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Zhang Y.-H.,Pancreatic and Minimal Invasive Surgery | Hong D.-F.,Pancreatic and Minimal Invasive Surgery | Hu Z.-M.,Pancreatic and Minimal Invasive Surgery | Wu W.-D.,Pancreatic and Minimal Invasive Surgery | Zhang C.-W.,Pancreatic and Minimal Invasive Surgery
International Journal of Clinical and Experimental Medicine | Year: 2015

Factor V deficiency is a rare bleeding disorder. Fresh frozen plasma (FFP) is the only source of factor V because factor V concentrates is not available now. We present here a patient had concomitant gallbladder and common bile (CBD) stones with factor V deficiency. The patient is successfully treated by laparoscopic CBD explora­tion and cholecystectomy with perioperative fresh frozen plasma transfusion. To best of our knowledge, this is the first report of laparoscopic surgery successfully performed in a factor V deficiency patient. Our result suggest that laparoscopic surgery in a factor V deficient patient can be performed safely if normal coagulation profile is achieved after injection of FFP. Our experience in this case also indicate that the incidence of delayed bleeding after surgery is low once hemostasis is successfully obtained during operation and there is no need to continue FFP infusion beyond day 2 postoperative. © 2015 E-Century Publishing Corporation. All rights reserved. Source

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