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Belem, Brazil

Rogez H.,Federal University of Para | Pompeu D.R.,Para State University | Akwie S.N.T.,Federal University of Para | Larondelle Y.,Institute Des Science Of La Vie
Journal of Food Composition and Analysis | Year: 2011

Anthocyanins are natural colorants with increasing interest. Euterpe oleracea fruits (EOF) (açai) are an interesting phenolic compounds source. They are extremely rich in two anthocyanins: cyanidin-3-glucoside and cyanidin-3-rutinoside. In this study, the anthocyanin content was evaluated in EOF during their ripening, allowing to characterize very important parameters for the post-harvest industry: their maximum accumulation rate, per day, (Δy), their maximum concentration in fruits (CMAX) and the corresponding maturity class (S). Samples of 12 racemes from three plantations were collected twice a month during their ripening process. The maturity class of EOF was recorded at each harvesting and their anthocyanin content was determined by an HPLC method after solvent extraction. Anthocyanin accumulation was described (p<0.05) by sigmoidal equations and Δy, CMAX and S values were determined. The Δy of EOF reached 35.63mgkg-1fruitsday-1, whereas CMAX reached 1443mgkg-1 fruits. On average, in the beginning of maturation, both anthocyanins were present in similar proportions. However, in the last maturity stages, cyanidin-3-glucoside became less abundant than cyanidin-3-rutinoside. On the basis of the data available on strawberries, grapes, pomegranates and lychees, it was possible to verify that the sigmoidal mathematical model of anthocyanin accumulation is transposable. © 2011 Elsevier Inc. Source


Monath T.P.,Hookipa Biotech | Monath T.P.,Paxvax, Inc. | Vasconcelos P.F.C.,Instituto Evandro Chagas | Vasconcelos P.F.C.,National Institute of Science and Technology for Viral Hemorrhagic Fevers | Vasconcelos P.F.C.,Para State University
Journal of Clinical Virology | Year: 2015

Yellow fever, a mosquito-borne flavivirus disease occurs in tropical areas of South America and Africa. It is a disease of major historical importance, but remains a threat to travelers to and residents of endemic areas despite the availability of an effective vaccine for nearly 70 years. An important aspect is the receptivity of many non-endemic areas to introduction and spread of yellow fever. This paper reviews the clinical aspects, pathogenesis, and epidemiology of yellow fever, with an emphasis on recent changes in the distribution and incidence of the disease. Recent knowledge about yellow fever 17D vaccine mechanism of action and safety are discussed. © 2014 Elsevier B.V. Source


Erythema nodosum is a rare acute reactional inflammatory dermatoses, with a prevalence of two-three cases per 10.000 in habitants per year. It can occur at any age, appearing more in women (3-5:1) between 20 and 45 years; there seems to be a seasonal incidence during the first half of the year. It is an even rarer tegumentary pathology in children. There are few isolated cases and small groups of patients reported in the medical literature. Brilliantly described by Willan in 1798 and later supplemented by von Hebra in 1866, it is a septal panniculitis with interlobular septa of the subcutaneous fatty tissue involvement without vasculitis. An immune response to different antigens with deposit of immunoglobulins (IgM) and complement fractions (C3) in the deep perivenular plexus is hipothetized, probably involving a delayed hypersensitivity reaction. It has a benign nature and autolimited course; it resolves spontaneously within three to six weeks, sometimes with outbreaks of repetition for months or even years. I present a case of a child of 9 years of age whose tegumentary lesions are associated an acute myeloblastic leukemia with fatal outcome. © 2015 Asociación Argentina de Dermatología. Source


Vasconcelos P.F.C.,Evandro Chagas Institute | Vasconcelos P.F.C.,Para State University | Calisher C.H.,Colorado State University
Vector-Borne and Zoonotic Diseases | Year: 2016

In addition to individual or clusters of cases of human infections with arboviruses, the past 15 years has seen the emergence of newly recognized arboviruses and the re-emergence of others. Mentioned in this brief summary are Bourbon, Cache Valley, chikungunya, Heartland, Itaqui, Mayaro, Oropouche, Powassan, and Zika viruses, the latter being a remarkable occurrence. © Copyright 2016, Mary Ann Liebert, Inc. 2016. Source


Santos M.I.P.O.,Para State University | Griep R.H.,Laboratorio Of Educacao Em Ambiente E Saude
Ciencia e Saude Coletiva | Year: 2013

The objective of this study was to evaluate factors associated with functional capacity among the elderly attended in a public health program in Belém in the State of Pará. A sectional study was conducted with 259 elderly people attended in the Hiperdia/SUS program in the period from March to July 2010. The elderly were assessed using the modified physical performance test duly validated in Brazil. Pearson's Chi-square Test, in addition to variance analysis and logistic regression were used for the analysis. The elderly were 68.3 years on average (SD ± 6.2) and 71% were female. After adjustments for conflicting variables, it was seen that there were greater chances of worse performance on the test among women, the older and less educated individuals, and those complaining of knee pain and prior diagnosis of cataracts and fair/bad self-assessment of health. Functional capacity is an important health indicator to identify early risks of incapacity and requiring a periodic evaluation, in order to seek care strategies for maintaining the independence of the elderly. Source

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