Pezzilli R.,Pancreas Unit |
Calculli L.,SantOrsola Malpighi Hospital
Pancreas | Year: 2015
Objectives: The majority of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas are branch duct (BD) IPMNs, and these neoplasms are being diagnosed with increasing frequency; no data are also available on thewell-being (quality of life [QoL]) of these patients.We aimed to evaluate the 2-year follow-up results in consecutive patients with BD-IPMNs to assess symptoms at presentation and their morphological progression; the physical and psychological statuses of these patients were also evaluated. Methods: One hundred one patientswith BD-IPMN of the pancreaswere enrolled in the study (37.6%men and 62.4% women; mean [SD] age, 66.3 [10.4] years).Magnetic resonance imaging was used to evaluate the modification of the cystic lesions at baseline aswell as in the follow-up. The SF- 12 Health Survey, the State-Trait Anxiety Inventory Y-1 and Y-2, the 12-Item General Health Questionnaire, as well as the Beck Depression Inventory-II were used to evaluate the QoL once a year.Results: Themean (SD) basal size of themajor lesionwas 15.5 (8.9)mm, and in the follow-up period, the size remained stable. The QoL did not change during the follow-up period.Conclusions: Branch duct IPMNs are very slow-growing neoplasms, and they do not affect the QoL of affected patients. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.