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Sergeeva N.S.,Russian National Research Medical University | Britaev T.A.,RAS Severtsov Institute of Ecology | Sviridova I.K.,P A Hertsen Moscow Research Cancer Institute | Akhmedova S.A.,P A Hertsen Moscow Research Cancer Institute | And 5 more authors.
Bulletin of Experimental Biology and Medicine | Year: 2014

Cytocompatibility of 5 coral aquaculture skeleton species derived from two families (Acroporidae and Pocilloporidae) was studied over the course of in vitro culturing in continuous human fibroblast culture by the MMT test. Biocompatibility and capacity of scaffold to "transfer" cell cultures (specifically, multipotent mesenchymal stromal cells) to sites of implantation were studied in vivo by subcutaneous implantation of skeletal fragments to rats. All coral skeleton aquaculture specimens were cytocompatible (nontoxic and with surface matrix characteristics satisfactory for cells), biocompatible, and could be tried as 3D matrices for bone tissue engineering. © 2014 Springer Science+Business Media New York.


PubMed | P A Hertsen Moscow Research Cancer Institute
Type: Journal Article | Journal: Bulletin of experimental biology and medicine | Year: 2014

Cytocompatibility of 5 coral aquaculture skeleton species derived from two families (Acroporidae and Pocilloporidae) was studied over the course of in vitro culturing in continuous human fibroblast culture by the MMT test. Biocompatibility and capacity of scaffold to transfer cell cultures (specifically, multipotent mesenchymal stromal cells) to sites of implantation were studied in vivo by subcutaneous implantation of skeletal fragments to rats. All coral skeleton aquaculture specimens were cytocompatible (nontoxic and with surface matrix characteristics satisfactory for cells), biocompatible, and could be tried as 3D matrices for bone tissue engineering.

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