Pablo De Olavide University
Seville, Spain

Pablo de Olavide University in Spanish) is a public university in Seville, Spain. UPO offers both undergraduate and graduate programs in the traditional majors, as well as in biotechnology, environmental science, humanities, labor relations, second language acquisition, social work, sports science, and translationPablo de Olavide University was founded in 1997, making it one of the newest public universities in Spain. The UPO has over 10,000 students and is growing constantly since its inception. The university is named after the Spanish-Peruvian politician Pablo de Olavide , who contributed notably to planning the city of Seville. Being a relatively young university, the UPO was planned as a North American-style campus with dedicated academic and residential space.Its 345-acres spread out southeast of Seville over the municipalities of Dos Hermanas, Alcalá de Guadaíra and Seville. Its facilities are modern, including campus-wide Wifi and Internet access, computer, television, video and audio centers, an open access library, sports facilities, and science laboratories.It has numerous sports facilities, lawns, gym and a huge library where you can find books from every subject.This University also boasts a student union building and offers easy transportation to the city center by bus or metro. Wikipedia.

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Pablo De Olavide University, Institute Salud Carlos Iii and Newbiotechnic S.A. | Date: 2017-07-19

Insulin producing cells capable of secreting blood glucose regulating hormones, specially insulin, in response to physiological signals, method of production of said cells and uses thereof.

Pablo De Olavide University, University of Seville and Servicio Andaluz De Salud | Date: 2016-03-09

The invention relates to a method for the diagnosis of liver fibrosis, comprising detecting the level of expression of the gene GATA-4, or the quantity of the protein GATA-4, in the isolated biological sample of liver tissue. The invention also relates to a diagnosis kit.

Agency: European Commission | Branch: H2020 | Program: ERC-COG | Phase: ERC-CoG-2014 | Award Amount: 2.00M | Year: 2016

European incursions onto the narrow isthmian pass that divided and connected the Atlantic and Pacific oceans made it a strategic node of the Spanish Empire and a crucial site for early modern globalization. On the front lines of the convergence of four continents, Old Panama offers an unusual opportunity for examining the diverse, often asymmetrical impacts of cultural and commercial contacts. The role of Italian, Portuguese, British, Dutch, and French interests in the area, as well as an influx of African slaves and Asian merchandise, have left a unique material legacy that requires an integrated, interdisciplinary approach to its varied sources. Bones, teeth and artifacts on this artery of Empire offer the possibility of new insights into the cultural and biological impact of early globalization. They also invite an interdisciplinary approach to different groups tactics for survival, including possible dietary changes, and the pursuit of profit. Such strategies may have led the diverse peoples inhabiting this junction, from indigenous allies to African and Asian bandits to European corsairs, to develop and to favor local production and Pacific trade networks at the expense of commerce with the metropolis. This project applies historical, archaeological and archaeometric methodologies to evidence of encounters between peoples and goods from Europe, America, Africa and Asia that took place on the Isthmus of Panama during the sixteenth and seventeenth centuries. Forging an interdisciplinary approach to early globalization, it challenges both Euro-centric and Hispano-phobic interpretations of the impact of the conquest of America, traditionally seen as a demographic catastrophe that reached its nadir in the so-called seventeenth-century crisis. Rather than applying quantitative methods to incomplete source material, researchers will adopt a contextualized, inter-disciplinary, qualitative approach to diverse agents involved in cultural and commercial exchange.

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: MSCA-NIGHT-2016 | Award Amount: 368.01K | Year: 2016

Open Researchers is the fifth experience of Andalusia in the European Researchers Night. The project is designed to increase the awareness of research as a solution to the numerous challenges faced by citizens all around the world and mainly in Europe. The idea of the project, The future is today: understandable ground-breaking science for a better living, has been conceived in a time of change, a moment where becomes clearer that we must join efforts to find sustainable, equal, innovative and creative solutions to give answer to the societal challenges. To this end, according to the RRI, it is essential to promote young peoples interest in Science and Research by opening it to general public through its main protagonists, researchers. The projects major strength is the numerous activities taking place on main streets, museums, theatres, and historical buildings of the eight Andalusian cities, the high mobilization of researchers and the involvement of Municipalities, which will have a high social impact in the region. Given the projects dimensions in a wide region with 8.3 million people, it will be developed with a high and effective presence in terms of human and technical resources, and with the collaboration of the main local institutions, NGOs, private companies, teachers and civil associations. The communication campaign aims at reach every third citizen of Andalusia, and with activities in city-centre venues around 65.000 attendees each year are expected. Fundacin Descubre will coordinate this project, based in its experience through the last 7 years working with relevant projects in Spain and fundamentally in its consortium experience in the four editions of this project in Andalusia. The consortium is composed by nine Andalusian universities, the Spanish National Research Council (CSIC), Andalusian Foundation Progress and Health, and the Royal Botanical Garden of Crdoba, all dedicated to higher education, research and Science popularization.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2013.6.3 | Award Amount: 3.35M | Year: 2014

The proposed project is an interdisciplinary effort of specialists from water management and ICT research respectively to develop an intelligent Integrated Support System for Efficient WATer USage and resources management (ISS-EWATUS). The project will develop several innovative ICT methods aiming to exploit\nthe untapped water-saving potential in EU. The overall goal will be achieved by developing an innovative, multi-factor system capable to optimise water management and reduce water usage.\n\nAt household level:\na) an information system for gathering data about water usage is planned to increase the awareness of water consumption; the data will be interpreted and presented to household consumers in an understandable way using mobile devices (smartphones, tablets),\nb) a household Decision Support System (DSS) will be developed for mobile devices to reduce water consumption. Recommendations regarding water-saving devices and behaviour will be produced,\nc) a social-media platform will be developed to reinforce water-saving behaviour of consumers via the social interactions among users (and between consumers and experts of water-saving techniques).\n\nAt urban level:\na) an innovative decision support system for reducing leaks in the water delivery system will be built based on the dynamic modifications of pumping schedules to reduce leakages at municipal level,\nb) an adaptive pricing policy will be developed as the economic instrument to induce water-saving behaviour\nand reduce peaks in water and energy distribution loads.\n\nBeing validated at two differently characterised locations, the ISS-EWATUS will be sufficiently flexible to be exploited in any EU location. Appropriate training, manuals and dissemination will give people across EU an efficient tool for water conservation. The solutions of ISS-EWATUS for households will be available on the mobile applications portals. The rest of solutions will be offered to water management companies in EU.

Fernandez-Alvarez A.,Pablo De Olavide University
PLoS pathogens | Year: 2012

The O-mannosyltransferase Pmt4 has emerged as crucial for fungal virulence in the animal pathogens Candida albicans or Cryptococcus neoformans as well as in the phytopathogenic fungus Ustilago maydis. Pmt4 O-mannosylates specific target proteins at the Endoplasmic Reticulum. Therefore a deficient O-mannosylation of these target proteins must be responsible for the loss of pathogenicity in pmt4 mutants. Taking advantage of the characteristics described for Pmt4 substrates in Saccharomyces cerevisiae, we performed a proteome-wide bioinformatic approach to identify putative Pmt4 targets in the corn smut fungus U. maydis and validated Pmt4-mediated glycosylation of candidate proteins by electrophoretic mobility shift assays. We found that the signalling mucin Msb2, which regulates appressorium differentiation upstream of the pathogenicity-related MAP kinase cascade, is O-mannosylated by Pmt4. The epistatic relationship of pmt4 and msb2 showed that both are likely to act in the same pathway. Furthermore, constitutive activation of the MAP kinase cascade restored appressorium development in pmt4 mutants, suggesting that during the initial phase of infection the failure to O-mannosylate Msb2 is responsible for the virulence defect of pmt4 mutants. On the other hand we demonstrate that during later stages of pathogenic development Pmt4 affects virulence independently of Msb2, probably by modifying secreted effector proteins. Pit1, a protein required for fungal spreading inside the infected leaf, was also identified as a Pmt4 target. Thus, O-mannosylation of different target proteins affects various stages of pathogenic development in U. maydis.

Anta J.A.,Pablo De Olavide University
Current Opinion in Colloid and Interface Science | Year: 2012

Nanostructured films of metal-oxide semiconductors are the focus of intensive research nowadays due to their applications in the current quest for new sources of clean energy. Metal-oxides like TiO 2 and ZnO can be used to make efficient photoanodes for photoelectrochemical solar cells and nanostructured substrates for photocatalytic production of non-polluting fuels. In these applications electron transport through the nanostructure is crucial to achieve a good photon-to-electron quantum efficiency. In this paper the current knowledge of the electron transport mechanisms that take place in these systems is reviewed, highlighting the influence of energy and morphological disorder on the efficacy of the transport process. A special connection is made between the specificity of the electron transport in these systems and their applications in solar cells and photocatalytic devices. © 2012 Elsevier Ltd.

Agency: European Commission | Branch: H2020 | Program: ERC-STG | Phase: ERC-StG-2015 | Award Amount: 1.50M | Year: 2016

In the last decade the approaches of the global history have been emphasized in order to visualize the progress, form and method which historians have undertaken when carrying out ambitious research projects to analyse and compare diverse geographical and cultural areas of Asia and Europe. But when dealing with comparisons and cross-cultural studies in Europe and Asia, some scholarly works have exceeded of ambiguities when defining geographical units as well as chronology. In this project I examine perceptions and dialogues between China and Europe by analysing strategic geopolitical sites which fostered commerce, consumption and socioeconomic networks between China and Europe through a particular case study: Macau, connecting with South China, and Marseille in Mediterranean Europe. How did foreign merchant networks and trans-national communities of Macau and Marseille operate during the eighteenth century and contribute to somehow transfer respectively European and Chinese socio-cultural habits and forms in local population? What was the degree and channels of consumption of European goods in China and Chinese goods in Europe? These are the main questions to answer during my research to explore the bilateral Sino-European trade relations and how the trans-national dimension of exotic commodities changed tastes by creating a new type of global consumerism. Such concrete comparison can help to narrow the gap that some researchers have created when widely analysing differences between Asia and Europe without a specific geographical and chronological delineation. The major novelty of this project is based on the use of Chinese and European sources to study changes in consumer behaviour. The principal investigator of the project works in China which is and added value for the achievement of outstanding results. So the expected results will bring an obvious breakthrough by adding the specific part of the project in which each team member will work.

Pablo De Olavide University | Date: 2016-04-27

The invention relates to the use of the inhibitor of the activity of the steroid sulfatase enzyme STX64 for treating aging, and thus for increasing the longevity of individuals or improving their quality of life. The invention also relates to a cosmetic composition comprising said inhibitor for this purpose.

Agency: European Commission | Branch: H2020 | Program: MSCA-IF-EF-ST | Phase: MSCA-IF-2014-EF | Award Amount: 170.12K | Year: 2015

This research project aims to compare the British and Spanish empires in the nineteenth-century Caribbean. More specifically, it focuses on the discourse on food in the British and Spanish colonies. This project stems from my doctoral research. My aim is both to find a connection between the ways in which food and diet were perceived and discussed in the British and Spanish Caribbean colonies and to evaluate the differences in the discourse on food in the two empires, with the objective of analyzing colonial identities and imperial ideology in the Caribbean through the lens of food. My focus on food and diet sheds light on how encounters, negotiations, appropriations, rejections and interactions of culinary practices are more than just a matter of human nutrition but rather concern fundamental issues as the construction of identities, asymmetries of power, agency of the subaltern and mutual influences. The basic assumption of this project is therefore an analysis of the relationship between food, identity and power.

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