McLaughlin R.A.,University of Western Australia |
Scolaro L.,University of Western Australia |
Robbins P.,PathWest Queen Elizabeth Medical Center |
Saunders C.,Sir Charles Gairdner Hospital |
And 4 more authors.
Journal of Biomedical Optics | Year: 2010
We present a parametric optical coherence tomography (OCT) technique to improve contrast between malignant and healthy non-neoplastic tissue. The technique incorporates a fully automated method to extract tissue attenuation characteristics. Results are represented visually as a parametric en face image, where the parameter used for contrast is indicative of the relative optical attenuation coefficient of the tissue. We present the first parametric OCT images of human lymph nodes containing malignant cells, and demonstrate improved tissue contrast over en face OCT images. © 2010 Society of Photo Optical Instrumentation Engineers.