at Tehran | Bakhshian A.,Payamnoor University | Fard S.Y.,Islamic Azad University at Tehran
Advances in Environmental Biology

The transition from traditional society to industrial and transformation of national economies into the international economy requires a variety of tactics in order to facilitate economic growth and development in the society. Entrepreneurship and creativity are considered cornerstones of this fundamental transition. Steady economic growth which leads to international prestige and recognition could only be obtained through accurate planning and development of Entrepreneurship. Entrepreneurship is the most important source for innovation, job opportunities and development. Entrepreneurship is one of the major factors of economic growth and development besides capital and manpower, which requires creative and innovative Entrepreneurs. Encouraging Entrepreneurship attitude in the society and training motivated Entrepreneurs has a positive effect on social and economic development, for Entrepreneurs improve the overall performance of business units and enterprises through optimum utilization of resources and creation of job opportunities. This article studies the concept of Entrepreneurship in order to analyses the need for its development and application in the society in an attempt to describe its role in the social and economic growth of a nation as well as its advantages and disadvantages. © 2013 AENSI Publisher All rights reserved. Source

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